A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/50302 |
Resumo: | Introduction: The majority of parvovirus B19 infections are asymptomatic. In childhood, however, they may present as the fifth disease and in adults their manifestations can vary from mild, non-specific, cold-like symptoms to other forms of presentations. Papular-purpuric gloves and socks syndrome (PPGSS) is an uncommon form of parvovirus B19 infection, characterized by symmetric, pruriginous and painful erythema and edema of feet and hands. Generally, systemic symptoms are usually mild and dissemination to other body regions occurs in only 50% of the cases. The rash gradually progresses to petechiae and purpura delineating well demarcated "socks" and "gloves" on both feet and hands. The diagnosis is predominantly based on the clinical features. Serologic conversion is not considered as evidence of parvovirus B19 infection and histopathological findings from lesional skin are not specific. There are no definite antiviral drugs or vaccines against parvovirus. Patients with PPGSS require only symptomatic therapy. Case Report: We report the case of a 30-year-old female with this characteristic erythema caused by the parvovirus B19. Nevertheless, this case is remarkable because the patient had significant systemic manifestations and an exuberant perineal and oropharyngeal involvement. Further, the erythema assumed a bullous expression that has not been so commonly reported. A biopsy was performed which was unspecific and the diagnosis was confirmed with the serology and molecular detection of the virus in blood sample as well as on mouth swab. Our patient needed treatment to control pain and pruritus, fever was self-limited. Conclusion: A high index of suspicion is essential to diagnose patients with this syndrome. Early recognition can prevent unproductive measures and the good management of this infection. |
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A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19Human parvovirus b19Papular-purpuric socks and gloves syndromeViral infectionParvovirus b19 infectionCiências Médicas::Medicina BásicaIntroduction: The majority of parvovirus B19 infections are asymptomatic. In childhood, however, they may present as the fifth disease and in adults their manifestations can vary from mild, non-specific, cold-like symptoms to other forms of presentations. Papular-purpuric gloves and socks syndrome (PPGSS) is an uncommon form of parvovirus B19 infection, characterized by symmetric, pruriginous and painful erythema and edema of feet and hands. Generally, systemic symptoms are usually mild and dissemination to other body regions occurs in only 50% of the cases. The rash gradually progresses to petechiae and purpura delineating well demarcated "socks" and "gloves" on both feet and hands. The diagnosis is predominantly based on the clinical features. Serologic conversion is not considered as evidence of parvovirus B19 infection and histopathological findings from lesional skin are not specific. There are no definite antiviral drugs or vaccines against parvovirus. Patients with PPGSS require only symptomatic therapy. Case Report: We report the case of a 30-year-old female with this characteristic erythema caused by the parvovirus B19. Nevertheless, this case is remarkable because the patient had significant systemic manifestations and an exuberant perineal and oropharyngeal involvement. Further, the erythema assumed a bullous expression that has not been so commonly reported. A biopsy was performed which was unspecific and the diagnosis was confirmed with the serology and molecular detection of the virus in blood sample as well as on mouth swab. Our patient needed treatment to control pain and pruritus, fever was self-limited. Conclusion: A high index of suspicion is essential to diagnose patients with this syndrome. Early recognition can prevent unproductive measures and the good management of this infection.info:eu-repo/semantics/publishedVersionEdorium JournalsUniversidade do MinhoBurmester,InêsJoão, André Santa CruzRamalho, JulietaRegadas, Maria JoãoGouveia, PauloGomes, Guilherme CastroÂngela, CristinaOliveira, NarcisoMota-Garcia, FernandoSilva, António Oliveira e2016-01-152016-01-15T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/50302engBurmester, I., Santa-Cruz, A., Ramalho, J., et. al. (2016). A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19. International Journal of Case Reports and Images (IJCRI), 7(3), 143-1480976-319810.5348/ijcri-201622-CR-10609http://www.ijcasereportsandimages.com/archive/2016/003-2016-ijcri/CR-10609-03-2016-burmester/ijcri-1060903201609-burmester-full-text.phpinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:21:19Zoai:repositorium.sdum.uminho.pt:1822/50302Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:14:33.694670Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19 |
title |
A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19 |
spellingShingle |
A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19 Burmester,Inês Human parvovirus b19 Papular-purpuric socks and gloves syndrome Viral infection Parvovirus b19 infection Ciências Médicas::Medicina Básica |
title_short |
A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19 |
title_full |
A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19 |
title_fullStr |
A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19 |
title_full_unstemmed |
A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19 |
title_sort |
A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19 |
author |
Burmester,Inês |
author_facet |
Burmester,Inês João, André Santa Cruz Ramalho, Julieta Regadas, Maria João Gouveia, Paulo Gomes, Guilherme Castro Ângela, Cristina Oliveira, Narciso Mota-Garcia, Fernando Silva, António Oliveira e |
author_role |
author |
author2 |
João, André Santa Cruz Ramalho, Julieta Regadas, Maria João Gouveia, Paulo Gomes, Guilherme Castro Ângela, Cristina Oliveira, Narciso Mota-Garcia, Fernando Silva, António Oliveira e |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Burmester,Inês João, André Santa Cruz Ramalho, Julieta Regadas, Maria João Gouveia, Paulo Gomes, Guilherme Castro Ângela, Cristina Oliveira, Narciso Mota-Garcia, Fernando Silva, António Oliveira e |
dc.subject.por.fl_str_mv |
Human parvovirus b19 Papular-purpuric socks and gloves syndrome Viral infection Parvovirus b19 infection Ciências Médicas::Medicina Básica |
topic |
Human parvovirus b19 Papular-purpuric socks and gloves syndrome Viral infection Parvovirus b19 infection Ciências Médicas::Medicina Básica |
description |
Introduction: The majority of parvovirus B19 infections are asymptomatic. In childhood, however, they may present as the fifth disease and in adults their manifestations can vary from mild, non-specific, cold-like symptoms to other forms of presentations. Papular-purpuric gloves and socks syndrome (PPGSS) is an uncommon form of parvovirus B19 infection, characterized by symmetric, pruriginous and painful erythema and edema of feet and hands. Generally, systemic symptoms are usually mild and dissemination to other body regions occurs in only 50% of the cases. The rash gradually progresses to petechiae and purpura delineating well demarcated "socks" and "gloves" on both feet and hands. The diagnosis is predominantly based on the clinical features. Serologic conversion is not considered as evidence of parvovirus B19 infection and histopathological findings from lesional skin are not specific. There are no definite antiviral drugs or vaccines against parvovirus. Patients with PPGSS require only symptomatic therapy. Case Report: We report the case of a 30-year-old female with this characteristic erythema caused by the parvovirus B19. Nevertheless, this case is remarkable because the patient had significant systemic manifestations and an exuberant perineal and oropharyngeal involvement. Further, the erythema assumed a bullous expression that has not been so commonly reported. A biopsy was performed which was unspecific and the diagnosis was confirmed with the serology and molecular detection of the virus in blood sample as well as on mouth swab. Our patient needed treatment to control pain and pruritus, fever was self-limited. Conclusion: A high index of suspicion is essential to diagnose patients with this syndrome. Early recognition can prevent unproductive measures and the good management of this infection. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-01-15 2016-01-15T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/50302 |
url |
http://hdl.handle.net/1822/50302 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Burmester, I., Santa-Cruz, A., Ramalho, J., et. al. (2016). A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19. International Journal of Case Reports and Images (IJCRI), 7(3), 143-148 0976-3198 10.5348/ijcri-201622-CR-10609 http://www.ijcasereportsandimages.com/archive/2016/003-2016-ijcri/CR-10609-03-2016-burmester/ijcri-1060903201609-burmester-full-text.php |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Edorium Journals |
publisher.none.fl_str_mv |
Edorium Journals |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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