Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.16/2948 |
Resumo: | The majority of acute iron toxicity cases occur in young children from accidental ingestion. In adults, iron poisoning is rare and mostly due to intentional ingestion. Physicians, particularly those who do not routinely treat pediatric patients, are often unfamiliar with the clinical manifestation of iron poisoning, its management, and its potential for multiple organ failure, especially liver damage. Severe acute hepatotoxicity treated with liver transplantation is rare in adults, with very limited published literature. We report a case of a severe iron tablet overdose with suicidal intent that progressed to fulminant hepatic failure despite medical treatment, ultimately treated with liver transplantation. |
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Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdoseacute liver failurehepatotoxicityiron intoxicationliver transplantsuicide attemptThe majority of acute iron toxicity cases occur in young children from accidental ingestion. In adults, iron poisoning is rare and mostly due to intentional ingestion. Physicians, particularly those who do not routinely treat pediatric patients, are often unfamiliar with the clinical manifestation of iron poisoning, its management, and its potential for multiple organ failure, especially liver damage. Severe acute hepatotoxicity treated with liver transplantation is rare in adults, with very limited published literature. We report a case of a severe iron tablet overdose with suicidal intent that progressed to fulminant hepatic failure despite medical treatment, ultimately treated with liver transplantation.Cureus, Inc.Repositório Científico da Unidade Local de Saúde de Santo AntónioEça, RosárioFerreira, SofiaGandara, JuditPessegueiro Miranda, HelenaDaniel, Jorge2024-06-18T09:25:30Z2023-112023-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.16/2948eng2168-818410.7759/cureus.48392info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-11-21T04:56:46Zoai:repositorio.chporto.pt:10400.16/2948Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-11-21T04:56:46Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose |
title |
Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose |
spellingShingle |
Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose Eça, Rosário acute liver failure hepatotoxicity iron intoxication liver transplant suicide attempt |
title_short |
Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose |
title_full |
Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose |
title_fullStr |
Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose |
title_full_unstemmed |
Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose |
title_sort |
Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose |
author |
Eça, Rosário |
author_facet |
Eça, Rosário Ferreira, Sofia Gandara, Judit Pessegueiro Miranda, Helena Daniel, Jorge |
author_role |
author |
author2 |
Ferreira, Sofia Gandara, Judit Pessegueiro Miranda, Helena Daniel, Jorge |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico da Unidade Local de Saúde de Santo António |
dc.contributor.author.fl_str_mv |
Eça, Rosário Ferreira, Sofia Gandara, Judit Pessegueiro Miranda, Helena Daniel, Jorge |
dc.subject.por.fl_str_mv |
acute liver failure hepatotoxicity iron intoxication liver transplant suicide attempt |
topic |
acute liver failure hepatotoxicity iron intoxication liver transplant suicide attempt |
description |
The majority of acute iron toxicity cases occur in young children from accidental ingestion. In adults, iron poisoning is rare and mostly due to intentional ingestion. Physicians, particularly those who do not routinely treat pediatric patients, are often unfamiliar with the clinical manifestation of iron poisoning, its management, and its potential for multiple organ failure, especially liver damage. Severe acute hepatotoxicity treated with liver transplantation is rare in adults, with very limited published literature. We report a case of a severe iron tablet overdose with suicidal intent that progressed to fulminant hepatic failure despite medical treatment, ultimately treated with liver transplantation. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-11 2023-11-01T00:00:00Z 2024-06-18T09:25:30Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.16/2948 |
url |
http://hdl.handle.net/10400.16/2948 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2168-8184 10.7759/cureus.48392 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Cureus, Inc. |
publisher.none.fl_str_mv |
Cureus, Inc. |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
_version_ |
1817549549974061056 |