Quantum Biochemistry Screening and In Vitro Evaluation of Leishmania Metalloproteinase Inhibitors

• Autor(a) principal: Moreno, Cláudia Jassica Gonçalves
• Data de Publicação: 2022
• Outros Autores: Farias, Henriqueta Monalisa, de Lima Medeiros, Rafael, de Brito Pinto, Talita Katiane, de Freitas Oliveira, Johny Wysllas, de Sousa, Francimar Lopes, de Medeiros, Mayara Jane Campos, Amorim-Carmo, Bruno, Santos-Gomes, Gabriela, de Lima Pontes, Daniel, Rocha, Hugo Alexandre Oliveira, Frazão, Nilton Fereira, Silva, Marcelo Sousa
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10362/145140
• topic: Leishmaniaspp; leishmanolysin; metalloprotease inhibitors; MFCC (Molecular Fractionation with Conjugate Caps); Catalysis; Molecular Biology; Spectroscopy; Computer Science Applications; Physical and Theoretical Chemistry; SDG 3 - Good Health and Well-being; SDG 1 - No Poverty; SDG 10 - Reduced Inequalities

Special Issue Molecular Research on Vector-Borne Diseases of Medical Interest: From Bench to Application 2.0 Funding Information: Global Health and Tropical Medicine funded this research: Grant number IHMT-UID/multi/04413/2013 and Grant number PTDC/CVT-CVT/28908/2017, FCT-Portugal. Funding Information: We would like to thank to CNPq/Brazil, CAPES/Brazil and FCT/Portugal for grants and fellowships. C.J.G.M., J.W.d.F.O., T.K.d.B.P., F.L.d.S.J. and B.A.-C. thank the financial support (PhD and Post-doctoral fellowships) provided by Capes/Brazil. M.S.S. and H.A.O.R. thank CNPq/Brazil for the Research Grant (Bolsa de Produtividade em Pesquisa). We also would like to thank the Department of Materials Engineering at UFRN for allowing the use of their scanning electron microscope, and the Department of Biochemistry at UFRN for allowing the use of their flow cytometer. Publisher Copyright: © 2022 by the authors.