Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English]
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Scientia Medica (Porto Alegre. Online) |
Texto Completo: | https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1636 |
Resumo: | Aims: To evaluate the utilization of Toxoplasma gondii (T. gondii) IgG avidity test in the laboratory routine of prenatal care in pregnant women from Araraquara/SP and to analyse its relationship with the antiparasitic treatment and the occurrence of congenital toxoplasmosis. Methods: From January to November 2005, at the Laboratório de Imunologia Clínica e Biologia Molecular do Centro de Referência Diagnóstica do Núcleo de Atendimento à Comunidade da Universidade Auxiliar Integrada à Faculdade de Ciências Farmacêuticas, Campus de Araraquara, UNESP, Araraquara/SP, the results of the serological tests for toxoplasmosis in the prenatal care routine were analyzed in two groups of patients. One consisting of pregnant women with negative T. gondiispecific IgM (n=200) and the other consisting of pregnant women with positive T. gondii-specific IgM (n=33). The T. gondii-specific IgG avidity test was performed in the group with positive T. gondii-specific IgM. Results: Most pregnant women (76.9%) who presented intermediate avidity test results received antiparasitic treatment. Of the 16 pregnant women who presented high avidity results, nine (56,25%) received antiparasitic treatment. Conclusions: Even in the presence of a high specific- T. gondii IgG avidity test in the first trimester of gestation, the antiparasitic treatment was instituted, demonstrating that the avidity test was not adequately utilized in the clinical practice. KEY WORDS: TOXOPLASMOSIS, CONGENITAL/PREVENTION & CONTROL; TOXOPLASMA/IMMUNOLOGY; ANTIBODY AFFINITY; SEROLOGIC TESTS; IMUNOGLOBULIN G/ANALYSIS; PRENATAL CARE; CROSS-SECTIONAL STUDIES. |
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Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English]Toxoplasmose em gestantes de Araraquara/SP: análise da utilização do teste de avidez de IgG anti-Toxoplasma na rotina do pré-natalToxoplasmose em gestantesAims: To evaluate the utilization of Toxoplasma gondii (T. gondii) IgG avidity test in the laboratory routine of prenatal care in pregnant women from Araraquara/SP and to analyse its relationship with the antiparasitic treatment and the occurrence of congenital toxoplasmosis. Methods: From January to November 2005, at the Laboratório de Imunologia Clínica e Biologia Molecular do Centro de Referência Diagnóstica do Núcleo de Atendimento à Comunidade da Universidade Auxiliar Integrada à Faculdade de Ciências Farmacêuticas, Campus de Araraquara, UNESP, Araraquara/SP, the results of the serological tests for toxoplasmosis in the prenatal care routine were analyzed in two groups of patients. One consisting of pregnant women with negative T. gondiispecific IgM (n=200) and the other consisting of pregnant women with positive T. gondii-specific IgM (n=33). The T. gondii-specific IgG avidity test was performed in the group with positive T. gondii-specific IgM. Results: Most pregnant women (76.9%) who presented intermediate avidity test results received antiparasitic treatment. Of the 16 pregnant women who presented high avidity results, nine (56,25%) received antiparasitic treatment. Conclusions: Even in the presence of a high specific- T. gondii IgG avidity test in the first trimester of gestation, the antiparasitic treatment was instituted, demonstrating that the avidity test was not adequately utilized in the clinical practice. KEY WORDS: TOXOPLASMOSIS, CONGENITAL/PREVENTION & CONTROL; TOXOPLASMA/IMMUNOLOGY; ANTIBODY AFFINITY; SEROLOGIC TESTS; IMUNOGLOBULIN G/ANALYSIS; PRENATAL CARE; CROSS-SECTIONAL STUDIES.Objetivos: Avaliar a utilização do teste de avidez de IgG anti-Toxoplasma gondii (T. gondii) na rotina laboratorial do pré-natal, entre gestantes do município de Araraquara/SP e região, e analisar sua relação com a realização de tratamento para toxoplasmose durante a gestação e com a ocorrência de toxoplasmose congênita. Métodos: De janeiro a novembro de 2005, no Laboratório de Imunologia Clínica e Biologia Molecular do Centro de Referência Diagnóstica do Núcleo de Atendimento à Comunidade da Universidade Auxiliar Integrada à Faculdade de Ciências Farmacêuticas, Campus de Araraquara, UNESP, Araraquara/SP, analisaram-se os resultados dos testes sorológicos para toxoplasmose na rotina do pré-natal em dois grupos de pacientes. O primeiro constituído por gestantes com IgM anti-T. gondii negativa (n=200) e o outro constituído por gestantes com IgM anti-T. gondii positiva (n=33). No grupo com IgM positiva foi realizado o teste de avidez para anticorpos IgG anti-T. gondii. Resultados: A maioria das gestantes (76,9%) que apresentaram taxas de avidez intermediárias realizou tratamento antiparasitário. Entre as 16 gestantes que apresentaram taxas de avidez de IgG alta, nove (56,25%) realizaram tratamento antiparasitário. Conclusões: O tratamento antiparasitário foi prescrito para algumas gestantes mesmo na presença de uma taxa de avidez de IgG anti-T. gondii alta no primeiro trimestre da gestação, mostrando que o teste de avidez não foi corretamente interpretado e utilizado na prática clínica. DESCRITORES: TOXOPLASMOSE CONGÊNITA/PREVENÇÃO & CONTROLE; TOXOPLASMA/IMUNOLOGIA; AFINIDADE DE ANTICORPOS; TESTES SOROLÓGICOS; IMUNOGLOBULINA G/ANÁLISE; CUIDADO PRÉ-NATAL; ESTUDOS TRANSVERSAIS.Editora da PUCRS - ediPUCRS2007-09-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionEstudo diagnósticoapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1636Scientia Medica; Vol. 17 No. 2 (2007); 57-62Scientia Medica; v. 17 n. 2 (2007); 57-621980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1636/1899https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1636/7879Isabel, Thais Ferreirada Costa, Paulo InácioSimões, Maria Jacira Silvainfo:eu-repo/semantics/openAccess2013-07-17T13:30:50Zoai:ojs.revistaseletronicas.pucrs.br:article/1636Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2013-07-17T13:30:50Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.none.fl_str_mv |
Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English] Toxoplasmose em gestantes de Araraquara/SP: análise da utilização do teste de avidez de IgG anti-Toxoplasma na rotina do pré-natal |
title |
Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English] |
spellingShingle |
Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English] Isabel, Thais Ferreira Toxoplasmose em gestantes |
title_short |
Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English] |
title_full |
Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English] |
title_fullStr |
Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English] |
title_full_unstemmed |
Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English] |
title_sort |
Toxoplasmosis in pregnant women from Araraquara/SP: Analysis of Toxoplasma-specific IgG avidity test utilization in the prenatal care routine [Abstract in English] |
author |
Isabel, Thais Ferreira |
author_facet |
Isabel, Thais Ferreira da Costa, Paulo Inácio Simões, Maria Jacira Silva |
author_role |
author |
author2 |
da Costa, Paulo Inácio Simões, Maria Jacira Silva |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Isabel, Thais Ferreira da Costa, Paulo Inácio Simões, Maria Jacira Silva |
dc.subject.por.fl_str_mv |
Toxoplasmose em gestantes |
topic |
Toxoplasmose em gestantes |
description |
Aims: To evaluate the utilization of Toxoplasma gondii (T. gondii) IgG avidity test in the laboratory routine of prenatal care in pregnant women from Araraquara/SP and to analyse its relationship with the antiparasitic treatment and the occurrence of congenital toxoplasmosis. Methods: From January to November 2005, at the Laboratório de Imunologia Clínica e Biologia Molecular do Centro de Referência Diagnóstica do Núcleo de Atendimento à Comunidade da Universidade Auxiliar Integrada à Faculdade de Ciências Farmacêuticas, Campus de Araraquara, UNESP, Araraquara/SP, the results of the serological tests for toxoplasmosis in the prenatal care routine were analyzed in two groups of patients. One consisting of pregnant women with negative T. gondiispecific IgM (n=200) and the other consisting of pregnant women with positive T. gondii-specific IgM (n=33). The T. gondii-specific IgG avidity test was performed in the group with positive T. gondii-specific IgM. Results: Most pregnant women (76.9%) who presented intermediate avidity test results received antiparasitic treatment. Of the 16 pregnant women who presented high avidity results, nine (56,25%) received antiparasitic treatment. Conclusions: Even in the presence of a high specific- T. gondii IgG avidity test in the first trimester of gestation, the antiparasitic treatment was instituted, demonstrating that the avidity test was not adequately utilized in the clinical practice. KEY WORDS: TOXOPLASMOSIS, CONGENITAL/PREVENTION & CONTROL; TOXOPLASMA/IMMUNOLOGY; ANTIBODY AFFINITY; SEROLOGIC TESTS; IMUNOGLOBULIN G/ANALYSIS; PRENATAL CARE; CROSS-SECTIONAL STUDIES. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-09-27 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Estudo diagnóstico |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1636 |
url |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1636 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1636/1899 https://revistaseletronicas.pucrs.br/scientiamedica/article/view/1636/7879 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
dc.source.none.fl_str_mv |
Scientia Medica; Vol. 17 No. 2 (2007); 57-62 Scientia Medica; v. 17 n. 2 (2007); 57-62 1980-6108 1806-5562 reponame:Scientia Medica (Porto Alegre. Online) instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Scientia Medica (Porto Alegre. Online) |
collection |
Scientia Medica (Porto Alegre. Online) |
repository.name.fl_str_mv |
Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
scientiamedica@pucrs.br || editora.periodicos@pucrs.br |
_version_ |
1809101748467400704 |