Implementing human papillomavirus testing in a public health hospital : challenges and opportunities

Detalhes bibliográficos
Autor(a) principal: Beldi, Mariana Carmezim
Data de Publicação: 2012
Outros Autores: Tacla, Maricy, Caiaffa-Filho, Helio, Ab’Saber, Alexandre, Siqueira, Sheila, Baracat, Edmund Chada, Alves, Venâncio Avancini Ferreira, Longatto Filho, Adhemar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/23780
Resumo: Author's proof. The authors are indebted to Luciane Sarahyba and Nazareno dos Santos of the Molecular Biology Laboratory for their technical assistance.
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spelling Implementing human papillomavirus testing in a public health hospital : challenges and opportunitiesCytologyPap testHuman papillomavirus testingPrimary screeningScience & TechnologyAuthor's proof. The authors are indebted to Luciane Sarahyba and Nazareno dos Santos of the Molecular Biology Laboratory for their technical assistance.OBJECTIVES: Robust evidence now supports human papillomavirus (HPV) testing as a more effective option to screening and as more sensitive than cytology in detecting high-grade cervical intraepithelial neoplasia . Our goal was to analyze the performance of the Hybrid Capture II (HC2) assay for high-risk HPV (hrHPV) in women undergoing gynecological examination at a public health hospital as part of the evaluation of HPV screening as an alternative or complement to cytology. STUDY DESIGN: This analysis is a subset of a cross-sectional study carried out at a large public hospital serving a predominantly low-resource population. A total of 705 women were enrolled; the sensitivity and specificity of each test were estimated and compared. RESULTS: The analysis identified 272 hrHPV-positive women (mean age 36.3 years) and 433 hrHPV-negative women (mean age 41.2 years). HPV testing showed a significantly increased sensitivity of the HC2 assay versus cytology (84.5 vs. 69.7%; p < 0.0001) but a lower specificity (49.90 vs. 88.78%; p < 0.0001). CONCLUSION: The combination of both methods seems to be useful in improving detection of cervical lesions.Karger AGUniversidade do MinhoBeldi, Mariana CarmezimTacla, MaricyCaiaffa-Filho, HelioAb’Saber, AlexandreSiqueira, SheilaBaracat, Edmund ChadaAlves, Venâncio Avancini FerreiraLongatto Filho, Adhemar20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/23780eng0001-554710.1159/000335145www.karger.com/acyinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:45:53Zoai:repositorium.sdum.uminho.pt:1822/23780Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:43:48.091860Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Implementing human papillomavirus testing in a public health hospital : challenges and opportunities
title Implementing human papillomavirus testing in a public health hospital : challenges and opportunities
spellingShingle Implementing human papillomavirus testing in a public health hospital : challenges and opportunities
Beldi, Mariana Carmezim
Cytology
Pap test
Human papillomavirus testing
Primary screening
Science & Technology
title_short Implementing human papillomavirus testing in a public health hospital : challenges and opportunities
title_full Implementing human papillomavirus testing in a public health hospital : challenges and opportunities
title_fullStr Implementing human papillomavirus testing in a public health hospital : challenges and opportunities
title_full_unstemmed Implementing human papillomavirus testing in a public health hospital : challenges and opportunities
title_sort Implementing human papillomavirus testing in a public health hospital : challenges and opportunities
author Beldi, Mariana Carmezim
author_facet Beldi, Mariana Carmezim
Tacla, Maricy
Caiaffa-Filho, Helio
Ab’Saber, Alexandre
Siqueira, Sheila
Baracat, Edmund Chada
Alves, Venâncio Avancini Ferreira
Longatto Filho, Adhemar
author_role author
author2 Tacla, Maricy
Caiaffa-Filho, Helio
Ab’Saber, Alexandre
Siqueira, Sheila
Baracat, Edmund Chada
Alves, Venâncio Avancini Ferreira
Longatto Filho, Adhemar
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Beldi, Mariana Carmezim
Tacla, Maricy
Caiaffa-Filho, Helio
Ab’Saber, Alexandre
Siqueira, Sheila
Baracat, Edmund Chada
Alves, Venâncio Avancini Ferreira
Longatto Filho, Adhemar
dc.subject.por.fl_str_mv Cytology
Pap test
Human papillomavirus testing
Primary screening
Science & Technology
topic Cytology
Pap test
Human papillomavirus testing
Primary screening
Science & Technology
description Author's proof. The authors are indebted to Luciane Sarahyba and Nazareno dos Santos of the Molecular Biology Laboratory for their technical assistance.
publishDate 2012
dc.date.none.fl_str_mv 2012
2012-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/23780
url http://hdl.handle.net/1822/23780
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0001-5547
10.1159/000335145
www.karger.com/acy
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Karger AG
publisher.none.fl_str_mv Karger AG
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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