Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]
Autor(a) principal: | |
---|---|
Data de Publicação: | 2007 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Scientia Medica (Porto Alegre. Online) |
Texto Completo: | https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588 |
Resumo: | Aims: To evaluate the prevalence of antibodies against hepatitis C virus in patients undergoing hemodialysis and to investigate the present condition of 71 patients who participated in a study conducted at the same hemodialysis unit from 2000 to 2002. Methods: Patients seropositive for hepatitis C virus (anti-HCV reactive) were identified among those undergoing hemodialysis at Hospital São Lucas da PUCRS in May 2006. Seventy-one patients who underwent hemodialysis from a previous study (2000-2002) of prevalence of HCV were also studied. These subjects were followed through medical records. The results were described and compared with the literature. Results: I May 2006, among the 70 patients undergoing hemodialysis at DU-SLH, 7 (10%) were anti-HCV reactive. Regarding the 71 patients from the 2000-2002 study, 24 (33.8%) still attend São Lucas Hospital, 12 (16.9%) undergoing hemodialysis and 12 (16.9%) after renal transplantation. Twenty two patients (31%) have dyed, the majority of them due to cardiovascular causes. Twenty five (35.2%) patients are no more in contact with the Institution. Conclusions: Anti-HCV prevalence detected among patients undergoing hemodialysis in May 2006 was significantly different from that observed in the 2000-2002 study. Apparently, hepatitis C infection had no influence on the mortality or prognosis of anti-HCV positive patients from the 2000-2002 study, once the major registered cause of death was cardiovascular problems. KEY WORDS: HEPATITIS C; PREVALENCE; HEPATITIS C ANTIBODIES; HEMODIALYSIS UNITS, HOSPITAL; HEMODIALYSIS. |
id |
PUC_RS-25_39d748d38251ce023eacf8f95e819b7f |
---|---|
oai_identifier_str |
oai:ojs.revistaseletronicas.pucrs.br:article/1588 |
network_acronym_str |
PUC_RS-25 |
network_name_str |
Scientia Medica (Porto Alegre. Online) |
repository_id_str |
|
spelling |
Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]Comportamento da hepatite viral C nos pacientes em programa de hemodiálise do Hospital São Lucas da PUCRSHepatite viral CAims: To evaluate the prevalence of antibodies against hepatitis C virus in patients undergoing hemodialysis and to investigate the present condition of 71 patients who participated in a study conducted at the same hemodialysis unit from 2000 to 2002. Methods: Patients seropositive for hepatitis C virus (anti-HCV reactive) were identified among those undergoing hemodialysis at Hospital São Lucas da PUCRS in May 2006. Seventy-one patients who underwent hemodialysis from a previous study (2000-2002) of prevalence of HCV were also studied. These subjects were followed through medical records. The results were described and compared with the literature. Results: I May 2006, among the 70 patients undergoing hemodialysis at DU-SLH, 7 (10%) were anti-HCV reactive. Regarding the 71 patients from the 2000-2002 study, 24 (33.8%) still attend São Lucas Hospital, 12 (16.9%) undergoing hemodialysis and 12 (16.9%) after renal transplantation. Twenty two patients (31%) have dyed, the majority of them due to cardiovascular causes. Twenty five (35.2%) patients are no more in contact with the Institution. Conclusions: Anti-HCV prevalence detected among patients undergoing hemodialysis in May 2006 was significantly different from that observed in the 2000-2002 study. Apparently, hepatitis C infection had no influence on the mortality or prognosis of anti-HCV positive patients from the 2000-2002 study, once the major registered cause of death was cardiovascular problems. KEY WORDS: HEPATITIS C; PREVALENCE; HEPATITIS C ANTIBODIES; HEMODIALYSIS UNITS, HOSPITAL; HEMODIALYSIS.Objetivos: Avaliar a prevalência de anticorpos positivos para hepatite C nos pacientes em programa de hemodiálise e realizar o seguimento desta amostra de pacientes em programa de hemodiálise, quanto à permanência em hemodiálise, realização de transplante renal, mortalidade e influência do vírus da hepatite C sobre mortalidade entre aqueles com PCR para HCV-RNA positivo. Métodos: Foram identificados os pacientes em programa de hemodiálise no Hospital São Lucas da PUCRS em maio de 2006, analisando a sorologia positiva para hepatite C, através de anti-HCV reagente. Também foram estudados, retrospectivamente, 71 pacientes que estavam em hemodiálise no período de 2000 a 2002 e que participaram de estudo prévio a respeito de prevalência de anti-HCV positivo e/ou HCV-RNA positivo. Foi realizado o seguimento destes pacientes através de revisão de prontuário médico. Os resultados foram apresentados de forma descritiva e comparados com a literatura. Resultados: Setenta pacientes estavam em programa de hemodiálise no mês de maio de 2006, entre os quais 7 (10%) tinham anticorpos positivos para hepatite C. Dos 71 pacientes que participaram do estudo entre 2000 e 2002, 24 (33,8%) permaneciam em acompanhamento no HSL-PUCRS, sendo que 12 (16,9%) em programa de hemodiálise e 12 (16,9%) realizaram transplante renal. Vinte e dois pacientes (31%) foram a óbito, sendo que as causas mais freqüentes foram as cardiovasculares (36,3%). Vinte e cinco pacientes (35,2%) perderam o vínculo com a instituição. Entre os 71 pacientes, 15 apresentavam anticorpos para o vírus C e 7 tinham a sorologia (anti-HCV) negativa. Entretanto, a detecção do HCV–RNA era positiva. Os restantes tinham tanto anti-HCV quanto HCV-RNA negativos. Conclusões: A prevalência atual de anticorpos positivos para hepatite C nos pacientes em hemodiálise não se alterou significativamente em relação ao período de 2002. Não foi possível identificar influência da infecção pelo vírus da hepatite C na mortalidade e no prognóstico dos pacientes em programa de hemodiálise. A causa de óbito mais freqüentemente encontrada foi a cardiovascular. DESCRITORES: HEPATITE C; PREVALÊNCIA; ANTICORPOS ANTI-HEPATITE C; UNIDADES HOSPITALARES DE HEMODIÁLISE; HEMODIÁLISE.Editora da PUCRS - ediPUCRS2007-10-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionEstudo de prevalênciaapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588Scientia Medica; Vol. 16 No. 3 (2006); 115-118Scientia Medica; v. 16 n. 3 (2006); 115-1181980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588/1789https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588/7991Callegaro, Fabiane P.Kupski, CarlosNascimento, Roberto C. doSchmitt, Virgínia M.info:eu-repo/semantics/openAccess2013-07-17T17:32:05Zoai:ojs.revistaseletronicas.pucrs.br:article/1588Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2013-07-17T17:32:05Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.none.fl_str_mv |
Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English] Comportamento da hepatite viral C nos pacientes em programa de hemodiálise do Hospital São Lucas da PUCRS |
title |
Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English] |
spellingShingle |
Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English] Callegaro, Fabiane P. Hepatite viral C |
title_short |
Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English] |
title_full |
Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English] |
title_fullStr |
Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English] |
title_full_unstemmed |
Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English] |
title_sort |
Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English] |
author |
Callegaro, Fabiane P. |
author_facet |
Callegaro, Fabiane P. Kupski, Carlos Nascimento, Roberto C. do Schmitt, Virgínia M. |
author_role |
author |
author2 |
Kupski, Carlos Nascimento, Roberto C. do Schmitt, Virgínia M. |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Callegaro, Fabiane P. Kupski, Carlos Nascimento, Roberto C. do Schmitt, Virgínia M. |
dc.subject.por.fl_str_mv |
Hepatite viral C |
topic |
Hepatite viral C |
description |
Aims: To evaluate the prevalence of antibodies against hepatitis C virus in patients undergoing hemodialysis and to investigate the present condition of 71 patients who participated in a study conducted at the same hemodialysis unit from 2000 to 2002. Methods: Patients seropositive for hepatitis C virus (anti-HCV reactive) were identified among those undergoing hemodialysis at Hospital São Lucas da PUCRS in May 2006. Seventy-one patients who underwent hemodialysis from a previous study (2000-2002) of prevalence of HCV were also studied. These subjects were followed through medical records. The results were described and compared with the literature. Results: I May 2006, among the 70 patients undergoing hemodialysis at DU-SLH, 7 (10%) were anti-HCV reactive. Regarding the 71 patients from the 2000-2002 study, 24 (33.8%) still attend São Lucas Hospital, 12 (16.9%) undergoing hemodialysis and 12 (16.9%) after renal transplantation. Twenty two patients (31%) have dyed, the majority of them due to cardiovascular causes. Twenty five (35.2%) patients are no more in contact with the Institution. Conclusions: Anti-HCV prevalence detected among patients undergoing hemodialysis in May 2006 was significantly different from that observed in the 2000-2002 study. Apparently, hepatitis C infection had no influence on the mortality or prognosis of anti-HCV positive patients from the 2000-2002 study, once the major registered cause of death was cardiovascular problems. KEY WORDS: HEPATITIS C; PREVALENCE; HEPATITIS C ANTIBODIES; HEMODIALYSIS UNITS, HOSPITAL; HEMODIALYSIS. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-10-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Estudo de prevalência |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588 |
url |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588/1789 https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588/7991 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
dc.source.none.fl_str_mv |
Scientia Medica; Vol. 16 No. 3 (2006); 115-118 Scientia Medica; v. 16 n. 3 (2006); 115-118 1980-6108 1806-5562 reponame:Scientia Medica (Porto Alegre. Online) instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Scientia Medica (Porto Alegre. Online) |
collection |
Scientia Medica (Porto Alegre. Online) |
repository.name.fl_str_mv |
Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
scientiamedica@pucrs.br || editora.periodicos@pucrs.br |
_version_ |
1809101748418117632 |