I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin

Detalhes bibliográficos
Autor(a) principal: Brandão, Pedro
Data de Publicação: 2020
Outros Autores: Pinheiro, Daniela, Melo, J. Sérgio Seixas de, Pineiro, Marta
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
DOI: 10.1016/j.dyepig.2019.107935
Texto Completo: http://hdl.handle.net/10316/93147
https://doi.org/10.1016/j.dyepig.2019.107935
Resumo: Tryptanthrin, a product present in several natural sources used as colorants and very relevant in the field of Medicinal Chemistry, was synthesized from indigo and isatin under mild conditions using microwave irradiation. A plausible mechanism for the synthesis of tryptanthrin using the oxidant system formed by iodine, sodium hydride and DMF, the latter acting with dual activity as solvent and as the oxygen source, is proposed.
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spelling I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatinTryptanthrinDMFIsatinIndigoOxidationTryptanthrin, a product present in several natural sources used as colorants and very relevant in the field of Medicinal Chemistry, was synthesized from indigo and isatin under mild conditions using microwave irradiation. A plausible mechanism for the synthesis of tryptanthrin using the oxidant system formed by iodine, sodium hydride and DMF, the latter acting with dual activity as solvent and as the oxygen source, is proposed.2020info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/93147http://hdl.handle.net/10316/93147https://doi.org/10.1016/j.dyepig.2019.107935eng01437208https://www.sciencedirect.com/science/article/pii/S0143720819320340Brandão, PedroPinheiro, DanielaMelo, J. Sérgio Seixas dePineiro, Martainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-05-25T06:21:44Zoai:estudogeral.uc.pt:10316/93147Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:12:07.768882Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
title I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
spellingShingle I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
Brandão, Pedro
Tryptanthrin
DMF
Isatin
Indigo
Oxidation
Brandão, Pedro
Tryptanthrin
DMF
Isatin
Indigo
Oxidation
title_short I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
title_full I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
title_fullStr I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
title_full_unstemmed I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
title_sort I2/NaH/DMF as oxidant trio for the synthesis of tryptanthrin from indigo or isatin
author Brandão, Pedro
author_facet Brandão, Pedro
Brandão, Pedro
Pinheiro, Daniela
Melo, J. Sérgio Seixas de
Pineiro, Marta
Pinheiro, Daniela
Melo, J. Sérgio Seixas de
Pineiro, Marta
author_role author
author2 Pinheiro, Daniela
Melo, J. Sérgio Seixas de
Pineiro, Marta
author2_role author
author
author
dc.contributor.author.fl_str_mv Brandão, Pedro
Pinheiro, Daniela
Melo, J. Sérgio Seixas de
Pineiro, Marta
dc.subject.por.fl_str_mv Tryptanthrin
DMF
Isatin
Indigo
Oxidation
topic Tryptanthrin
DMF
Isatin
Indigo
Oxidation
description Tryptanthrin, a product present in several natural sources used as colorants and very relevant in the field of Medicinal Chemistry, was synthesized from indigo and isatin under mild conditions using microwave irradiation. A plausible mechanism for the synthesis of tryptanthrin using the oxidant system formed by iodine, sodium hydride and DMF, the latter acting with dual activity as solvent and as the oxygen source, is proposed.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/93147
http://hdl.handle.net/10316/93147
https://doi.org/10.1016/j.dyepig.2019.107935
url http://hdl.handle.net/10316/93147
https://doi.org/10.1016/j.dyepig.2019.107935
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 01437208
https://www.sciencedirect.com/science/article/pii/S0143720819320340
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instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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dc.identifier.doi.none.fl_str_mv 10.1016/j.dyepig.2019.107935

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