Plasmablastic lymphoma: an atypical cutaneous presentation of a rare entity

• Autor(a) principal: Mota, F.
• Data de Publicação: 2016
• Outros Autores: Mesquita, B., Carvalho, S., Coelho, A., Velho, G., Lima, M., Selores, M.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10400.16/2109
• topic: plasmablastic lymphoma; B-cell lymphomas; Human herpesvirus 8; HIV infection

Plasmablastic lymphoma is a very rare B-cell lymphoma typically associated with immunosuppression: It occurs primarily in the oral cavity, although some cases were reported in other organs and tissues.To date, only 10 cases of primary cutaneous plasmablastic lymphoma have been described. Clinically, primary cutaneous plasmablastic lymphoma presents as non-specific cutaneous lesions (purple nodules, erythematous infiltrated plaques). In previously described cases, as in this case, histology and immunohistochemistry are required to make the diagnosis. Owing to the rarity of this entity, there is no established therapy, which makes its management an individualized, patient-based decision.