Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in Portugal

Detalhes bibliográficos
Autor(a) principal: Pinto, Miguel
Data de Publicação: 2020
Outros Autores: Rodrigues, João Carlos, Matias, Rui, Água-Doce, Ivone, Cordeiro, Dora, Correia, Cristina, Gomes, João Paulo, Borrego, Maria José, PTGonoNet
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/7333
Resumo: PTGonoNet: Filipa Alegria, Ana Jacinta Piedade, Maria Beatriz Tomaz, Cristina Toscano, Mariana Pessanha, Eliana Costa, Agostinho Lira, Catarina Chaves, Ana Cristina Silva, Margarida Feijó Pinto, Manuela Ribeiro, Angélica Costa Ramos, Hugo Cruz, Maria Helena Ramos, José Melo Cristino, Maria Inês Stilwell, Carlos Marques, Mariana Garcez, Maritza Pereira, Vera Santos, Marco Amaral, Maria José Rego de Sousa, Maria Favila Menezes, Elsa Calado, Luís Dias, Florbela Pereira, Idalina Rocha, Paula Mota Vieira, Maria Alberta Faustino, Maria Carmen Iglesias, Rita Pinto, Lúcia Serpa, Adriana Coutinho, Filomena Caldeira, José Diogo, Luísa Sancho, Sandra Schafer, José Carlos Camisão, Graça Trigueiro, Alexandra Costa, Alda Campos, Alexandra Pereira, Ana Catarina Guerreiro, Gizela Santos, Mónica Cardoso, Filomena Lencastre, Luísa Frazão, Sofia Soares, Inês Figueiredo, Vitória Rodrigues, Eugénio Corrêa, Rui Campainha, Maria Rosário Barros, Sofia Botelho Moniz.
id RCAP_03854d8cd446180e5e1362fd2046bd73
oai_identifier_str oai:repositorio.insa.pt:10400.18/7333
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in PortugalNeisseria gonorrhoeaeN. gonorrhoeaeNeisseria gonorrhoeae Antimicrobial Resistance (AMR)Antimicrobial ResistanceCollectionSexually Transmitted InfectionSurveillanceInfecções Sexualmente TransmissíveisResistência aos AntimicrobianosPortugalPTGonoNet: Filipa Alegria, Ana Jacinta Piedade, Maria Beatriz Tomaz, Cristina Toscano, Mariana Pessanha, Eliana Costa, Agostinho Lira, Catarina Chaves, Ana Cristina Silva, Margarida Feijó Pinto, Manuela Ribeiro, Angélica Costa Ramos, Hugo Cruz, Maria Helena Ramos, José Melo Cristino, Maria Inês Stilwell, Carlos Marques, Mariana Garcez, Maritza Pereira, Vera Santos, Marco Amaral, Maria José Rego de Sousa, Maria Favila Menezes, Elsa Calado, Luís Dias, Florbela Pereira, Idalina Rocha, Paula Mota Vieira, Maria Alberta Faustino, Maria Carmen Iglesias, Rita Pinto, Lúcia Serpa, Adriana Coutinho, Filomena Caldeira, José Diogo, Luísa Sancho, Sandra Schafer, José Carlos Camisão, Graça Trigueiro, Alexandra Costa, Alda Campos, Alexandra Pereira, Ana Catarina Guerreiro, Gizela Santos, Mónica Cardoso, Filomena Lencastre, Luísa Frazão, Sofia Soares, Inês Figueiredo, Vitória Rodrigues, Eugénio Corrêa, Rui Campainha, Maria Rosário Barros, Sofia Botelho Moniz.Neisseria gonorrhoeae antimicrobial resistance (AMR) and gonorrhea disease burden remain major public health concerns worldwide. To contribute to the supranational demands to monitor and manage the spread of antimicrobial-resistant N. gonorrhoeae, the Portuguese NIH promoted the creation of the National Laboratory Network for Neisseria gonorrhoeae Collection (PTGonoNet). The present study reports the N. gonorrhoeae major AMR trends observed from 2003 up to 2018. All isolates described in the present study constitute the opportunistic ongoing N. gonorrhoeae isolate collection supported by the National Reference Laboratory for Sexually Transmitted Infections of the Portuguese NIH, enrolling strains isolated in 35 different public and private laboratories. Minimum inhibitory concentrations were determined using E-tests for azithromycin, benzylpenicillin, cefixime, ceftriaxone, ciprofloxacin, gentamicin, spectinomycin and tetracycline. Molecular typing was determined using NG-MAST. AMR data of 2596 country-spread isolates show that 87.67% of all N. gonorrhoeae isolates presented decreased susceptibility to at least one antimicrobial. A continuous decreased susceptibility and resistance to penicillin, tetracycline and ciprofloxacin can be observed along the years. However, no decreased susceptibility to cephalosporins was observed until 2018, while for azithromycin, this was always low. The most common observed NG-MAST genogroups were G1407, G7445, G225, G2, and G1034. This study evidences the advantages of a nationwide collection of isolates and of centralized AMR testing to respond to supranational (EURO-GASP) requirements while providing unprecedented data on AMR in the context of 15 years of surveillance.M. Pinto was supported by the Portuguese Science and Technology Foundation (FCT) through grant SFRH/BD/109264/2015.Springer/ European Society of Clinical MicrobiologyRepositório Científico do Instituto Nacional de SaúdePinto, MiguelRodrigues, João CarlosMatias, RuiÁgua-Doce, IvoneCordeiro, DoraCorreia, CristinaGomes, João PauloBorrego, Maria JoséPTGonoNet2021-03-05T15:26:22Z2020-092020-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/7333engEur J Clin Microbiol Infect Dis. 2020 Sep;39(9):1761-1770. doi: 10.1007/s10096-020-03907-7. Epub 2020 Jun 3.0934-972310.1007/s10096-020-03907-7info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:41:51Zoai:repositorio.insa.pt:10400.18/7333Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:41:50.735876Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in Portugal
title Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in Portugal
spellingShingle Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in Portugal
Pinto, Miguel
Neisseria gonorrhoeae
N. gonorrhoeae
Neisseria gonorrhoeae Antimicrobial Resistance (AMR)
Antimicrobial Resistance
Collection
Sexually Transmitted Infection
Surveillance
Infecções Sexualmente Transmissíveis
Resistência aos Antimicrobianos
Portugal
title_short Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in Portugal
title_full Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in Portugal
title_fullStr Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in Portugal
title_full_unstemmed Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in Portugal
title_sort Fifteen years of a nationwide culture collection of Neisseria gonorrhoeae antimicrobial resistance in Portugal
author Pinto, Miguel
author_facet Pinto, Miguel
Rodrigues, João Carlos
Matias, Rui
Água-Doce, Ivone
Cordeiro, Dora
Correia, Cristina
Gomes, João Paulo
Borrego, Maria José
PTGonoNet
author_role author
author2 Rodrigues, João Carlos
Matias, Rui
Água-Doce, Ivone
Cordeiro, Dora
Correia, Cristina
Gomes, João Paulo
Borrego, Maria José
PTGonoNet
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Pinto, Miguel
Rodrigues, João Carlos
Matias, Rui
Água-Doce, Ivone
Cordeiro, Dora
Correia, Cristina
Gomes, João Paulo
Borrego, Maria José
PTGonoNet
dc.subject.por.fl_str_mv Neisseria gonorrhoeae
N. gonorrhoeae
Neisseria gonorrhoeae Antimicrobial Resistance (AMR)
Antimicrobial Resistance
Collection
Sexually Transmitted Infection
Surveillance
Infecções Sexualmente Transmissíveis
Resistência aos Antimicrobianos
Portugal
topic Neisseria gonorrhoeae
N. gonorrhoeae
Neisseria gonorrhoeae Antimicrobial Resistance (AMR)
Antimicrobial Resistance
Collection
Sexually Transmitted Infection
Surveillance
Infecções Sexualmente Transmissíveis
Resistência aos Antimicrobianos
Portugal
description PTGonoNet: Filipa Alegria, Ana Jacinta Piedade, Maria Beatriz Tomaz, Cristina Toscano, Mariana Pessanha, Eliana Costa, Agostinho Lira, Catarina Chaves, Ana Cristina Silva, Margarida Feijó Pinto, Manuela Ribeiro, Angélica Costa Ramos, Hugo Cruz, Maria Helena Ramos, José Melo Cristino, Maria Inês Stilwell, Carlos Marques, Mariana Garcez, Maritza Pereira, Vera Santos, Marco Amaral, Maria José Rego de Sousa, Maria Favila Menezes, Elsa Calado, Luís Dias, Florbela Pereira, Idalina Rocha, Paula Mota Vieira, Maria Alberta Faustino, Maria Carmen Iglesias, Rita Pinto, Lúcia Serpa, Adriana Coutinho, Filomena Caldeira, José Diogo, Luísa Sancho, Sandra Schafer, José Carlos Camisão, Graça Trigueiro, Alexandra Costa, Alda Campos, Alexandra Pereira, Ana Catarina Guerreiro, Gizela Santos, Mónica Cardoso, Filomena Lencastre, Luísa Frazão, Sofia Soares, Inês Figueiredo, Vitória Rodrigues, Eugénio Corrêa, Rui Campainha, Maria Rosário Barros, Sofia Botelho Moniz.
publishDate 2020
dc.date.none.fl_str_mv 2020-09
2020-09-01T00:00:00Z
2021-03-05T15:26:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/7333
url http://hdl.handle.net/10400.18/7333
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Eur J Clin Microbiol Infect Dis. 2020 Sep;39(9):1761-1770. doi: 10.1007/s10096-020-03907-7. Epub 2020 Jun 3.
0934-9723
10.1007/s10096-020-03907-7
dc.rights.driver.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer/ European Society of Clinical Microbiology
publisher.none.fl_str_mv Springer/ European Society of Clinical Microbiology
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799132162803367936

Registros relacionados