Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo Registry
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10451/49627 |
Resumo: | Copyright © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
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Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo RegistryTakotsubo syndromeAtrial fibrillationBroken heart syndromeOutcomeCopyright © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.Background Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated in a large patient cohort. This study aimed to investigate the prevalence, clinical correlates, and prognostic impact of AF in patients with TTS. Methods and Results Patients with TTS were enrolled from the International Takotsubo Registry, which is a multinational network with 26 participating centers in Europe and the United States. Patients were dichotomized according to the presence or absence of AF at the time of admission. Of 1584 patients with TTS, 112 (7.1%) had AF. The mean age was higher (P<0.001), and there were fewer women (P=0.046) in the AF than in the non-AF group. Left ventricular ejection fraction was significantly lower (P=0.001), and cardiogenic shock was more often observed (P<0.001) in the AF group. Both in-hospital (P<0.001) and long-term mortality (P<0.001) were higher in the AF group. Multivariable Cox regression analysis revealed that AF was independently associated with higher long-term mortality (hazard ratio, 2.31; 95% CI, 1.50-3.55; P<0.001). Among patients with AF on admission, 42% had no known history of AF before the acute TTS event, and such patients had comparable in-hospital and long-term outcomes compared with those with a history of AF. Conclusions In patients presenting with TTS, AF on admission is significantly associated with increased in-hospital and long-term mortality rates. Whether antiarrhythmics and/or cardioversion are beneficial in TTS with AF should thus be tested in a future trial.Wiley BlackwellRepositório da Universidade de LisboaEl‐Battrawy, IbrahimCammann, Victoria L.Kato, KenSzawan, Konrad A.Di Vece, DavideRossi, AurelioWischnewsky, ManfredHermes‐Laufer, JuliaGili, SebastianoCitro, RodolfoBossone, EduardoAkin, IbrahimTemplin, ChristianNeuhaus, MichaelFranke, JenniferMeder, BenjaminJaguszewski, MiloszNoutsias, MichelKnorr, MaikeHeiner, SusanneD’Ascenzo, FabrizioDichtl, WolfgangBurgdorf, ChristofKherad, BehrouzTschöpe, CarstenSarcon, AnnahitaShinbane, JeroldRajan, LawrenceMichels, GuidoPfister, RomanCuneo, AlessandroJacobshagen, ClaudiusKarakas, MahirKoenig, WolfgangPott, AlexanderMeyer, PhilippeDavid Arroja, JoseBanning, AdrianCuculi, FlorimKobza, RichardFischer, Thomas A.Vasankari, TuijaAiraksinen, K. E. JuhaniNapp, L. ChristianBudnik, MonikaDworakowski, RafalMacCarthy, PhilipKaiser, ChristophOsswald, StefanGaliuto, LeonardaChan, ChristinaBridgman, PaulBeug, DanielDelmas, ClémentLairez, OlivierGilyarova, EkaterinaShilova, AlexandraGilyarov, MikhailKozel, MartinTousek, PetrWinchester, David E.Galuszka, JanUkena, ChristianPoglajen, GregorCarrilho-Ferreira, PedroHauck, ChristianPaolini, CarlaBilato, ClaudioKobayashi, YoshioPrasad, AbhiramRihal, Charanjit S.Liu, KanSchulze, P. ChristianBianco, MatteoJörg, LucasRickli, HansPestana, GonçaloNguyen, Thanh H.Böhm, MichaelMaier, Lars S.Pinto, Fausto J.Widimský, PetrFelix, Stephan B.Opolski, GrzegorzBraun‐Dullaeus, Ruediger C.Rottbauer, WolfgangHasenfuß, GerdPieske, Burkert M.Schunkert, HeribertThiele, HolgerBauersachs, JohannKatus, Hugo A.Horowitz, John D.Di Mario, CarloMünzel, ThomasCrea, FilippoBax, Jeroen J.Lüscher, Thomas F.Ruschitzka, FrankDuru, FiratBorggrefe, MartinGhadri, Jelena R.2021-09-24T17:25:08Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/49627engJ Am Heart Assoc. Aug 3;10(15):e01405910.1161/JAHA.119.0140592047-9980info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:53:34Zoai:repositorio.ul.pt:10451/49627Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:01:16.436294Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo Registry |
title |
Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo Registry |
spellingShingle |
Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo Registry El‐Battrawy, Ibrahim Takotsubo syndrome Atrial fibrillation Broken heart syndrome Outcome |
title_short |
Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo Registry |
title_full |
Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo Registry |
title_fullStr |
Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo Registry |
title_full_unstemmed |
Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo Registry |
title_sort |
Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the International Takotsubo Registry |
author |
El‐Battrawy, Ibrahim |
author_facet |
El‐Battrawy, Ibrahim Cammann, Victoria L. Kato, Ken Szawan, Konrad A. Di Vece, Davide Rossi, Aurelio Wischnewsky, Manfred Hermes‐Laufer, Julia Gili, Sebastiano Citro, Rodolfo Bossone, Eduardo Akin, Ibrahim Templin, Christian Neuhaus, Michael Franke, Jennifer Meder, Benjamin Jaguszewski, Milosz Noutsias, Michel Knorr, Maike Heiner, Susanne D’Ascenzo, Fabrizio Dichtl, Wolfgang Burgdorf, Christof Kherad, Behrouz Tschöpe, Carsten Sarcon, Annahita Shinbane, Jerold Rajan, Lawrence Michels, Guido Pfister, Roman Cuneo, Alessandro Jacobshagen, Claudius Karakas, Mahir Koenig, Wolfgang Pott, Alexander Meyer, Philippe David Arroja, Jose Banning, Adrian Cuculi, Florim Kobza, Richard Fischer, Thomas A. Vasankari, Tuija Airaksinen, K. E. Juhani Napp, L. Christian Budnik, Monika Dworakowski, Rafal MacCarthy, Philip Kaiser, Christoph Osswald, Stefan Galiuto, Leonarda Chan, Christina Bridgman, Paul Beug, Daniel Delmas, Clément Lairez, Olivier Gilyarova, Ekaterina Shilova, Alexandra Gilyarov, Mikhail Kozel, Martin Tousek, Petr Winchester, David E. Galuszka, Jan Ukena, Christian Poglajen, Gregor Carrilho-Ferreira, Pedro Hauck, Christian Paolini, Carla Bilato, Claudio Kobayashi, Yoshio Prasad, Abhiram Rihal, Charanjit S. Liu, Kan Schulze, P. Christian Bianco, Matteo Jörg, Lucas Rickli, Hans Pestana, Gonçalo Nguyen, Thanh H. Böhm, Michael Maier, Lars S. Pinto, Fausto J. Widimský, Petr Felix, Stephan B. Opolski, Grzegorz Braun‐Dullaeus, Ruediger C. Rottbauer, Wolfgang Hasenfuß, Gerd Pieske, Burkert M. Schunkert, Heribert Thiele, Holger Bauersachs, Johann Katus, Hugo A. Horowitz, John D. Di Mario, Carlo Münzel, Thomas Crea, Filippo Bax, Jeroen J. Lüscher, Thomas F. Ruschitzka, Frank Duru, Firat Borggrefe, Martin Ghadri, Jelena R. |
author_role |
author |
author2 |
Cammann, Victoria L. Kato, Ken Szawan, Konrad A. Di Vece, Davide Rossi, Aurelio Wischnewsky, Manfred Hermes‐Laufer, Julia Gili, Sebastiano Citro, Rodolfo Bossone, Eduardo Akin, Ibrahim Templin, Christian Neuhaus, Michael Franke, Jennifer Meder, Benjamin Jaguszewski, Milosz Noutsias, Michel Knorr, Maike Heiner, Susanne D’Ascenzo, Fabrizio Dichtl, Wolfgang Burgdorf, Christof Kherad, Behrouz Tschöpe, Carsten Sarcon, Annahita Shinbane, Jerold Rajan, Lawrence Michels, Guido Pfister, Roman Cuneo, Alessandro Jacobshagen, Claudius Karakas, Mahir Koenig, Wolfgang Pott, Alexander Meyer, Philippe David Arroja, Jose Banning, Adrian Cuculi, Florim Kobza, Richard Fischer, Thomas A. Vasankari, Tuija Airaksinen, K. E. Juhani Napp, L. Christian Budnik, Monika Dworakowski, Rafal MacCarthy, Philip Kaiser, Christoph Osswald, Stefan Galiuto, Leonarda Chan, Christina Bridgman, Paul Beug, Daniel Delmas, Clément Lairez, Olivier Gilyarova, Ekaterina Shilova, Alexandra Gilyarov, Mikhail Kozel, Martin Tousek, Petr Winchester, David E. Galuszka, Jan Ukena, Christian Poglajen, Gregor Carrilho-Ferreira, Pedro Hauck, Christian Paolini, Carla Bilato, Claudio Kobayashi, Yoshio Prasad, Abhiram Rihal, Charanjit S. Liu, Kan Schulze, P. Christian Bianco, Matteo Jörg, Lucas Rickli, Hans Pestana, Gonçalo Nguyen, Thanh H. Böhm, Michael Maier, Lars S. Pinto, Fausto J. Widimský, Petr Felix, Stephan B. Opolski, Grzegorz Braun‐Dullaeus, Ruediger C. Rottbauer, Wolfgang Hasenfuß, Gerd Pieske, Burkert M. Schunkert, Heribert Thiele, Holger Bauersachs, Johann Katus, Hugo A. Horowitz, John D. Di Mario, Carlo Münzel, Thomas Crea, Filippo Bax, Jeroen J. Lüscher, Thomas F. Ruschitzka, Frank Duru, Firat Borggrefe, Martin Ghadri, Jelena R. |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
El‐Battrawy, Ibrahim Cammann, Victoria L. Kato, Ken Szawan, Konrad A. Di Vece, Davide Rossi, Aurelio Wischnewsky, Manfred Hermes‐Laufer, Julia Gili, Sebastiano Citro, Rodolfo Bossone, Eduardo Akin, Ibrahim Templin, Christian Neuhaus, Michael Franke, Jennifer Meder, Benjamin Jaguszewski, Milosz Noutsias, Michel Knorr, Maike Heiner, Susanne D’Ascenzo, Fabrizio Dichtl, Wolfgang Burgdorf, Christof Kherad, Behrouz Tschöpe, Carsten Sarcon, Annahita Shinbane, Jerold Rajan, Lawrence Michels, Guido Pfister, Roman Cuneo, Alessandro Jacobshagen, Claudius Karakas, Mahir Koenig, Wolfgang Pott, Alexander Meyer, Philippe David Arroja, Jose Banning, Adrian Cuculi, Florim Kobza, Richard Fischer, Thomas A. Vasankari, Tuija Airaksinen, K. E. Juhani Napp, L. Christian Budnik, Monika Dworakowski, Rafal MacCarthy, Philip Kaiser, Christoph Osswald, Stefan Galiuto, Leonarda Chan, Christina Bridgman, Paul Beug, Daniel Delmas, Clément Lairez, Olivier Gilyarova, Ekaterina Shilova, Alexandra Gilyarov, Mikhail Kozel, Martin Tousek, Petr Winchester, David E. Galuszka, Jan Ukena, Christian Poglajen, Gregor Carrilho-Ferreira, Pedro Hauck, Christian Paolini, Carla Bilato, Claudio Kobayashi, Yoshio Prasad, Abhiram Rihal, Charanjit S. Liu, Kan Schulze, P. Christian Bianco, Matteo Jörg, Lucas Rickli, Hans Pestana, Gonçalo Nguyen, Thanh H. Böhm, Michael Maier, Lars S. Pinto, Fausto J. Widimský, Petr Felix, Stephan B. Opolski, Grzegorz Braun‐Dullaeus, Ruediger C. Rottbauer, Wolfgang Hasenfuß, Gerd Pieske, Burkert M. Schunkert, Heribert Thiele, Holger Bauersachs, Johann Katus, Hugo A. Horowitz, John D. Di Mario, Carlo Münzel, Thomas Crea, Filippo Bax, Jeroen J. Lüscher, Thomas F. Ruschitzka, Frank Duru, Firat Borggrefe, Martin Ghadri, Jelena R. |
dc.subject.por.fl_str_mv |
Takotsubo syndrome Atrial fibrillation Broken heart syndrome Outcome |
topic |
Takotsubo syndrome Atrial fibrillation Broken heart syndrome Outcome |
description |
Copyright © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-09-24T17:25:08Z 2021 2021-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/49627 |
url |
http://hdl.handle.net/10451/49627 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
J Am Heart Assoc. Aug 3;10(15):e014059 10.1161/JAHA.119.014059 2047-9980 |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley Blackwell |
publisher.none.fl_str_mv |
Wiley Blackwell |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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