Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]

Detalhes bibliográficos
Autor(a) principal: Callegaro, Fabiane P.
Data de Publicação: 2007
Outros Autores: Kupski, Carlos, Nascimento, Roberto C. do, Schmitt, Virgínia M.
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Scientia Medica (Porto Alegre. Online)
Texto Completo: https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588
Resumo: Aims: To evaluate the prevalence of antibodies against hepatitis C virus in patients undergoing hemodialysis and to investigate the present condition of 71 patients who participated in a study conducted at the same hemodialysis unit from 2000 to 2002. Methods: Patients seropositive for hepatitis C virus (anti-HCV reactive) were identified among those undergoing hemodialysis at Hospital São Lucas da PUCRS in May 2006. Seventy-one patients who underwent hemodialysis from a previous study (2000-2002) of prevalence of HCV were also studied. These subjects were followed through medical records. The results were described and compared with the literature. Results: I May 2006, among the 70 patients undergoing hemodialysis at DU-SLH, 7 (10%) were anti-HCV reactive. Regarding the 71 patients from the 2000-2002 study, 24 (33.8%) still attend São Lucas Hospital, 12 (16.9%) undergoing hemodialysis and 12 (16.9%) after renal transplantation. Twenty two patients (31%) have dyed, the majority of them due to cardiovascular causes. Twenty five (35.2%) patients are no more in contact with the Institution. Conclusions: Anti-HCV prevalence detected among patients undergoing hemodialysis in May 2006 was significantly different from that observed in the 2000-2002 study. Apparently, hepatitis C infection had no influence on the mortality or prognosis of anti-HCV positive patients from the 2000-2002 study, once the major registered cause of death was cardiovascular problems. KEY WORDS: HEPATITIS C; PREVALENCE; HEPATITIS C ANTIBODIES; HEMODIALYSIS UNITS, HOSPITAL; HEMODIALYSIS.
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spelling Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]Comportamento da hepatite viral C nos pacientes em programa de hemodiálise do Hospital São Lucas da PUCRSHepatite viral CAims: To evaluate the prevalence of antibodies against hepatitis C virus in patients undergoing hemodialysis and to investigate the present condition of 71 patients who participated in a study conducted at the same hemodialysis unit from 2000 to 2002. Methods: Patients seropositive for hepatitis C virus (anti-HCV reactive) were identified among those undergoing hemodialysis at Hospital São Lucas da PUCRS in May 2006. Seventy-one patients who underwent hemodialysis from a previous study (2000-2002) of prevalence of HCV were also studied. These subjects were followed through medical records. The results were described and compared with the literature. Results: I May 2006, among the 70 patients undergoing hemodialysis at DU-SLH, 7 (10%) were anti-HCV reactive. Regarding the 71 patients from the 2000-2002 study, 24 (33.8%) still attend São Lucas Hospital, 12 (16.9%) undergoing hemodialysis and 12 (16.9%) after renal transplantation. Twenty two patients (31%) have dyed, the majority of them due to cardiovascular causes. Twenty five (35.2%) patients are no more in contact with the Institution. Conclusions: Anti-HCV prevalence detected among patients undergoing hemodialysis in May 2006 was significantly different from that observed in the 2000-2002 study. Apparently, hepatitis C infection had no influence on the mortality or prognosis of anti-HCV positive patients from the 2000-2002 study, once the major registered cause of death was cardiovascular problems. KEY WORDS: HEPATITIS C; PREVALENCE; HEPATITIS C ANTIBODIES; HEMODIALYSIS UNITS, HOSPITAL; HEMODIALYSIS.Objetivos: Avaliar a prevalência de anticorpos positivos para hepatite C nos pacientes em programa de hemodiálise e realizar o seguimento desta amostra de pacientes em programa de hemodiálise, quanto à permanência em hemodiálise, realização de transplante renal, mortalidade e influência do vírus da hepatite C sobre mortalidade entre aqueles com PCR para HCV-RNA positivo. Métodos: Foram identificados os pacientes em programa de hemodiálise no Hospital São Lucas da PUCRS em maio de 2006, analisando a sorologia positiva para hepatite C, através de anti-HCV reagente. Também foram estudados, retrospectivamente, 71 pacientes que estavam em hemodiálise no período de 2000 a 2002 e que participaram de estudo prévio a respeito de prevalência de anti-HCV positivo e/ou HCV-RNA positivo. Foi realizado o seguimento destes pacientes através de revisão de prontuário médico. Os resultados foram apresentados de forma descritiva e comparados com a literatura. Resultados: Setenta pacientes estavam em programa de hemodiálise no mês de maio de 2006, entre os quais 7 (10%) tinham anticorpos positivos para hepatite C. Dos 71 pacientes que participaram do estudo entre 2000 e 2002, 24 (33,8%) permaneciam em acompanhamento no HSL-PUCRS, sendo que 12 (16,9%) em programa de hemodiálise e 12 (16,9%) realizaram transplante renal. Vinte e dois pacientes (31%) foram a óbito, sendo que as causas mais freqüentes foram as cardiovasculares (36,3%). Vinte e cinco pacientes (35,2%) perderam o vínculo com a instituição. Entre os 71 pacientes, 15 apresentavam anticorpos para o vírus C e 7 tinham a sorologia (anti-HCV) negativa. Entretanto, a detecção do HCV–RNA era positiva. Os restantes tinham tanto anti-HCV quanto HCV-RNA negativos. Conclusões: A prevalência atual de anticorpos positivos para hepatite C nos pacientes em hemodiálise não se alterou significativamente em relação ao período de 2002. Não foi possível identificar influência da infecção pelo vírus da hepatite C na mortalidade e no prognóstico dos pacientes em programa de hemodiálise. A causa de óbito mais freqüentemente encontrada foi a cardiovascular. DESCRITORES: HEPATITE C; PREVALÊNCIA; ANTICORPOS ANTI-HEPATITE C; UNIDADES HOSPITALARES DE HEMODIÁLISE; HEMODIÁLISE.Editora da PUCRS - ediPUCRS2007-10-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionEstudo de prevalênciaapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588Scientia Medica; Vol. 16 No. 3 (2006); 115-118Scientia Medica; v. 16 n. 3 (2006); 115-1181980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588/1789https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588/7991Callegaro, Fabiane P.Kupski, CarlosNascimento, Roberto C. doSchmitt, Virgínia M.info:eu-repo/semantics/openAccess2013-07-17T17:32:05Zoai:ojs.revistaseletronicas.pucrs.br:article/1588Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2013-07-17T17:32:05Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]
Comportamento da hepatite viral C nos pacientes em programa de hemodiálise do Hospital São Lucas da PUCRS
title Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]
spellingShingle Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]
Callegaro, Fabiane P.
Hepatite viral C
title_short Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]
title_full Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]
title_fullStr Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]
title_full_unstemmed Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]
title_sort Behavior of viral hepatitis C in patients from hemodialysis program from Hospital São Lucas da PUCRS [Abstract in English]
author Callegaro, Fabiane P.
author_facet Callegaro, Fabiane P.
Kupski, Carlos
Nascimento, Roberto C. do
Schmitt, Virgínia M.
author_role author
author2 Kupski, Carlos
Nascimento, Roberto C. do
Schmitt, Virgínia M.
author2_role author
author
author
dc.contributor.author.fl_str_mv Callegaro, Fabiane P.
Kupski, Carlos
Nascimento, Roberto C. do
Schmitt, Virgínia M.
dc.subject.por.fl_str_mv Hepatite viral C
topic Hepatite viral C
description Aims: To evaluate the prevalence of antibodies against hepatitis C virus in patients undergoing hemodialysis and to investigate the present condition of 71 patients who participated in a study conducted at the same hemodialysis unit from 2000 to 2002. Methods: Patients seropositive for hepatitis C virus (anti-HCV reactive) were identified among those undergoing hemodialysis at Hospital São Lucas da PUCRS in May 2006. Seventy-one patients who underwent hemodialysis from a previous study (2000-2002) of prevalence of HCV were also studied. These subjects were followed through medical records. The results were described and compared with the literature. Results: I May 2006, among the 70 patients undergoing hemodialysis at DU-SLH, 7 (10%) were anti-HCV reactive. Regarding the 71 patients from the 2000-2002 study, 24 (33.8%) still attend São Lucas Hospital, 12 (16.9%) undergoing hemodialysis and 12 (16.9%) after renal transplantation. Twenty two patients (31%) have dyed, the majority of them due to cardiovascular causes. Twenty five (35.2%) patients are no more in contact with the Institution. Conclusions: Anti-HCV prevalence detected among patients undergoing hemodialysis in May 2006 was significantly different from that observed in the 2000-2002 study. Apparently, hepatitis C infection had no influence on the mortality or prognosis of anti-HCV positive patients from the 2000-2002 study, once the major registered cause of death was cardiovascular problems. KEY WORDS: HEPATITIS C; PREVALENCE; HEPATITIS C ANTIBODIES; HEMODIALYSIS UNITS, HOSPITAL; HEMODIALYSIS.
publishDate 2007
dc.date.none.fl_str_mv 2007-10-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Estudo de prevalência
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dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588
url https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588/1789
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1588/7991
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
dc.source.none.fl_str_mv Scientia Medica; Vol. 16 No. 3 (2006); 115-118
Scientia Medica; v. 16 n. 3 (2006); 115-118
1980-6108
1806-5562
reponame:Scientia Medica (Porto Alegre. Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Scientia Medica (Porto Alegre. Online)
collection Scientia Medica (Porto Alegre. Online)
repository.name.fl_str_mv Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv scientiamedica@pucrs.br || editora.periodicos@pucrs.br
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