Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles

Detalhes bibliográficos
Autor(a) principal: Castro, Vânia I. B.
Data de Publicação: 2024
Outros Autores: Gao, Yuting, Brito, Alexandra, Chen, Jie, Reis, R. L., Pashkuleva, I., Pires, R. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/92220
Resumo: We show distinct CH-pi interactions and assembly pathways for the amphiphile N-(fluorenylmethoxycarbonyl)-galactosamine and its epimer N-(fluorenylmethoxycarbonyl)-glucosamine. These differences result in the formation of supramolecular nanofibrous systems with opposite chirality. Our results showcase the importance of the carbohydrates structural diversity for their specific biointeractions and the opportunity that their ample interactome offers for synthesis of versatile and tunable supramolecular (bio)materials.
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spelling Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphilesCarbohydratesHelicityIsomersNanofibersSelf-assemblySupramolecular polymerizationWe show distinct CH-pi interactions and assembly pathways for the amphiphile N-(fluorenylmethoxycarbonyl)-galactosamine and its epimer N-(fluorenylmethoxycarbonyl)-glucosamine. These differences result in the formation of supramolecular nanofibrous systems with opposite chirality. Our results showcase the importance of the carbohydrates structural diversity for their specific biointeractions and the opportunity that their ample interactome offers for synthesis of versatile and tunable supramolecular (bio)materials.We acknowledge the European Commission H2020 programme and the Portuguese Foundation for Science and Technology (FCT) for financial support: M-ERA-NET3/0007/2021 (RePark); RAP - CEECIND/05623/2022; VIBC – PD/BD/135256/2017; COVID/BD/152018/2021. We also acknowledge the project “TERM RES Hub – Scientific Infrastructure for Tissue Engineering and Regenerative Medicine” - PINFRA/22190/2016 (Norte-01-0145-FEDER-022190, co-funded by FCT and the Northern Portugal Regional Coordination and Development Commission, CCDR-N), for providing lab facilities, state-of-the art equipment and highly qualified human resources.Royal Society of ChemistryUniversidade do MinhoCastro, Vânia I. B.Gao, YutingBrito, AlexandraChen, JieReis, R. L.Pashkuleva, I.Pires, R. A.2024-062024-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/92220engCastro V. I. B., Gao Y., Brito A., Chen J., Reis R. L., Pashkuleva I., Pires R. A. Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles, Journal Of Materials Chemistry B, pp. in press, 2050-7518, 20242050-7518https://doi.org/10.1039/D4TB00728Jinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-08-03T01:26:12Zoai:repositorium.sdum.uminho.pt:1822/92220Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-08-03T01:26:12Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles
title Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles
spellingShingle Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles
Castro, Vânia I. B.
Carbohydrates
Helicity
Isomers
Nanofibers
Self-assembly
Supramolecular polymerization
title_short Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles
title_full Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles
title_fullStr Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles
title_full_unstemmed Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles
title_sort Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles
author Castro, Vânia I. B.
author_facet Castro, Vânia I. B.
Gao, Yuting
Brito, Alexandra
Chen, Jie
Reis, R. L.
Pashkuleva, I.
Pires, R. A.
author_role author
author2 Gao, Yuting
Brito, Alexandra
Chen, Jie
Reis, R. L.
Pashkuleva, I.
Pires, R. A.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Castro, Vânia I. B.
Gao, Yuting
Brito, Alexandra
Chen, Jie
Reis, R. L.
Pashkuleva, I.
Pires, R. A.
dc.subject.por.fl_str_mv Carbohydrates
Helicity
Isomers
Nanofibers
Self-assembly
Supramolecular polymerization
topic Carbohydrates
Helicity
Isomers
Nanofibers
Self-assembly
Supramolecular polymerization
description We show distinct CH-pi interactions and assembly pathways for the amphiphile N-(fluorenylmethoxycarbonyl)-galactosamine and its epimer N-(fluorenylmethoxycarbonyl)-glucosamine. These differences result in the formation of supramolecular nanofibrous systems with opposite chirality. Our results showcase the importance of the carbohydrates structural diversity for their specific biointeractions and the opportunity that their ample interactome offers for synthesis of versatile and tunable supramolecular (bio)materials.
publishDate 2024
dc.date.none.fl_str_mv 2024-06
2024-06-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/92220
url https://hdl.handle.net/1822/92220
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Castro V. I. B., Gao Y., Brito A., Chen J., Reis R. L., Pashkuleva I., Pires R. A. Cooling rate uncovers epimer-dependent supramolecular organization of carbohydrate amphiphiles, Journal Of Materials Chemistry B, pp. in press, 2050-7518, 2024
2050-7518
https://doi.org/10.1039/D4TB00728J
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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