Rickettsial Infection Caused by Accidental Conjunctival Inoculation

Detalhes bibliográficos
Autor(a) principal: Brissos, J
Data de Publicação: 2015
Outros Autores: de Sousa, R, Santos, AS, Gouveia, C
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/2392
Resumo: The most common transmission route of tick-borne Rickettsia is through tick bite; nevertheless, other transmission routes should also be considered. We report a case of rickettsial infection in a 15-year-old boy caused by accidental contamination of the conjunctiva through the infected fluid of a crushed engorged tick removed from a dog. Right eye pain, conjunctival hyperaemia with mucopurulent exudate, chemosis and eyelid oedema were the first signs and symptoms. Two days later, the boy developed fever, myalgia, headache, abdominal pain and was vomiting; physical examination showed multiple cervical adenopathies but no rash. He was treated with doxycycline (200 mg/day) for 7 days with progressive resolution of clinical signs. Rickettsial infection was confirmed by immunofluorescence assay with serological seroconversion in two consecutive samples. Rickettsia conorii or Rickettsia massiliae were the possible causal agents since they are the Rickettsia spp found in the Rhipicephalus sanguineus dog tick in Portugal.
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spelling Rickettsial Infection Caused by Accidental Conjunctival InoculationAccidentsAnimal HusbandryAnti-Bacterial Agents/therapeutic useBoutonneuse Fever/drug therapyBoutonneuse Fever/etiologyConjunctivitis, Bacterial/drug therapyDoxycycline/therapeutic useRickettsiaAnimalsAdolescentHDE PEDThe most common transmission route of tick-borne Rickettsia is through tick bite; nevertheless, other transmission routes should also be considered. We report a case of rickettsial infection in a 15-year-old boy caused by accidental contamination of the conjunctiva through the infected fluid of a crushed engorged tick removed from a dog. Right eye pain, conjunctival hyperaemia with mucopurulent exudate, chemosis and eyelid oedema were the first signs and symptoms. Two days later, the boy developed fever, myalgia, headache, abdominal pain and was vomiting; physical examination showed multiple cervical adenopathies but no rash. He was treated with doxycycline (200 mg/day) for 7 days with progressive resolution of clinical signs. Rickettsial infection was confirmed by immunofluorescence assay with serological seroconversion in two consecutive samples. Rickettsia conorii or Rickettsia massiliae were the possible causal agents since they are the Rickettsia spp found in the Rhipicephalus sanguineus dog tick in Portugal.BMJ Publishing GroupRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEBrissos, Jde Sousa, RSantos, ASGouveia, C2016-02-18T12:42:47Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2392engBMJ Case Rep 201510.1136/bcr-2014-207029info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:36:45Zoai:repositorio.chlc.min-saude.pt:10400.17/2392Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:19:44.917678Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Rickettsial Infection Caused by Accidental Conjunctival Inoculation
title Rickettsial Infection Caused by Accidental Conjunctival Inoculation
spellingShingle Rickettsial Infection Caused by Accidental Conjunctival Inoculation
Brissos, J
Accidents
Animal Husbandry
Anti-Bacterial Agents/therapeutic use
Boutonneuse Fever/drug therapy
Boutonneuse Fever/etiology
Conjunctivitis, Bacterial/drug therapy
Doxycycline/therapeutic use
Rickettsia
Animals
Adolescent
HDE PED
title_short Rickettsial Infection Caused by Accidental Conjunctival Inoculation
title_full Rickettsial Infection Caused by Accidental Conjunctival Inoculation
title_fullStr Rickettsial Infection Caused by Accidental Conjunctival Inoculation
title_full_unstemmed Rickettsial Infection Caused by Accidental Conjunctival Inoculation
title_sort Rickettsial Infection Caused by Accidental Conjunctival Inoculation
author Brissos, J
author_facet Brissos, J
de Sousa, R
Santos, AS
Gouveia, C
author_role author
author2 de Sousa, R
Santos, AS
Gouveia, C
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Brissos, J
de Sousa, R
Santos, AS
Gouveia, C
dc.subject.por.fl_str_mv Accidents
Animal Husbandry
Anti-Bacterial Agents/therapeutic use
Boutonneuse Fever/drug therapy
Boutonneuse Fever/etiology
Conjunctivitis, Bacterial/drug therapy
Doxycycline/therapeutic use
Rickettsia
Animals
Adolescent
HDE PED
topic Accidents
Animal Husbandry
Anti-Bacterial Agents/therapeutic use
Boutonneuse Fever/drug therapy
Boutonneuse Fever/etiology
Conjunctivitis, Bacterial/drug therapy
Doxycycline/therapeutic use
Rickettsia
Animals
Adolescent
HDE PED
description The most common transmission route of tick-borne Rickettsia is through tick bite; nevertheless, other transmission routes should also be considered. We report a case of rickettsial infection in a 15-year-old boy caused by accidental contamination of the conjunctiva through the infected fluid of a crushed engorged tick removed from a dog. Right eye pain, conjunctival hyperaemia with mucopurulent exudate, chemosis and eyelid oedema were the first signs and symptoms. Two days later, the boy developed fever, myalgia, headache, abdominal pain and was vomiting; physical examination showed multiple cervical adenopathies but no rash. He was treated with doxycycline (200 mg/day) for 7 days with progressive resolution of clinical signs. Rickettsial infection was confirmed by immunofluorescence assay with serological seroconversion in two consecutive samples. Rickettsia conorii or Rickettsia massiliae were the possible causal agents since they are the Rickettsia spp found in the Rhipicephalus sanguineus dog tick in Portugal.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2016-02-18T12:42:47Z
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dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv BMJ Case Rep 2015
10.1136/bcr-2014-207029
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publisher.none.fl_str_mv BMJ Publishing Group
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