Levels of TBT and other selected organotin compounds in duplicate diet samples
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.6/9436 |
Resumo: | Organotin compounds (OTs) are ubiquitous contaminants with a broad range of applications ranging from biocides and pesticides to catalysts for the production of polyurethane foams and silicones. The deleterious effects of some OTs (particularly tributyltin - TBT) upon wildlife and experimental animals are well documented and include endocrine disruption, immunotoxicity, neurotoxicity, genotoxicity and metabolic dysfunction in which obesity is included. However, virtually no data on the current human exposure levels is available. In order to bridge this gap, we quantified for the first time the levels of OTs in duplicate diet samples from members of the University of Aveiro in Portugal. OTs were detected in 32% of the 28 diet samples analyzed, at relatively low levels. TBT and monobutyltin were detected only in two samples and dibutyltin was detectable in three samples. Dioctyltin was quantified in four samples and monooctyltin in three samples. Phenyltins were below the detection limit in all the diet samples analyzed. Overall, for the vast majority of the samples (89%), the estimated daily intakes (EDI) of organotins through food were much lower than the established tolerable daily intakes (TDI). Hence, for the majority of the participants the risk associated with food ingestion is low. |
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Levels of TBT and other selected organotin compounds in duplicate diet samplesEnvironmental MonitoringHumansOrganotin CompoundsPortugalTrialkyltin CompoundsDietDietary ExposureOrganotin compounds (OTs) are ubiquitous contaminants with a broad range of applications ranging from biocides and pesticides to catalysts for the production of polyurethane foams and silicones. The deleterious effects of some OTs (particularly tributyltin - TBT) upon wildlife and experimental animals are well documented and include endocrine disruption, immunotoxicity, neurotoxicity, genotoxicity and metabolic dysfunction in which obesity is included. However, virtually no data on the current human exposure levels is available. In order to bridge this gap, we quantified for the first time the levels of OTs in duplicate diet samples from members of the University of Aveiro in Portugal. OTs were detected in 32% of the 28 diet samples analyzed, at relatively low levels. TBT and monobutyltin were detected only in two samples and dibutyltin was detectable in three samples. Dioctyltin was quantified in four samples and monooctyltin in three samples. Phenyltins were below the detection limit in all the diet samples analyzed. Overall, for the vast majority of the samples (89%), the estimated daily intakes (EDI) of organotins through food were much lower than the established tolerable daily intakes (TDI). Hence, for the majority of the participants the risk associated with food ingestion is low.ElsevieruBibliorumSousa, Ana C. A.Coelho, SóniaPastorinho, M. RamiroTaborda Barata, LuisNogueira, António J.A.Isobe, TomohikoKunisue, TatsuyaTakahashi, ShinTanabe, Shinsuke2020-02-21T10:49:04Z2017-01-012017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/9436eng10.1016/j.scitotenv.2016.09.037metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-15T09:50:27Zoai:ubibliorum.ubi.pt:10400.6/9436Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:49:32.942108Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Levels of TBT and other selected organotin compounds in duplicate diet samples |
title |
Levels of TBT and other selected organotin compounds in duplicate diet samples |
spellingShingle |
Levels of TBT and other selected organotin compounds in duplicate diet samples Sousa, Ana C. A. Environmental Monitoring Humans Organotin Compounds Portugal Trialkyltin Compounds Diet Dietary Exposure |
title_short |
Levels of TBT and other selected organotin compounds in duplicate diet samples |
title_full |
Levels of TBT and other selected organotin compounds in duplicate diet samples |
title_fullStr |
Levels of TBT and other selected organotin compounds in duplicate diet samples |
title_full_unstemmed |
Levels of TBT and other selected organotin compounds in duplicate diet samples |
title_sort |
Levels of TBT and other selected organotin compounds in duplicate diet samples |
author |
Sousa, Ana C. A. |
author_facet |
Sousa, Ana C. A. Coelho, Sónia Pastorinho, M. Ramiro Taborda Barata, Luis Nogueira, António J.A. Isobe, Tomohiko Kunisue, Tatsuya Takahashi, Shin Tanabe, Shinsuke |
author_role |
author |
author2 |
Coelho, Sónia Pastorinho, M. Ramiro Taborda Barata, Luis Nogueira, António J.A. Isobe, Tomohiko Kunisue, Tatsuya Takahashi, Shin Tanabe, Shinsuke |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
uBibliorum |
dc.contributor.author.fl_str_mv |
Sousa, Ana C. A. Coelho, Sónia Pastorinho, M. Ramiro Taborda Barata, Luis Nogueira, António J.A. Isobe, Tomohiko Kunisue, Tatsuya Takahashi, Shin Tanabe, Shinsuke |
dc.subject.por.fl_str_mv |
Environmental Monitoring Humans Organotin Compounds Portugal Trialkyltin Compounds Diet Dietary Exposure |
topic |
Environmental Monitoring Humans Organotin Compounds Portugal Trialkyltin Compounds Diet Dietary Exposure |
description |
Organotin compounds (OTs) are ubiquitous contaminants with a broad range of applications ranging from biocides and pesticides to catalysts for the production of polyurethane foams and silicones. The deleterious effects of some OTs (particularly tributyltin - TBT) upon wildlife and experimental animals are well documented and include endocrine disruption, immunotoxicity, neurotoxicity, genotoxicity and metabolic dysfunction in which obesity is included. However, virtually no data on the current human exposure levels is available. In order to bridge this gap, we quantified for the first time the levels of OTs in duplicate diet samples from members of the University of Aveiro in Portugal. OTs were detected in 32% of the 28 diet samples analyzed, at relatively low levels. TBT and monobutyltin were detected only in two samples and dibutyltin was detectable in three samples. Dioctyltin was quantified in four samples and monooctyltin in three samples. Phenyltins were below the detection limit in all the diet samples analyzed. Overall, for the vast majority of the samples (89%), the estimated daily intakes (EDI) of organotins through food were much lower than the established tolerable daily intakes (TDI). Hence, for the majority of the participants the risk associated with food ingestion is low. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 2017-01-01T00:00:00Z 2020-02-21T10:49:04Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.6/9436 |
url |
http://hdl.handle.net/10400.6/9436 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.scitotenv.2016.09.037 |
dc.rights.driver.fl_str_mv |
metadata only access info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
metadata only access |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799136387126001664 |