Validação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopia

Detalhes bibliográficos
Autor(a) principal: Branco, Larissa Lopes
Data de Publicação: 2018
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da PUC_RS
Texto Completo: http://tede2.pucrs.br/tede2/handle/tede/8447
Resumo: Parkinson’s disease (PD) is one of the most prevalent degenerative neurological diseases today. PD, dementia syndromes, and motor neuron disease are expected to surpass cancer as the leading cause of death among the elderly by 2040. Diseases associated with aging can cause significant swallowing impairments, known as dysphagia. A swallowing evaluation can be conducted through Videofluoroscopy (VFD), considered the gold standard of diagnostic methods, but this evaluation is not available in every health center. The clinical evaluation of swallowing is a subjective speech therapy evaluation procedure that depends on the examiner’s knowledge in order to adequately detect signs that suggest laryngeal and tracheal aspiration/penetration. With this in mind, this project’s goal is to verify the agreement between the findings of the clinical swallowing evaluation and the objective swallowing evaluation (VFD), as an initial step in the process of validating the clinical swallowing evaluation protocol Swallowing Clinical Assessment Score in Parkinson’s Disease SCAS-PD. Application of the SCAS-PD took place concurrently with the VFS test. The interclass correlation coefficient and the Kappa 5 by 5 coefficient were calculated. The calculation was made for the area of the Receiver Operating Characteristic (ROC) curve, and for the sensitivity and specificity for detection of PA. The internal consistency of the SCAS-PD was calculated using Cronbach's alpha. 31 subjects were tested (68.8±7.6 years old). The ROC curve for the SCAS-PD differentiating between normal/functional and low, moderate and severe levels of dysphagia, AUC: 0.97; IC 95%: 0.92-1.00; sensitivity: 100% and specificity of 87.5%. The internal consistency was α = 0.91 for the total score. The internal consistency of the SCAS-PD domains was calculated; oral phase α = 0.73, pharyngeal phase α= 0.86, and signs of PA α = 0.95. SCAS-PD has been demonstrated to be a sensitive and specific screening tool for the detection of dysphagia and detection of the clinical signs of laryngotracheal PA.
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spelling Loureiro, Fernanda Soareshttp://lattes.cnpq.br/8040680068992017Schwanke, Carla Helena Augustinhttp://lattes.cnpq.br/2584101236741703http://lattes.cnpq.br/0683993076185177Branco, Larissa Lopes2019-02-13T12:21:55Z2018-03-13http://tede2.pucrs.br/tede2/handle/tede/8447Parkinson’s disease (PD) is one of the most prevalent degenerative neurological diseases today. PD, dementia syndromes, and motor neuron disease are expected to surpass cancer as the leading cause of death among the elderly by 2040. Diseases associated with aging can cause significant swallowing impairments, known as dysphagia. A swallowing evaluation can be conducted through Videofluoroscopy (VFD), considered the gold standard of diagnostic methods, but this evaluation is not available in every health center. The clinical evaluation of swallowing is a subjective speech therapy evaluation procedure that depends on the examiner’s knowledge in order to adequately detect signs that suggest laryngeal and tracheal aspiration/penetration. With this in mind, this project’s goal is to verify the agreement between the findings of the clinical swallowing evaluation and the objective swallowing evaluation (VFD), as an initial step in the process of validating the clinical swallowing evaluation protocol Swallowing Clinical Assessment Score in Parkinson’s Disease SCAS-PD. Application of the SCAS-PD took place concurrently with the VFS test. The interclass correlation coefficient and the Kappa 5 by 5 coefficient were calculated. The calculation was made for the area of the Receiver Operating Characteristic (ROC) curve, and for the sensitivity and specificity for detection of PA. The internal consistency of the SCAS-PD was calculated using Cronbach's alpha. 31 subjects were tested (68.8±7.6 years old). The ROC curve for the SCAS-PD differentiating between normal/functional and low, moderate and severe levels of dysphagia, AUC: 0.97; IC 95%: 0.92-1.00; sensitivity: 100% and specificity of 87.5%. The internal consistency was α = 0.91 for the total score. The internal consistency of the SCAS-PD domains was calculated; oral phase α = 0.73, pharyngeal phase α= 0.86, and signs of PA α = 0.95. SCAS-PD has been demonstrated to be a sensitive and specific screening tool for the detection of dysphagia and detection of the clinical signs of laryngotracheal PA.A doença de Parkinson (DP) é uma das doenças neurodegenerativas mais prevalentes nos dias de hoje. A DP, as síndromes demenciais e a doença do neurônio motor devem superar o câncer como causa de morte dos idosos em 2040. Doenças comuns ao envelhecimento podem causar distúrbios de deglutição importantes, denominados disfagia. A avaliação da deglutição pode ser realizada através da videofluoroscopia da deglutição (VFD), considerada como método diagnóstico padrão-ouro para detecção de disfagia, porém este exame não está disponível em todos os centros de saúde. A avalição clínica da deglutição é um procedimento de avaliação fonoaudiológica subjetivo, que depende do conhecimento do examinador para realizar a detecção dos sinais sugestivos de aspiração/penetração laringotraqueal. Este estudo teve como objetivo a validação do protocolo de avaliação clínica da deglutição Swallowing Clinical Assessment Score in Parkinson’s Disease (SCAS-PD) através da concordância dos achados da avaliação clínica com a avaliação objetiva pela VFD. Para isso, foram avaliados 31 indivíduos (68,8±7,6 anos), que realizaram acompanhamento no ambulatório de distúrbios do movimento no serviço de Neurologia do Hospital São Lucas da PUCRS e que foram encaminhados para realizar o exame de VFD no setor de radiologia do mesmo hospital. A avaliação clínica do SCAS-PD foi realizada concomitante ao exame objetivo de VFD. Foi calculado o coeficiente de Correlação Intraclasse de 5 por 5 para a análise de concordância entre os níveis de severidade do SCAS-PD e a escala de severidade do protocolo do exame da VFD. A curva Receiver Operating Characteristic (ROC) do SCAS-PD que diferenciou entre normal/ funcional e os níveis de disfagia leve, moderado e severo teve como resultado AUC: 0,97; IC 95%: 0,92-1,00; sensibilidade: 100% e especificidade de 87,5%. O SCAS-PD teve boa consistência interna com α = 0,91. Também apresentou boa confiabilidade para cada domínio avaliado: fase oral α = 0,73, fase faríngea α= 0,86, e sinais de penetração e aspiração α = 0,95. O instrumento SCAS-PD demonstrou ser válido para o rastreio da disfagia, sendo sensível e específico para a detecção dos sinais clínicos de aspiração e/ou penetração laringotraqueal em indivíduos com DP.Submitted by PPG Gerontologia Biomédica (geronbio@pucrs.br) on 2019-02-11T16:05:34Z No. of bitstreams: 1 BRANCO_LARISSA_ LOPES_DIS.pdf: 2037682 bytes, checksum: 66e9f45a4607a953f8d8c3fc17de0cb0 (MD5)Approved for entry into archive by Sheila Dias (sheila.dias@pucrs.br) on 2019-02-13T12:14:19Z (GMT) No. of bitstreams: 1 BRANCO_LARISSA_ LOPES_DIS.pdf: 2037682 bytes, checksum: 66e9f45a4607a953f8d8c3fc17de0cb0 (MD5)Made available in DSpace on 2019-02-13T12:21:55Z (GMT). No. of bitstreams: 1 BRANCO_LARISSA_ LOPES_DIS.pdf: 2037682 bytes, checksum: 66e9f45a4607a953f8d8c3fc17de0cb0 (MD5) Previous issue date: 2018-03-13Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfhttp://tede2.pucrs.br:80/tede2/retrieve/174107/BRANCO_LARISSA_%20LOPES_DIS.pdf.jpgporPontifícia Universidade Católica do Rio Grande do SulPrograma de Pós-Graduação em Gerontologia BiomédicaPUCRSBrasilEscola de MedicinaParkinsonDisfagiaAvaliação ClínicaVideofluoroscopiaCIENCIAS DA SAUDE::MEDICINAValidação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisTrabalho não apresenta restrição para publicação8969645070886364160500600500600-224747486637135387-9693694523087866273590462550136975366info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da PUC_RSinstname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSTHUMBNAILBRANCO_LARISSA_ LOPES_DIS.pdf.jpgBRANCO_LARISSA_ LOPES_DIS.pdf.jpgimage/jpeg5949http://tede2.pucrs.br/tede2/bitstream/tede/8447/4/BRANCO_LARISSA_+LOPES_DIS.pdf.jpg36e459d63cbb3d313139f134db42bb98MD54TEXTBRANCO_LARISSA_ LOPES_DIS.pdf.txtBRANCO_LARISSA_ LOPES_DIS.pdf.txttext/plain101776http://tede2.pucrs.br/tede2/bitstream/tede/8447/3/BRANCO_LARISSA_+LOPES_DIS.pdf.txt162f8c53af665c12825568d3ab85a7bfMD53ORIGINALBRANCO_LARISSA_ LOPES_DIS.pdfBRANCO_LARISSA_ LOPES_DIS.pdfapplication/pdf2037682http://tede2.pucrs.br/tede2/bitstream/tede/8447/2/BRANCO_LARISSA_+LOPES_DIS.pdf66e9f45a4607a953f8d8c3fc17de0cb0MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8590http://tede2.pucrs.br/tede2/bitstream/tede/8447/1/license.txt220e11f2d3ba5354f917c7035aadef24MD51tede/84472019-02-13 12:00:32.086oai:tede2.pucrs.br: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede2.pucrs.br/tede2/PRIhttps://tede2.pucrs.br/oai/requestbiblioteca.central@pucrs.br||opendoar:2019-02-13T14:00:32Biblioteca Digital de Teses e Dissertações da PUC_RS - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.por.fl_str_mv Validação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopia
title Validação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopia
spellingShingle Validação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopia
Branco, Larissa Lopes
Parkinson
Disfagia
Avaliação Clínica
Videofluoroscopia
CIENCIAS DA SAUDE::MEDICINA
title_short Validação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopia
title_full Validação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopia
title_fullStr Validação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopia
title_full_unstemmed Validação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopia
title_sort Validação do protocolo de avaliação clínica da deglutição swallowing clinical assessment score in parkinson’s disease (Scas-Pd) em comparação com o exame objetivo de videofluoroscopia
author Branco, Larissa Lopes
author_facet Branco, Larissa Lopes
author_role author
dc.contributor.advisor1.fl_str_mv Loureiro, Fernanda Soares
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/8040680068992017
dc.contributor.advisor-co1.fl_str_mv Schwanke, Carla Helena Augustin
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/2584101236741703
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/0683993076185177
dc.contributor.author.fl_str_mv Branco, Larissa Lopes
contributor_str_mv Loureiro, Fernanda Soares
Schwanke, Carla Helena Augustin
dc.subject.por.fl_str_mv Parkinson
Disfagia
Avaliação Clínica
Videofluoroscopia
topic Parkinson
Disfagia
Avaliação Clínica
Videofluoroscopia
CIENCIAS DA SAUDE::MEDICINA
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::MEDICINA
description Parkinson’s disease (PD) is one of the most prevalent degenerative neurological diseases today. PD, dementia syndromes, and motor neuron disease are expected to surpass cancer as the leading cause of death among the elderly by 2040. Diseases associated with aging can cause significant swallowing impairments, known as dysphagia. A swallowing evaluation can be conducted through Videofluoroscopy (VFD), considered the gold standard of diagnostic methods, but this evaluation is not available in every health center. The clinical evaluation of swallowing is a subjective speech therapy evaluation procedure that depends on the examiner’s knowledge in order to adequately detect signs that suggest laryngeal and tracheal aspiration/penetration. With this in mind, this project’s goal is to verify the agreement between the findings of the clinical swallowing evaluation and the objective swallowing evaluation (VFD), as an initial step in the process of validating the clinical swallowing evaluation protocol Swallowing Clinical Assessment Score in Parkinson’s Disease SCAS-PD. Application of the SCAS-PD took place concurrently with the VFS test. The interclass correlation coefficient and the Kappa 5 by 5 coefficient were calculated. The calculation was made for the area of the Receiver Operating Characteristic (ROC) curve, and for the sensitivity and specificity for detection of PA. The internal consistency of the SCAS-PD was calculated using Cronbach's alpha. 31 subjects were tested (68.8±7.6 years old). The ROC curve for the SCAS-PD differentiating between normal/functional and low, moderate and severe levels of dysphagia, AUC: 0.97; IC 95%: 0.92-1.00; sensitivity: 100% and specificity of 87.5%. The internal consistency was α = 0.91 for the total score. The internal consistency of the SCAS-PD domains was calculated; oral phase α = 0.73, pharyngeal phase α= 0.86, and signs of PA α = 0.95. SCAS-PD has been demonstrated to be a sensitive and specific screening tool for the detection of dysphagia and detection of the clinical signs of laryngotracheal PA.
publishDate 2018
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