Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothers
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/150730 |
Resumo: | We would like to thank all women who participated in this study. Grant PCIN-2017-012 funded by MCIN/AEI/ 10.13039/501100011033 and cofunded by the “European Union”. JR acknowledge Grant IJC 2018-035126-I funded by MCIN/AEI/ 10.13039/501100011033 and by “ESF Investing in your future”. MAM was granted with Sara Borell fellowship by Instituto de Salud Carlos III (CD21/00045). We thank Antonio Pino, from the Metabolomics facility of the Centre for Omic Sciences (COS) Joint Unit of the Universitat Rovira i Virgili-Eurecat, for their contribution to chlorpyrifos analysis. The Portuguese Foundation for Science and Technology supported the Ph.D. Grant of IM (DFA/BD/4413/2020). AgriFood XXI R&D&I project, operation No. 708 NORTE-01-0145-FEDER-000041, co-financed by the European Regional Development Fund 709 (ERDF) through NORTH 2020 (Northern Regional Operational Program 2014/2020). Sara C. Cunha acknowledges FCT for IF/01616/2015 contract. Publisher Copyright: © 2022 |
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Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothersBreast milkEarly life exposureEndocrine disruptorsHuman biomonitoringNeurotoxicityPesticidesPOPsEnvironmental Science(all)SDG 3 - Good Health and Well-beingWe would like to thank all women who participated in this study. Grant PCIN-2017-012 funded by MCIN/AEI/ 10.13039/501100011033 and cofunded by the “European Union”. JR acknowledge Grant IJC 2018-035126-I funded by MCIN/AEI/ 10.13039/501100011033 and by “ESF Investing in your future”. MAM was granted with Sara Borell fellowship by Instituto de Salud Carlos III (CD21/00045). We thank Antonio Pino, from the Metabolomics facility of the Centre for Omic Sciences (COS) Joint Unit of the Universitat Rovira i Virgili-Eurecat, for their contribution to chlorpyrifos analysis. The Portuguese Foundation for Science and Technology supported the Ph.D. Grant of IM (DFA/BD/4413/2020). AgriFood XXI R&D&I project, operation No. 708 NORTE-01-0145-FEDER-000041, co-financed by the European Regional Development Fund 709 (ERDF) through NORTH 2020 (Northern Regional Operational Program 2014/2020). Sara C. Cunha acknowledges FCT for IF/01616/2015 contract. Publisher Copyright: © 2022Breastfeeding is one of the most effective ways to ensure child health and survival, with several benefits for both the infants and their mothers. However, breast milk can contain environmental pollutants with endocrine disruption capacity, neurotoxicity and/or potential to alter microbiota. Monitoring breast milk provides information on the current chemical exposure of breastfed infants and, in addition, on the current and historical exposure of nursing mothers. In this study, the levels of a wide range of pollutants were measured in breast milk of Spanish nursing mothers. Target chemicals were dichlorodiphenyltrichloroethane (DDT), dichlorodiphenyldichloroethylene (DDE), hexachlorobenzene (HCB), oxy-chlordane, polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), per- and poly-fluoroalkyl substances (PFASs) (including perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA)), chlorpyrifos, bisphenol A (BPA), tetrabromobisphenol A (TBBPA), and a number of toxic and essential elements. Traces of most chemicals were found. A correlation between the levels of some persistent organic pollutants (POPs) and maternal characteristics (age and body mass index) was observed, while smoking was associated to higher concentrations of some toxic elements. Higher levels of PCBs were detected in samples from Spanish primiparous mothers compared to non-Spanish multiparous women. Breast milk from low-income mothers showed higher content of DDT and DDE than high-income mothers. Although breastfeeding is clearly beneficial for babies, the exposure to this mixture of hazardous substances, as well as their interaction and combined effects must not be disregarded.UCIBIO - Applied Molecular Biosciences UnitDQ - Departamento de QuímicaRUNRovira, JoaquimMartínez, María ÁngelesMari, MontseCunha, Sara CristinaFernandes, José OliveiraMarmelo, IsaMarques, AntónioHaug, Line SmåstuenThomsen, CathrineNadal, MartíDomingo, José L.Schuhmacher, Marta2023-03-16T22:38:27Z2022-082022-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article13application/pdfhttp://hdl.handle.net/10362/150730eng0160-4120PURE: 56117645https://doi.org/10.1016/j.envint.2022.107375info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:33:04Zoai:run.unl.pt:10362/150730Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:54:17.207525Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothers |
| title |
Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothers |
| spellingShingle |
Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothers Rovira, Joaquim Breast milk Early life exposure Endocrine disruptors Human biomonitoring Neurotoxicity Pesticides POPs Environmental Science(all) SDG 3 - Good Health and Well-being |
| title_short |
Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothers |
| title_full |
Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothers |
| title_fullStr |
Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothers |
| title_full_unstemmed |
Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothers |
| title_sort |
Mixture of environmental pollutants in breast milk from a Spanish cohort of nursing mothers |
| author |
Rovira, Joaquim |
| author_facet |
Rovira, Joaquim Martínez, María Ángeles Mari, Montse Cunha, Sara Cristina Fernandes, José Oliveira Marmelo, Isa Marques, António Haug, Line Småstuen Thomsen, Cathrine Nadal, Martí Domingo, José L. Schuhmacher, Marta |
| author_role |
author |
| author2 |
Martínez, María Ángeles Mari, Montse Cunha, Sara Cristina Fernandes, José Oliveira Marmelo, Isa Marques, António Haug, Line Småstuen Thomsen, Cathrine Nadal, Martí Domingo, José L. Schuhmacher, Marta |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
UCIBIO - Applied Molecular Biosciences Unit DQ - Departamento de Química RUN |
| dc.contributor.author.fl_str_mv |
Rovira, Joaquim Martínez, María Ángeles Mari, Montse Cunha, Sara Cristina Fernandes, José Oliveira Marmelo, Isa Marques, António Haug, Line Småstuen Thomsen, Cathrine Nadal, Martí Domingo, José L. Schuhmacher, Marta |
| dc.subject.por.fl_str_mv |
Breast milk Early life exposure Endocrine disruptors Human biomonitoring Neurotoxicity Pesticides POPs Environmental Science(all) SDG 3 - Good Health and Well-being |
| topic |
Breast milk Early life exposure Endocrine disruptors Human biomonitoring Neurotoxicity Pesticides POPs Environmental Science(all) SDG 3 - Good Health and Well-being |
| description |
We would like to thank all women who participated in this study. Grant PCIN-2017-012 funded by MCIN/AEI/ 10.13039/501100011033 and cofunded by the “European Union”. JR acknowledge Grant IJC 2018-035126-I funded by MCIN/AEI/ 10.13039/501100011033 and by “ESF Investing in your future”. MAM was granted with Sara Borell fellowship by Instituto de Salud Carlos III (CD21/00045). We thank Antonio Pino, from the Metabolomics facility of the Centre for Omic Sciences (COS) Joint Unit of the Universitat Rovira i Virgili-Eurecat, for their contribution to chlorpyrifos analysis. The Portuguese Foundation for Science and Technology supported the Ph.D. Grant of IM (DFA/BD/4413/2020). AgriFood XXI R&D&I project, operation No. 708 NORTE-01-0145-FEDER-000041, co-financed by the European Regional Development Fund 709 (ERDF) through NORTH 2020 (Northern Regional Operational Program 2014/2020). Sara C. Cunha acknowledges FCT for IF/01616/2015 contract. Publisher Copyright: © 2022 |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-08 2022-08-01T00:00:00Z 2023-03-16T22:38:27Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10362/150730 |
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http://hdl.handle.net/10362/150730 |
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eng |
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eng |
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0160-4120 PURE: 56117645 https://doi.org/10.1016/j.envint.2022.107375 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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13 application/pdf |
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