Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regeneration

Detalhes bibliográficos
Autor(a) principal: Yan, Leping
Data de Publicação: 2012
Outros Autores: Oliveira, Joaquim M., Oliveira, A. L., Reis, R. L.
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/23148
Resumo: Objectives: Osteochondral defect is a common condtion in clinic. Satisfactory outcomes are rarely achieved by traditional methods. Tissue engineering might be a promising strategy for this hinder. The aim of this study is to mimick the stratified structure of osteochondral tissue, by developing a bilayered scaffold for osteochondral regeneration. The developed bilayered scaffold is composed of a porous silk fibroin scaffold as the cartilage-like layer and a porous silk fibroin/nano-calcium phosphate (CaP) scaffold as the bone-like layer.
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spelling Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regenerationBilayered scaffoldsSilk fibroinScience & TechnologyObjectives: Osteochondral defect is a common condtion in clinic. Satisfactory outcomes are rarely achieved by traditional methods. Tissue engineering might be a promising strategy for this hinder. The aim of this study is to mimick the stratified structure of osteochondral tissue, by developing a bilayered scaffold for osteochondral regeneration. The developed bilayered scaffold is composed of a porous silk fibroin scaffold as the cartilage-like layer and a porous silk fibroin/nano-calcium phosphate (CaP) scaffold as the bone-like layer.John Wiley and SonsUniversidade do MinhoYan, LepingOliveira, Joaquim M.Oliveira, A. L.Reis, R. L.2012-102012-10-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/1822/23148eng1932-6254info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-11T07:26:02Zoai:repositorium.sdum.uminho.pt:1822/23148Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-11T07:26:02Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regeneration
title Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regeneration
spellingShingle Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regeneration
Yan, Leping
Bilayered scaffolds
Silk fibroin
Science & Technology
title_short Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regeneration
title_full Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regeneration
title_fullStr Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regeneration
title_full_unstemmed Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regeneration
title_sort Development of a bilayered scaffold based on silk fibroin and silk fibroin/nano-calcium phosphate for osteochondral regeneration
author Yan, Leping
author_facet Yan, Leping
Oliveira, Joaquim M.
Oliveira, A. L.
Reis, R. L.
author_role author
author2 Oliveira, Joaquim M.
Oliveira, A. L.
Reis, R. L.
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Yan, Leping
Oliveira, Joaquim M.
Oliveira, A. L.
Reis, R. L.
dc.subject.por.fl_str_mv Bilayered scaffolds
Silk fibroin
Science & Technology
topic Bilayered scaffolds
Silk fibroin
Science & Technology
description Objectives: Osteochondral defect is a common condtion in clinic. Satisfactory outcomes are rarely achieved by traditional methods. Tissue engineering might be a promising strategy for this hinder. The aim of this study is to mimick the stratified structure of osteochondral tissue, by developing a bilayered scaffold for osteochondral regeneration. The developed bilayered scaffold is composed of a porous silk fibroin scaffold as the cartilage-like layer and a porous silk fibroin/nano-calcium phosphate (CaP) scaffold as the bone-like layer.
publishDate 2012
dc.date.none.fl_str_mv 2012-10
2012-10-01T00:00:00Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/23148
url http://hdl.handle.net/1822/23148
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1932-6254
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv John Wiley and Sons
publisher.none.fl_str_mv John Wiley and Sons
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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