Unilateral progressive osseous heteroplasia

Detalhes bibliográficos
Autor(a) principal: Santiago, F
Data de Publicação: 2009
Outros Autores: Veira, R, Cordeiro, M, Tellechea, O, Figueiredo, A
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.4/1115
Resumo: A 50-year-old male patient presented with firm subcutaneous nodules and plaques with a gritty texture, unilaterally affecting the left side of the trunk and the left limbs. These lesions had had a progressive course since early childhood and caused functional impairment. There was no family history of similar disorders. No phospho-calcium metabolism abnormalities were observed. Biopsies of the affected areas demonstrated osteoma cutis. Analysis of DNA showed no mutation of the GNAS gene. The clinical features were consistent with progressive osseous heteroplasia, atypically presented in a unilateral form, probably revealing a mosaic distribution.
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spelling Unilateral progressive osseous heteroplasiaOssificação HeterotópicaDoenças da PeleA 50-year-old male patient presented with firm subcutaneous nodules and plaques with a gritty texture, unilaterally affecting the left side of the trunk and the left limbs. These lesions had had a progressive course since early childhood and caused functional impairment. There was no family history of similar disorders. No phospho-calcium metabolism abnormalities were observed. Biopsies of the affected areas demonstrated osteoma cutis. Analysis of DNA showed no mutation of the GNAS gene. The clinical features were consistent with progressive osseous heteroplasia, atypically presented in a unilateral form, probably revealing a mosaic distribution.RIHUCSantiago, FVeira, RCordeiro, MTellechea, OFigueiredo, A2011-11-08T12:54:21Z20092009-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.4/1115engEur J Dermatol. 2009 May-Jun;19(3):214-5.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-11T14:22:20Zoai:rihuc.huc.min-saude.pt:10400.4/1115Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:03:40.286778Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Unilateral progressive osseous heteroplasia
title Unilateral progressive osseous heteroplasia
spellingShingle Unilateral progressive osseous heteroplasia
Santiago, F
Ossificação Heterotópica
Doenças da Pele
title_short Unilateral progressive osseous heteroplasia
title_full Unilateral progressive osseous heteroplasia
title_fullStr Unilateral progressive osseous heteroplasia
title_full_unstemmed Unilateral progressive osseous heteroplasia
title_sort Unilateral progressive osseous heteroplasia
author Santiago, F
author_facet Santiago, F
Veira, R
Cordeiro, M
Tellechea, O
Figueiredo, A
author_role author
author2 Veira, R
Cordeiro, M
Tellechea, O
Figueiredo, A
author2_role author
author
author
author
dc.contributor.none.fl_str_mv RIHUC
dc.contributor.author.fl_str_mv Santiago, F
Veira, R
Cordeiro, M
Tellechea, O
Figueiredo, A
dc.subject.por.fl_str_mv Ossificação Heterotópica
Doenças da Pele
topic Ossificação Heterotópica
Doenças da Pele
description A 50-year-old male patient presented with firm subcutaneous nodules and plaques with a gritty texture, unilaterally affecting the left side of the trunk and the left limbs. These lesions had had a progressive course since early childhood and caused functional impairment. There was no family history of similar disorders. No phospho-calcium metabolism abnormalities were observed. Biopsies of the affected areas demonstrated osteoma cutis. Analysis of DNA showed no mutation of the GNAS gene. The clinical features were consistent with progressive osseous heteroplasia, atypically presented in a unilateral form, probably revealing a mosaic distribution.
publishDate 2009
dc.date.none.fl_str_mv 2009
2009-01-01T00:00:00Z
2011-11-08T12:54:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.4/1115
url http://hdl.handle.net/10400.4/1115
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Eur J Dermatol. 2009 May-Jun;19(3):214-5.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron:RCAAP
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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