Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, Brazil

Detalhes bibliográficos
Autor(a) principal: Santos, Silvana Oliveira dos
Data de Publicação: 2014
Outros Autores: Brezolin, Daiane, Hörner, Rosmari
Tipo de documento: Artigo
Idioma: por
Título da fonte: Scientia Medica (Porto Alegre. Online)
Texto Completo: https://revistaseletronicas.pucrs.br/scientiamedica/article/view/15809
Resumo: AIMS: To evaluate the characteristics of antimicrobial susceptibility of carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa isolated from August 2011 to January 2012 from inpatients at the University Hospital of Santa Maria, Santa Maria, Rio Grande do Sul, Brazil. METHODS: A retrospective study was conducted by consulting the database of the Microbiology Laboratory, which included all isolates of Acinetobacter spp. and P. aeruginosa from different clinical specimens collected from hospitalized patients who had resistant or intermediate profile to carbapenemic antimicrobials used in this hospital (imipenem, meropenem and ertapenem) verified through conventional methodology by disc diffusion (Kirby-Bauer) or automated method (MicroScan ® - Siemens) according to the standards recommended by the Clinical and Laboratory Standards Institute. RESULTS: In the studied period 58 samples of nonfermenters Gram-negative bacilli resistant to carbapenems were found, 32 of the genus Acinetobacter and 26 of P. aeruginosa. Acinetobacter spp. was more isolated in the intensive care unit, while P. aeruginosa prevailed in the emergency and outpatient departments. Both microorganisms came mainly from respiratory secretions. CONCLUSIONS: In this study, Acinetobacter spp. and P. aeruginosa showed high antimicrobial resistance. Polymyxin B was a good antimicrobial for the treatment of infections caused by microorganisms resistant to carbapenems in this hospital.
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spelling Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, BrazilAcinetobacter spp. e Pseudomonas aeruginosa resistentes aos carbapenêmicos no Hospital Universitário de Santa MariaACINETOBACTER SPP.PSEUDOMONAS AERUGINOSACARBAPENEMSANTIBIOTIC RESISTANCEBACTERIALMULTIDRUG RESISTANCENOSOCOMIAL INFECTIONSGRAM-NEGATIVE BACTERIAL INFECTIONSAIMS: To evaluate the characteristics of antimicrobial susceptibility of carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa isolated from August 2011 to January 2012 from inpatients at the University Hospital of Santa Maria, Santa Maria, Rio Grande do Sul, Brazil. METHODS: A retrospective study was conducted by consulting the database of the Microbiology Laboratory, which included all isolates of Acinetobacter spp. and P. aeruginosa from different clinical specimens collected from hospitalized patients who had resistant or intermediate profile to carbapenemic antimicrobials used in this hospital (imipenem, meropenem and ertapenem) verified through conventional methodology by disc diffusion (Kirby-Bauer) or automated method (MicroScan ® - Siemens) according to the standards recommended by the Clinical and Laboratory Standards Institute. RESULTS: In the studied period 58 samples of nonfermenters Gram-negative bacilli resistant to carbapenems were found, 32 of the genus Acinetobacter and 26 of P. aeruginosa. Acinetobacter spp. was more isolated in the intensive care unit, while P. aeruginosa prevailed in the emergency and outpatient departments. Both microorganisms came mainly from respiratory secretions. CONCLUSIONS: In this study, Acinetobacter spp. and P. aeruginosa showed high antimicrobial resistance. Polymyxin B was a good antimicrobial for the treatment of infections caused by microorganisms resistant to carbapenems in this hospital.OBJETIVOS: Avaliar Acinetobacter spp. e P. aeruginosa resistentes aos carbapenêmicos, isolados entre agosto de 2011 a janeiro de 2012 de pacientes internados no Hospital Universitário de Santa Maria, Santa Maria, Rio Grande do Sul, Brasil. MÉTODOS: Os testes de sensibilidade aos antimicrobianos foram realizados pelo método de difusão do disco e/ou através da metodologia automatizada (MicroScan® – Siemens), seguindo recomendações do Clinical and Laboratory Standards Institut (CLSI). RESULTADOS: Neste estudo, todos os isolados de Acinetobacter spp. e P. aeruginosa foram sensíveis à polimixina B. CONCLUSÕES: Neste nosocômio, sugere-se polimixina B como terapia empírica para bacilos gram negativos não fermentadores de glicose resistentes aos carbapenêmicos.Editora da PUCRS - ediPUCRS2014-05-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionretrospectivapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1580910.15448/1980-6108.2014.2.15809Scientia Medica; Vol. 24 No. 2 (2014); 150-155Scientia Medica; v. 24 n. 2 (2014); 150-1551980-61081806-556210.15448/1980-6108.2014.2reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/15809/11484Santos, Silvana Oliveira dosBrezolin, DaianeHörner, Rosmariinfo:eu-repo/semantics/openAccess2017-08-28T14:51:15Zoai:ojs.revistaseletronicas.pucrs.br:article/15809Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2017-08-28T14:51:15Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, Brazil
Acinetobacter spp. e Pseudomonas aeruginosa resistentes aos carbapenêmicos no Hospital Universitário de Santa Maria
title Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, Brazil
spellingShingle Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, Brazil
Santos, Silvana Oliveira dos
ACINETOBACTER SPP.
PSEUDOMONAS AERUGINOSA
CARBAPENEMS
ANTIBIOTIC RESISTANCE
BACTERIAL
MULTIDRUG RESISTANCE
NOSOCOMIAL INFECTIONS
GRAM-NEGATIVE BACTERIAL INFECTIONS
title_short Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, Brazil
title_full Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, Brazil
title_fullStr Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, Brazil
title_full_unstemmed Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, Brazil
title_sort Carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa at the University Hospital of Santa Maria, Rio Grande do Sul state, Brazil
author Santos, Silvana Oliveira dos
author_facet Santos, Silvana Oliveira dos
Brezolin, Daiane
Hörner, Rosmari
author_role author
author2 Brezolin, Daiane
Hörner, Rosmari
author2_role author
author
dc.contributor.author.fl_str_mv Santos, Silvana Oliveira dos
Brezolin, Daiane
Hörner, Rosmari
dc.subject.por.fl_str_mv ACINETOBACTER SPP.
PSEUDOMONAS AERUGINOSA
CARBAPENEMS
ANTIBIOTIC RESISTANCE
BACTERIAL
MULTIDRUG RESISTANCE
NOSOCOMIAL INFECTIONS
GRAM-NEGATIVE BACTERIAL INFECTIONS
topic ACINETOBACTER SPP.
PSEUDOMONAS AERUGINOSA
CARBAPENEMS
ANTIBIOTIC RESISTANCE
BACTERIAL
MULTIDRUG RESISTANCE
NOSOCOMIAL INFECTIONS
GRAM-NEGATIVE BACTERIAL INFECTIONS
description AIMS: To evaluate the characteristics of antimicrobial susceptibility of carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa isolated from August 2011 to January 2012 from inpatients at the University Hospital of Santa Maria, Santa Maria, Rio Grande do Sul, Brazil. METHODS: A retrospective study was conducted by consulting the database of the Microbiology Laboratory, which included all isolates of Acinetobacter spp. and P. aeruginosa from different clinical specimens collected from hospitalized patients who had resistant or intermediate profile to carbapenemic antimicrobials used in this hospital (imipenem, meropenem and ertapenem) verified through conventional methodology by disc diffusion (Kirby-Bauer) or automated method (MicroScan ® - Siemens) according to the standards recommended by the Clinical and Laboratory Standards Institute. RESULTS: In the studied period 58 samples of nonfermenters Gram-negative bacilli resistant to carbapenems were found, 32 of the genus Acinetobacter and 26 of P. aeruginosa. Acinetobacter spp. was more isolated in the intensive care unit, while P. aeruginosa prevailed in the emergency and outpatient departments. Both microorganisms came mainly from respiratory secretions. CONCLUSIONS: In this study, Acinetobacter spp. and P. aeruginosa showed high antimicrobial resistance. Polymyxin B was a good antimicrobial for the treatment of infections caused by microorganisms resistant to carbapenems in this hospital.
publishDate 2014
dc.date.none.fl_str_mv 2014-05-17
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
retrospectiv
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/15809
10.15448/1980-6108.2014.2.15809
url https://revistaseletronicas.pucrs.br/scientiamedica/article/view/15809
identifier_str_mv 10.15448/1980-6108.2014.2.15809
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/15809/11484
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
dc.source.none.fl_str_mv Scientia Medica; Vol. 24 No. 2 (2014); 150-155
Scientia Medica; v. 24 n. 2 (2014); 150-155
1980-6108
1806-5562
10.15448/1980-6108.2014.2
reponame:Scientia Medica (Porto Alegre. Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Scientia Medica (Porto Alegre. Online)
collection Scientia Medica (Porto Alegre. Online)
repository.name.fl_str_mv Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv scientiamedica@pucrs.br || editora.periodicos@pucrs.br
_version_ 1809101750159802368

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