Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.21/13586 |
Resumo: | Purpose: To evaluate the repeatability and reproducibility of the segmentation of 12 layers of the retina and the choroid, performed manually by SD-OCT, along the horizontal meridian at three different temporal moments, and to evaluate its concordance with the same measurements performed by two other operators in intermediate AMD. Methods: A cross-sectional study of 40 eyes from 40 subjects with intermediate AMD was conducted. The segmentation was performed manually, using SD-OCT. The 169 measurements per eye were repeated at three-time points to study the intra-operator variability. The same process was repeated a single time by two different trained operators for the inter-operator variability. Results: Forty participants (28 women and 12 men) were enrolled in this study, with an average age of 76.4 ± 8.2 (range, 55–92 years). Overall, the maximum values of the various structures were found in the 3 mm of the macula. Intra-operator variability: the highest ICC values turned out to be discovered in thicker locations. inter-operator variability: except correlation values of 0.826 (0.727; 0.898) obtained in the OPL (T2.5) and 0.634 (0.469; 0.771) obtained in the IPL (N2), all other correlation values were >0.92, in most cases approaching higher values like 0.98. Conclusion: The measurements of several layers of the retina and the choroid achieved at 13 locations presented good repeatability and reproducibility. Manual quantification is still an alternative for the weaknesses of automatic segmentation. Locations of greatest concordance should be those used for clinical control and monitoring. |
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Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibilityOphthalmologyOrthopticsData accuracyDiagnostic imagingMacular degenerationPurpose: To evaluate the repeatability and reproducibility of the segmentation of 12 layers of the retina and the choroid, performed manually by SD-OCT, along the horizontal meridian at three different temporal moments, and to evaluate its concordance with the same measurements performed by two other operators in intermediate AMD. Methods: A cross-sectional study of 40 eyes from 40 subjects with intermediate AMD was conducted. The segmentation was performed manually, using SD-OCT. The 169 measurements per eye were repeated at three-time points to study the intra-operator variability. The same process was repeated a single time by two different trained operators for the inter-operator variability. Results: Forty participants (28 women and 12 men) were enrolled in this study, with an average age of 76.4 ± 8.2 (range, 55–92 years). Overall, the maximum values of the various structures were found in the 3 mm of the macula. Intra-operator variability: the highest ICC values turned out to be discovered in thicker locations. inter-operator variability: except correlation values of 0.826 (0.727; 0.898) obtained in the OPL (T2.5) and 0.634 (0.469; 0.771) obtained in the IPL (N2), all other correlation values were >0.92, in most cases approaching higher values like 0.98. Conclusion: The measurements of several layers of the retina and the choroid achieved at 13 locations presented good repeatability and reproducibility. Manual quantification is still an alternative for the weaknesses of automatic segmentation. Locations of greatest concordance should be those used for clinical control and monitoring.Knowledge ERCIPLCamacho, PedroDutra-Medeiros, MarcoSalgueiro, LuísSadio, SílviaRosa, Paulo C.2021-07-30T08:44:51Z2021-072021-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/13586engCamacho P, Dutra-Medeiros M, Salgueiro L, Sadio S, Rosa PC. Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility. J Ophthalmic Vis Res. 2021;16(3):384-92.10.18502/jovr.v16i3.9435info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T10:08:35Zoai:repositorio.ipl.pt:10400.21/13586Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:21:30.411558Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility |
title |
Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility |
spellingShingle |
Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility Camacho, Pedro Ophthalmology Orthoptics Data accuracy Diagnostic imaging Macular degeneration |
title_short |
Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility |
title_full |
Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility |
title_fullStr |
Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility |
title_full_unstemmed |
Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility |
title_sort |
Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility |
author |
Camacho, Pedro |
author_facet |
Camacho, Pedro Dutra-Medeiros, Marco Salgueiro, Luís Sadio, Sílvia Rosa, Paulo C. |
author_role |
author |
author2 |
Dutra-Medeiros, Marco Salgueiro, Luís Sadio, Sílvia Rosa, Paulo C. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
RCIPL |
dc.contributor.author.fl_str_mv |
Camacho, Pedro Dutra-Medeiros, Marco Salgueiro, Luís Sadio, Sílvia Rosa, Paulo C. |
dc.subject.por.fl_str_mv |
Ophthalmology Orthoptics Data accuracy Diagnostic imaging Macular degeneration |
topic |
Ophthalmology Orthoptics Data accuracy Diagnostic imaging Macular degeneration |
description |
Purpose: To evaluate the repeatability and reproducibility of the segmentation of 12 layers of the retina and the choroid, performed manually by SD-OCT, along the horizontal meridian at three different temporal moments, and to evaluate its concordance with the same measurements performed by two other operators in intermediate AMD. Methods: A cross-sectional study of 40 eyes from 40 subjects with intermediate AMD was conducted. The segmentation was performed manually, using SD-OCT. The 169 measurements per eye were repeated at three-time points to study the intra-operator variability. The same process was repeated a single time by two different trained operators for the inter-operator variability. Results: Forty participants (28 women and 12 men) were enrolled in this study, with an average age of 76.4 ± 8.2 (range, 55–92 years). Overall, the maximum values of the various structures were found in the 3 mm of the macula. Intra-operator variability: the highest ICC values turned out to be discovered in thicker locations. inter-operator variability: except correlation values of 0.826 (0.727; 0.898) obtained in the OPL (T2.5) and 0.634 (0.469; 0.771) obtained in the IPL (N2), all other correlation values were >0.92, in most cases approaching higher values like 0.98. Conclusion: The measurements of several layers of the retina and the choroid achieved at 13 locations presented good repeatability and reproducibility. Manual quantification is still an alternative for the weaknesses of automatic segmentation. Locations of greatest concordance should be those used for clinical control and monitoring. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-07-30T08:44:51Z 2021-07 2021-07-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.21/13586 |
url |
http://hdl.handle.net/10400.21/13586 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Camacho P, Dutra-Medeiros M, Salgueiro L, Sadio S, Rosa PC. Manual segmentation of 12 layers of the retina and choroid through SD-OCT in intermediate AMD: repeatability and reproducibility. J Ophthalmic Vis Res. 2021;16(3):384-92. 10.18502/jovr.v16i3.9435 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Knowledge E |
publisher.none.fl_str_mv |
Knowledge E |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133486099988480 |