Biochemical endpoints on juvenile Solea senegalensis exposed
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.2/1399 |
Resumo: | Juvenile Solea senegalensis were exposed to fresh sediments from three stations of the Sado estuary (Portugal) in 28-day laboratory assays. Sediments revealed distinct levels of total organic matter, fine fraction, redox potential, trace elements (arsenic, cadmium, chromium, copper, nickel, lead and zinc) and organic contaminants (polycyclic aromatic hydrocarbons, polychlorinated biphenyls and a pesticide: dichloro diphenyl trichloroethane). Organisms were surveyed for contaminant bioaccumulation and induction of two hepatic biochemical biomarkers: metallothionein (MT) and cytochrome P450 (CYP1A), as potential indicators of exposure to metallic and organic contaminants, respectively. Using an integrative approach it was established that, although bioaccumulation is in general accordance with sediment contamination, lethality and biomarker responses are not linearly dependent of the cumulative concentrations of sediment contaminants but rather of their bioavailability and synergistic effects in organisms. It is concluded that metals and organic contaminants modulate both MT and CYP1A induction and it is suggested that reactive oxygen species may be the link between responses and effects of toxicity. |
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Biochemical endpoints on juvenile Solea senegalensis exposedSenegalese soleContaminated sedimentsBioaccumulationMetallothioneinCYP1ASado estuaryODS::03:Saúde de QualidadeJuvenile Solea senegalensis were exposed to fresh sediments from three stations of the Sado estuary (Portugal) in 28-day laboratory assays. Sediments revealed distinct levels of total organic matter, fine fraction, redox potential, trace elements (arsenic, cadmium, chromium, copper, nickel, lead and zinc) and organic contaminants (polycyclic aromatic hydrocarbons, polychlorinated biphenyls and a pesticide: dichloro diphenyl trichloroethane). Organisms were surveyed for contaminant bioaccumulation and induction of two hepatic biochemical biomarkers: metallothionein (MT) and cytochrome P450 (CYP1A), as potential indicators of exposure to metallic and organic contaminants, respectively. Using an integrative approach it was established that, although bioaccumulation is in general accordance with sediment contamination, lethality and biomarker responses are not linearly dependent of the cumulative concentrations of sediment contaminants but rather of their bioavailability and synergistic effects in organisms. It is concluded that metals and organic contaminants modulate both MT and CYP1A induction and it is suggested that reactive oxygen species may be the link between responses and effects of toxicity.SpringerRepositório AbertoCosta, Pedro M.Caeiro, SandraDiniz, Mário S.Lobo, JorgeMartins, MartaFerreira, Ana M.Caetano, MiguelVale, CarlosDelValls, T. ÁngelCosta, Maria Helena2009-10-22T13:25:50Z20092009-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.2/1399engCaeiro, Sandra [et al.] - Biochemical endpoints on juvenile Solea senegalensis exposed. "Ecotoxicology" [Em linha]. ISSN 0963-9292 (Print) 1573-3017 (Online). Nº 18 (2009), p. 988–10000963-9292 (Print)info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-16T15:13:56Zoai:repositorioaberto.uab.pt:10400.2/1399Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:43:15.123595Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Biochemical endpoints on juvenile Solea senegalensis exposed |
title |
Biochemical endpoints on juvenile Solea senegalensis exposed |
spellingShingle |
Biochemical endpoints on juvenile Solea senegalensis exposed Costa, Pedro M. Senegalese sole Contaminated sediments Bioaccumulation Metallothionein CYP1A Sado estuary ODS::03:Saúde de Qualidade |
title_short |
Biochemical endpoints on juvenile Solea senegalensis exposed |
title_full |
Biochemical endpoints on juvenile Solea senegalensis exposed |
title_fullStr |
Biochemical endpoints on juvenile Solea senegalensis exposed |
title_full_unstemmed |
Biochemical endpoints on juvenile Solea senegalensis exposed |
title_sort |
Biochemical endpoints on juvenile Solea senegalensis exposed |
author |
Costa, Pedro M. |
author_facet |
Costa, Pedro M. Caeiro, Sandra Diniz, Mário S. Lobo, Jorge Martins, Marta Ferreira, Ana M. Caetano, Miguel Vale, Carlos DelValls, T. Ángel Costa, Maria Helena |
author_role |
author |
author2 |
Caeiro, Sandra Diniz, Mário S. Lobo, Jorge Martins, Marta Ferreira, Ana M. Caetano, Miguel Vale, Carlos DelValls, T. Ángel Costa, Maria Helena |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Aberto |
dc.contributor.author.fl_str_mv |
Costa, Pedro M. Caeiro, Sandra Diniz, Mário S. Lobo, Jorge Martins, Marta Ferreira, Ana M. Caetano, Miguel Vale, Carlos DelValls, T. Ángel Costa, Maria Helena |
dc.subject.por.fl_str_mv |
Senegalese sole Contaminated sediments Bioaccumulation Metallothionein CYP1A Sado estuary ODS::03:Saúde de Qualidade |
topic |
Senegalese sole Contaminated sediments Bioaccumulation Metallothionein CYP1A Sado estuary ODS::03:Saúde de Qualidade |
description |
Juvenile Solea senegalensis were exposed to fresh sediments from three stations of the Sado estuary (Portugal) in 28-day laboratory assays. Sediments revealed distinct levels of total organic matter, fine fraction, redox potential, trace elements (arsenic, cadmium, chromium, copper, nickel, lead and zinc) and organic contaminants (polycyclic aromatic hydrocarbons, polychlorinated biphenyls and a pesticide: dichloro diphenyl trichloroethane). Organisms were surveyed for contaminant bioaccumulation and induction of two hepatic biochemical biomarkers: metallothionein (MT) and cytochrome P450 (CYP1A), as potential indicators of exposure to metallic and organic contaminants, respectively. Using an integrative approach it was established that, although bioaccumulation is in general accordance with sediment contamination, lethality and biomarker responses are not linearly dependent of the cumulative concentrations of sediment contaminants but rather of their bioavailability and synergistic effects in organisms. It is concluded that metals and organic contaminants modulate both MT and CYP1A induction and it is suggested that reactive oxygen species may be the link between responses and effects of toxicity. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-10-22T13:25:50Z 2009 2009-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.2/1399 |
url |
http://hdl.handle.net/10400.2/1399 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Caeiro, Sandra [et al.] - Biochemical endpoints on juvenile Solea senegalensis exposed. "Ecotoxicology" [Em linha]. ISSN 0963-9292 (Print) 1573-3017 (Online). Nº 18 (2009), p. 988–1000 0963-9292 (Print) |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Springer |
publisher.none.fl_str_mv |
Springer |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799134998957129728 |