Spinal cord lesion by minor trauma as an early sign of multiple system atrophy

Detalhes bibliográficos
Autor(a) principal: Brum, Marisa
Data de Publicação: 2016
Outros Autores: Reimão, Sofia, Sousa, Djalma, de Carvalho, Rui, Ferreira, Joaquim J
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/50237
Resumo: Copyright: © 2016 Brum, Reimão, Sousa, de Carvalho and Ferreira. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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spelling Spinal cord lesion by minor trauma as an early sign of multiple system atrophyAtypical parkinsonismEarly signMultiple system atrophySpinal cord lesionTraumaCopyright: © 2016 Brum, Reimão, Sousa, de Carvalho and Ferreira. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.Multiple system atrophy (MSA) is characterized clinically by parkinsonism, cerebellar, autonomic, and corticospinal features of variable severity. When the presentation is only parkinsonism, the disease might be difficult to differentiate from Parkinson's disease (PD). We present a case of an 80-year-old man with previous diagnosis of PD. One year after the diagnosis, he had a whiplash cervical trauma due to a tricycle accident caused by a hole in the road. This low-energy trauma caused an unstable C4-C5 cervical fracture with spinal cord injury, which required surgical decompression and stabilization. Neurological examination showed marked postural instability, no rest and postural tremor, finger tapping slowed on the right, spastic tetraparesis (ASIA D) - predominantly on the left side, brisk deep tendon reflexes in the upper and lower extremities, and bilateral extensor plantar response. He also presented with vertical gaze restriction, mild hypometria in horizontal saccades, moderate dysphagia, and dysphonia. As atypical parkinsonism was suspected, he underwent an MRI that revealed conjunction of findings suggestive of parkinsonian-type MSA. In our case, we hypothesize that the loss of postural reflexes, as an early manifestation of MSA, did not allow the patient to have an effective reaction response to a low-energy trauma, resulting in a more severe injury. With this case report, we speculate that the severe spinal lesions caused by minor accidents can be an early sign of postural instability, which may lead to clinical suspicion of neurodegenerative disorder manifested by postural reflexes impairment.FrontiersRepositório da Universidade de LisboaBrum, MarisaReimão, SofiaSousa, Djalmade Carvalho, RuiFerreira, Joaquim J2021-12-02T12:11:53Z20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/50237engFront Neurol. 2016 Mar 14;7:3310.3389/fneur.2016.000331664-2295info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:54:14Zoai:repositorio.ul.pt:10451/50237Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:01:40.820389Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Spinal cord lesion by minor trauma as an early sign of multiple system atrophy
title Spinal cord lesion by minor trauma as an early sign of multiple system atrophy
spellingShingle Spinal cord lesion by minor trauma as an early sign of multiple system atrophy
Brum, Marisa
Atypical parkinsonism
Early sign
Multiple system atrophy
Spinal cord lesion
Trauma
title_short Spinal cord lesion by minor trauma as an early sign of multiple system atrophy
title_full Spinal cord lesion by minor trauma as an early sign of multiple system atrophy
title_fullStr Spinal cord lesion by minor trauma as an early sign of multiple system atrophy
title_full_unstemmed Spinal cord lesion by minor trauma as an early sign of multiple system atrophy
title_sort Spinal cord lesion by minor trauma as an early sign of multiple system atrophy
author Brum, Marisa
author_facet Brum, Marisa
Reimão, Sofia
Sousa, Djalma
de Carvalho, Rui
Ferreira, Joaquim J
author_role author
author2 Reimão, Sofia
Sousa, Djalma
de Carvalho, Rui
Ferreira, Joaquim J
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Brum, Marisa
Reimão, Sofia
Sousa, Djalma
de Carvalho, Rui
Ferreira, Joaquim J
dc.subject.por.fl_str_mv Atypical parkinsonism
Early sign
Multiple system atrophy
Spinal cord lesion
Trauma
topic Atypical parkinsonism
Early sign
Multiple system atrophy
Spinal cord lesion
Trauma
description Copyright: © 2016 Brum, Reimão, Sousa, de Carvalho and Ferreira. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
publishDate 2016
dc.date.none.fl_str_mv 2016
2016-01-01T00:00:00Z
2021-12-02T12:11:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/50237
url http://hdl.handle.net/10451/50237
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Front Neurol. 2016 Mar 14;7:33
10.3389/fneur.2016.00033
1664-2295
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers
publisher.none.fl_str_mv Frontiers
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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