Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemática

Detalhes bibliográficos
Autor(a) principal: Diogo Filipe Brandão Neves
Data de Publicação: 2021
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/134428
Resumo: Background: Acute Coronary Syndrome has a high incidence and is an important cause of death and morbidity at a national and European level. Chronic Insomnia might constitute a risk factor for its development, and if so, there could be a place for the inclusion of this pathology in the global primary prevention strategies, in Primary Healthcare. Method: A systematic review was conducted, searching for papers that investigated the potential impact of Chronic Insomnia on the development of Acute Coronary Syndrome, in Pubmed, Scopus and the specialized magazine SLEEP. Results: Five papers were included, involving over 900 000 individuals. The outcomes' definitions and the diagnosis criteria were different among the included studies, but all arrived at the conclusion of a statistically significative effect (totality of the population or subgroups only) before adjusting for confounding variables and, of these, four out of five arrived at the same conclusion after adjusting. Two of the studies also investigated the potential of sex as an effect modifier. Discussion: The existence of the studied association is possible. Nevertheless, it was impossible for us to conclude with certainty its veracity, due to the fact that we did not obtain an aggregated measure of outcome (differences in outcome measures and population's characteristics) and because several of the causality criteria were not fulfilled. Conclusion: There seems to be an association between Chronic Insomnia and the onset of Acute Coronary Syndrome, but there is a need for more studies to be developed, with well-established diagnosis criteria and uniform outcome measures.
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spelling Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemáticaMedicina clínicaClinical medicineBackground: Acute Coronary Syndrome has a high incidence and is an important cause of death and morbidity at a national and European level. Chronic Insomnia might constitute a risk factor for its development, and if so, there could be a place for the inclusion of this pathology in the global primary prevention strategies, in Primary Healthcare. Method: A systematic review was conducted, searching for papers that investigated the potential impact of Chronic Insomnia on the development of Acute Coronary Syndrome, in Pubmed, Scopus and the specialized magazine SLEEP. Results: Five papers were included, involving over 900 000 individuals. The outcomes' definitions and the diagnosis criteria were different among the included studies, but all arrived at the conclusion of a statistically significative effect (totality of the population or subgroups only) before adjusting for confounding variables and, of these, four out of five arrived at the same conclusion after adjusting. Two of the studies also investigated the potential of sex as an effect modifier. Discussion: The existence of the studied association is possible. Nevertheless, it was impossible for us to conclude with certainty its veracity, due to the fact that we did not obtain an aggregated measure of outcome (differences in outcome measures and population's characteristics) and because several of the causality criteria were not fulfilled. Conclusion: There seems to be an association between Chronic Insomnia and the onset of Acute Coronary Syndrome, but there is a need for more studies to be developed, with well-established diagnosis criteria and uniform outcome measures.2021-05-172021-05-17T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://hdl.handle.net/10216/134428TID:202848434porDiogo Filipe Brandão Nevesinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T15:38:36Zoai:repositorio-aberto.up.pt:10216/134428Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:28:37.022099Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemática
title Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemática
spellingShingle Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemática
Diogo Filipe Brandão Neves
Medicina clínica
Clinical medicine
title_short Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemática
title_full Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemática
title_fullStr Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemática
title_full_unstemmed Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemática
title_sort Insónia Crónica e o seu potencial impacto no desenvolvimento de Síndrome Coronário Agudo - uma revisão sistemática
author Diogo Filipe Brandão Neves
author_facet Diogo Filipe Brandão Neves
author_role author
dc.contributor.author.fl_str_mv Diogo Filipe Brandão Neves
dc.subject.por.fl_str_mv Medicina clínica
Clinical medicine
topic Medicina clínica
Clinical medicine
description Background: Acute Coronary Syndrome has a high incidence and is an important cause of death and morbidity at a national and European level. Chronic Insomnia might constitute a risk factor for its development, and if so, there could be a place for the inclusion of this pathology in the global primary prevention strategies, in Primary Healthcare. Method: A systematic review was conducted, searching for papers that investigated the potential impact of Chronic Insomnia on the development of Acute Coronary Syndrome, in Pubmed, Scopus and the specialized magazine SLEEP. Results: Five papers were included, involving over 900 000 individuals. The outcomes' definitions and the diagnosis criteria were different among the included studies, but all arrived at the conclusion of a statistically significative effect (totality of the population or subgroups only) before adjusting for confounding variables and, of these, four out of five arrived at the same conclusion after adjusting. Two of the studies also investigated the potential of sex as an effect modifier. Discussion: The existence of the studied association is possible. Nevertheless, it was impossible for us to conclude with certainty its veracity, due to the fact that we did not obtain an aggregated measure of outcome (differences in outcome measures and population's characteristics) and because several of the causality criteria were not fulfilled. Conclusion: There seems to be an association between Chronic Insomnia and the onset of Acute Coronary Syndrome, but there is a need for more studies to be developed, with well-established diagnosis criteria and uniform outcome measures.
publishDate 2021
dc.date.none.fl_str_mv 2021-05-17
2021-05-17T00:00:00Z
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