Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.1/18881 |
Resumo: | Cinnamon from the bark of Cinnamomum species is one of the most important spices used worldwide in food and as a traditional medicine for centuries. It has substantial benefits for human health including its protective role on cardiovascular diseases. This review provides an overview of the cardiovascular protective effects of cinna-mon and its major bioactive constituents. Reviewed literature showed sufficient evidence that cinnamon can reduce the risk of cardiovascular diseases, including cardiac ischemia, cardiac hypertrophy, and myocardial infarction. Furthermore, cinnamon exhibited beneficial effects on cardiovascular-related comorbidities like diabetes, and other metabolic disorders, and showed antioxidant and anti-inflammatory effects. Cinnamon contains several bioactive compounds such as phenolics and volatile compounds. Cinnamaldehyde and cinnamic acid are among the main cinnamon compounds with protective effects on cardiovascular diseases through different molecular mechanisms. Although the protective effects of cinnamon and its main compounds have been extensively reported, more preclinical and clinical studies are still required before its use as a biopharmaceutical agent. |
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Cardiovascular protective effect of cinnamon and its major bioactive constituents: An updateCinnamaldehydeCinnamonCardiovascular effectsLauraceaeClinical studiesCinnamon from the bark of Cinnamomum species is one of the most important spices used worldwide in food and as a traditional medicine for centuries. It has substantial benefits for human health including its protective role on cardiovascular diseases. This review provides an overview of the cardiovascular protective effects of cinna-mon and its major bioactive constituents. Reviewed literature showed sufficient evidence that cinnamon can reduce the risk of cardiovascular diseases, including cardiac ischemia, cardiac hypertrophy, and myocardial infarction. Furthermore, cinnamon exhibited beneficial effects on cardiovascular-related comorbidities like diabetes, and other metabolic disorders, and showed antioxidant and anti-inflammatory effects. Cinnamon contains several bioactive compounds such as phenolics and volatile compounds. Cinnamaldehyde and cinnamic acid are among the main cinnamon compounds with protective effects on cardiovascular diseases through different molecular mechanisms. Although the protective effects of cinnamon and its main compounds have been extensively reported, more preclinical and clinical studies are still required before its use as a biopharmaceutical agent.2020R1G1A1004667ElsevierSapientiaDas, GitishreeGonçalves, SandraBasilio Heredia, J.Romano, AnabelaJiménez-Ortega, Luis AlfonsoGutiérrez-Grijalva, Erick P.Shin, Han SeungPatra, Jayanta Kumar2023-01-20T15:18:21Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/18881eng10.1016/j.jff.2022.1050452214-9414info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:31:13Zoai:sapientia.ualg.pt:10400.1/18881Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:08:34.316495Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update |
title |
Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update |
spellingShingle |
Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update Das, Gitishree Cinnamaldehyde Cinnamon Cardiovascular effects Lauraceae Clinical studies |
title_short |
Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update |
title_full |
Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update |
title_fullStr |
Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update |
title_full_unstemmed |
Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update |
title_sort |
Cardiovascular protective effect of cinnamon and its major bioactive constituents: An update |
author |
Das, Gitishree |
author_facet |
Das, Gitishree Gonçalves, Sandra Basilio Heredia, J. Romano, Anabela Jiménez-Ortega, Luis Alfonso Gutiérrez-Grijalva, Erick P. Shin, Han Seung Patra, Jayanta Kumar |
author_role |
author |
author2 |
Gonçalves, Sandra Basilio Heredia, J. Romano, Anabela Jiménez-Ortega, Luis Alfonso Gutiérrez-Grijalva, Erick P. Shin, Han Seung Patra, Jayanta Kumar |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Sapientia |
dc.contributor.author.fl_str_mv |
Das, Gitishree Gonçalves, Sandra Basilio Heredia, J. Romano, Anabela Jiménez-Ortega, Luis Alfonso Gutiérrez-Grijalva, Erick P. Shin, Han Seung Patra, Jayanta Kumar |
dc.subject.por.fl_str_mv |
Cinnamaldehyde Cinnamon Cardiovascular effects Lauraceae Clinical studies |
topic |
Cinnamaldehyde Cinnamon Cardiovascular effects Lauraceae Clinical studies |
description |
Cinnamon from the bark of Cinnamomum species is one of the most important spices used worldwide in food and as a traditional medicine for centuries. It has substantial benefits for human health including its protective role on cardiovascular diseases. This review provides an overview of the cardiovascular protective effects of cinna-mon and its major bioactive constituents. Reviewed literature showed sufficient evidence that cinnamon can reduce the risk of cardiovascular diseases, including cardiac ischemia, cardiac hypertrophy, and myocardial infarction. Furthermore, cinnamon exhibited beneficial effects on cardiovascular-related comorbidities like diabetes, and other metabolic disorders, and showed antioxidant and anti-inflammatory effects. Cinnamon contains several bioactive compounds such as phenolics and volatile compounds. Cinnamaldehyde and cinnamic acid are among the main cinnamon compounds with protective effects on cardiovascular diseases through different molecular mechanisms. Although the protective effects of cinnamon and its main compounds have been extensively reported, more preclinical and clinical studies are still required before its use as a biopharmaceutical agent. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022 2022-01-01T00:00:00Z 2023-01-20T15:18:21Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.1/18881 |
url |
http://hdl.handle.net/10400.1/18881 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.jff.2022.105045 2214-9414 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133332338900992 |