Reported Drug Allergy among Children Attending Day Care Centers

Detalhes bibliográficos
Autor(a) principal: Martins, Pedro
Data de Publicação: 2014
Outros Autores: Belo, Joana, Marques, João, Papoila, Ana Luísa, Caires, Iolanda, Araújo-Martins, José, Pedro, Catarina, Rosado-Pinto, José, Virella, Daniel, Leiria-Pinto, Paula, Neuparth, Nuno
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4789
Resumo: Introduction: Data about drug allergy prevalence in the general population, particularly in children, are lacking. This study aimed to estimate the prevalence of parent-reported drug allergy, in children attending day care centers in Lisbon and Oporto.Material and Methods: In Phase II of the “ENVIRH study – Environment and Health in Children Day Care Centers”, a health questionnaire which included questions about drug allergies was administered to children by stratified, random sampling of day care centers.Results: The final analysis included 1,169 questionnaires, 52.5% from boys. The mean age was 3.5 ± 1.5 years. The prevalence of reported drug allergy was 4.1% (95% CI: 3.0 - 5.2%). The most frequently reported drugs were antibiotics (27 cases) and NSAIDs (in 6 cases). In the multivariate analysis, reported drug allergy was directly associated with age (OR 1.19; 95% CI 1.01 - 1.41) and reported food allergy (OR 3.19; 95% CI 1.41 - 7.19). It was inversely associated with the level of parental education (OR 0.25; 95% CI 0.10 - 0.59).Discussion: Even though the limitations of the study our results are in accordance with those reported by previous authors and suggest that there is a high prevalence of reported drug allergy in the considered age group.Conclusion: A correct assessment of these situations is needed in order to avoid unnecessary drug evictions.Keywords: Child Day Care Centers; Child; Drug Hypersensitivity; Prevalence; Portugal.
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spelling Reported Drug Allergy among Children Attending Day Care CentersAlergia a Medicamentos Reportada em Crianças que Frequentam InfantáriosIntroduction: Data about drug allergy prevalence in the general population, particularly in children, are lacking. This study aimed to estimate the prevalence of parent-reported drug allergy, in children attending day care centers in Lisbon and Oporto.Material and Methods: In Phase II of the “ENVIRH study – Environment and Health in Children Day Care Centers”, a health questionnaire which included questions about drug allergies was administered to children by stratified, random sampling of day care centers.Results: The final analysis included 1,169 questionnaires, 52.5% from boys. The mean age was 3.5 ± 1.5 years. The prevalence of reported drug allergy was 4.1% (95% CI: 3.0 - 5.2%). The most frequently reported drugs were antibiotics (27 cases) and NSAIDs (in 6 cases). In the multivariate analysis, reported drug allergy was directly associated with age (OR 1.19; 95% CI 1.01 - 1.41) and reported food allergy (OR 3.19; 95% CI 1.41 - 7.19). It was inversely associated with the level of parental education (OR 0.25; 95% CI 0.10 - 0.59).Discussion: Even though the limitations of the study our results are in accordance with those reported by previous authors and suggest that there is a high prevalence of reported drug allergy in the considered age group.Conclusion: A correct assessment of these situations is needed in order to avoid unnecessary drug evictions.Keywords: Child Day Care Centers; Child; Drug Hypersensitivity; Prevalence; Portugal.Introdução: A prevalência de alergia a fármacos na população geral não se encontra devidamente caraterizada, existindo poucos estudos publicados que tenham abordado esta situação em crianças com idades inferior a seis anos de idade. Este estudo tem como objetivo principal estimar a prevalência de alergia a medicamentos reportada pelos pais de crianças de infantários de Lisboa e do Porto.Material e Métodos: No âmbito da Fase II do projeto “ENVIRH – Ambiente e Saúde em Creches e Infantários” foi aplicado um questionário sobre alergia a medicamentos aos pais das crianças, recrutadas por amostragem aleatória estratificada dos infantários.Resultados: Foram analisados 1 169 questionários, 52,5% de rapazes. A idade média foi de 3,5 ± 1,5 anos. A prevalência de alergia a medicamentos reportada foi de 4,1% (IC 95%: 3,0 - 5,2%). Os fármacos mais referidos foram os antibióticos (em 27 reações) e os AINEs (em seis reações). Na análise multivariável, a alergia a medicamentos reportada associou-se diretamente com a idade da criança (OR 1,19; IC 95% 1,01 - 1,41) e com a referência a alergia alimentar (OR 3,19; IC95% 1,41 - 7,19) e inversamente com o nível de escolaridade dos pais (OR 0,25; IC95% 0,10 - 0,59).Discussão: Apesar das limitações do estudo, os resultados encontram-se de acordo com o reportado por outros autores e sugerem que a prevalência reportada de alergia a medicamentos seja elevada no grupo etário estudado.Conclusão: Torna-se necessário que situações de alergia a medicamentos reportadas pelos pais sejam devidamente estudadas, no sentido de evitar evicções desnecessárias que possam condicionar opções terapêuticas em futuras situações de doença.Palavras-chave: Creches; Criança; Hipersensibilidade a Medicamentos; Prevalência; Portugal.Ordem dos Médicos2014-08-27info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4789oai:ojs.www.actamedicaportuguesa.com:article/4789Acta Médica Portuguesa; Vol. 27 No. 4 (2014): July-August; 444-449Acta Médica Portuguesa; Vol. 27 N.º 4 (2014): Julho-Agosto; 444-4491646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4789https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4789/4005https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4789/7327https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4789/7328Martins, PedroBelo, JoanaMarques, JoãoPapoila, Ana LuísaCaires, IolandaAraújo-Martins, JoséPedro, CatarinaRosado-Pinto, JoséVirella, DanielLeiria-Pinto, PaulaNeuparth, Nunoinfo:eu-repo/semantics/openAccess2022-12-20T11:04:00Zoai:ojs.www.actamedicaportuguesa.com:article/4789Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:58.580218Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Reported Drug Allergy among Children Attending Day Care Centers
Alergia a Medicamentos Reportada em Crianças que Frequentam Infantários
title Reported Drug Allergy among Children Attending Day Care Centers
spellingShingle Reported Drug Allergy among Children Attending Day Care Centers
Martins, Pedro
title_short Reported Drug Allergy among Children Attending Day Care Centers
title_full Reported Drug Allergy among Children Attending Day Care Centers
title_fullStr Reported Drug Allergy among Children Attending Day Care Centers
title_full_unstemmed Reported Drug Allergy among Children Attending Day Care Centers
title_sort Reported Drug Allergy among Children Attending Day Care Centers
author Martins, Pedro
author_facet Martins, Pedro
Belo, Joana
Marques, João
Papoila, Ana Luísa
Caires, Iolanda
Araújo-Martins, José
Pedro, Catarina
Rosado-Pinto, José
Virella, Daniel
Leiria-Pinto, Paula
Neuparth, Nuno
author_role author
author2 Belo, Joana
Marques, João
Papoila, Ana Luísa
Caires, Iolanda
Araújo-Martins, José
Pedro, Catarina
Rosado-Pinto, José
Virella, Daniel
Leiria-Pinto, Paula
Neuparth, Nuno
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Martins, Pedro
Belo, Joana
Marques, João
Papoila, Ana Luísa
Caires, Iolanda
Araújo-Martins, José
Pedro, Catarina
Rosado-Pinto, José
Virella, Daniel
Leiria-Pinto, Paula
Neuparth, Nuno
description Introduction: Data about drug allergy prevalence in the general population, particularly in children, are lacking. This study aimed to estimate the prevalence of parent-reported drug allergy, in children attending day care centers in Lisbon and Oporto.Material and Methods: In Phase II of the “ENVIRH study – Environment and Health in Children Day Care Centers”, a health questionnaire which included questions about drug allergies was administered to children by stratified, random sampling of day care centers.Results: The final analysis included 1,169 questionnaires, 52.5% from boys. The mean age was 3.5 ± 1.5 years. The prevalence of reported drug allergy was 4.1% (95% CI: 3.0 - 5.2%). The most frequently reported drugs were antibiotics (27 cases) and NSAIDs (in 6 cases). In the multivariate analysis, reported drug allergy was directly associated with age (OR 1.19; 95% CI 1.01 - 1.41) and reported food allergy (OR 3.19; 95% CI 1.41 - 7.19). It was inversely associated with the level of parental education (OR 0.25; 95% CI 0.10 - 0.59).Discussion: Even though the limitations of the study our results are in accordance with those reported by previous authors and suggest that there is a high prevalence of reported drug allergy in the considered age group.Conclusion: A correct assessment of these situations is needed in order to avoid unnecessary drug evictions.Keywords: Child Day Care Centers; Child; Drug Hypersensitivity; Prevalence; Portugal.
publishDate 2014
dc.date.none.fl_str_mv 2014-08-27
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 27 No. 4 (2014): July-August; 444-449
Acta Médica Portuguesa; Vol. 27 N.º 4 (2014): Julho-Agosto; 444-449
1646-0758
0870-399X
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