Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction.
Autor(a) principal: | |
---|---|
Data de Publicação: | 1980 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4294 |
Resumo: | Using Holter recordings and based on the principle that most of the survivors of acute myocardial infarction who are going to die suddenly after hospital discharge are those who present ventricular premature beats (VPB), the authors have studied the effect of three different antidysrhythmic drugs - procainamide (PA), oxprenolol (OX) and amiodarones. (AMIOD) - in late phase of acute myocardial infarction. All the trials have been controlled Procainamide (47 patients studied), in comparison with placebo (PL), revealed to be effective (a) in supressing and diminishing VPB/hour (p=0.0425), and (b) in maintaining patients with no VPB (PA 89.6% - PL 64.7%). Oxprenolol (27 patients studied), in comparison with placebo, revealed to be effective (a) in maintaining patients with no VPB (p=0.0525), and (b) in avoiding the increase of VPB/hour (p=0.0576). Finally amiodarone (37 patients studied), in comparison with placebo, was effective (a) in maintaining patients with no VPB (AMIOD 50% - PL 39%), (b) in diminishing VPB/hour (AMIOD 29% - PL 9%), and (c) in avoiding the increase of VPB/hour (AMIOD 79% - PL 48%). The authors finish their paper emphasizing that no antidysrhythmic drug should be introduced in clinical practice before being submitted to controlled studies with Holter electrocardiography. |
id |
RCAP_0ff27eadca7c5dd98b066474c3f0ce68 |
---|---|
oai_identifier_str |
oai:ojs.www.actamedicaportuguesa.com:article/4294 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction.Using Holter recordings and based on the principle that most of the survivors of acute myocardial infarction who are going to die suddenly after hospital discharge are those who present ventricular premature beats (VPB), the authors have studied the effect of three different antidysrhythmic drugs - procainamide (PA), oxprenolol (OX) and amiodarones. (AMIOD) - in late phase of acute myocardial infarction. All the trials have been controlled Procainamide (47 patients studied), in comparison with placebo (PL), revealed to be effective (a) in supressing and diminishing VPB/hour (p=0.0425), and (b) in maintaining patients with no VPB (PA 89.6% - PL 64.7%). Oxprenolol (27 patients studied), in comparison with placebo, revealed to be effective (a) in maintaining patients with no VPB (p=0.0525), and (b) in avoiding the increase of VPB/hour (p=0.0576). Finally amiodarone (37 patients studied), in comparison with placebo, was effective (a) in maintaining patients with no VPB (AMIOD 50% - PL 39%), (b) in diminishing VPB/hour (AMIOD 29% - PL 9%), and (c) in avoiding the increase of VPB/hour (AMIOD 79% - PL 48%). The authors finish their paper emphasizing that no antidysrhythmic drug should be introduced in clinical practice before being submitted to controlled studies with Holter electrocardiography.Ordem dos Médicos1980-12-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4294oai:ojs.www.actamedicaportuguesa.com:article/4294Acta Médica Portuguesa; Vol. 2 (1980): Suplemento; 27-32Acta Médica Portuguesa; Vol. 2 (1980): Suplemento; 27-321646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4294https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4294/3384Tuna, J. L.Correia, M. J.d'Almeida, V. CorrêaMourão, L.da Costa, F. LealRibeiro, C.info:eu-repo/semantics/openAccess2022-12-20T11:03:34Zoai:ojs.www.actamedicaportuguesa.com:article/4294Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:49.865670Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction. |
title |
Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction. |
spellingShingle |
Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction. Tuna, J. L. |
title_short |
Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction. |
title_full |
Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction. |
title_fullStr |
Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction. |
title_full_unstemmed |
Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction. |
title_sort |
Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction. |
author |
Tuna, J. L. |
author_facet |
Tuna, J. L. Correia, M. J. d'Almeida, V. Corrêa Mourão, L. da Costa, F. Leal Ribeiro, C. |
author_role |
author |
author2 |
Correia, M. J. d'Almeida, V. Corrêa Mourão, L. da Costa, F. Leal Ribeiro, C. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Tuna, J. L. Correia, M. J. d'Almeida, V. Corrêa Mourão, L. da Costa, F. Leal Ribeiro, C. |
description |
Using Holter recordings and based on the principle that most of the survivors of acute myocardial infarction who are going to die suddenly after hospital discharge are those who present ventricular premature beats (VPB), the authors have studied the effect of three different antidysrhythmic drugs - procainamide (PA), oxprenolol (OX) and amiodarones. (AMIOD) - in late phase of acute myocardial infarction. All the trials have been controlled Procainamide (47 patients studied), in comparison with placebo (PL), revealed to be effective (a) in supressing and diminishing VPB/hour (p=0.0425), and (b) in maintaining patients with no VPB (PA 89.6% - PL 64.7%). Oxprenolol (27 patients studied), in comparison with placebo, revealed to be effective (a) in maintaining patients with no VPB (p=0.0525), and (b) in avoiding the increase of VPB/hour (p=0.0576). Finally amiodarone (37 patients studied), in comparison with placebo, was effective (a) in maintaining patients with no VPB (AMIOD 50% - PL 39%), (b) in diminishing VPB/hour (AMIOD 29% - PL 9%), and (c) in avoiding the increase of VPB/hour (AMIOD 79% - PL 48%). The authors finish their paper emphasizing that no antidysrhythmic drug should be introduced in clinical practice before being submitted to controlled studies with Holter electrocardiography. |
publishDate |
1980 |
dc.date.none.fl_str_mv |
1980-12-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4294 oai:ojs.www.actamedicaportuguesa.com:article/4294 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4294 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/4294 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4294 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4294/3384 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 2 (1980): Suplemento; 27-32 Acta Médica Portuguesa; Vol. 2 (1980): Suplemento; 27-32 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799130639757213696 |