Bull ́s Eye Maculopathy in a patient treated with efavirenz

Detalhes bibliográficos
Autor(a) principal: Vaz Pereira, Cristina
Data de Publicação: 2015
Outros Autores: Franco, Mónica, Guerra Pinto, Rita, Barrão, Sandra, Prior Filipe, Helena
Tipo de documento: Relatório
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.48560/rspo.6860
Resumo: Objective: To report a case of retinal toxicity associated with efavirenz in an adult. Methods: We describe a case of gradual-onset blurry vision in both eyes in a 37-year-old HIV caucasian woman, on antiretroviral therapy (ART), including efavirenz. Results: The patient presented with a best corrected visual acuity of 20/100 for the right eye (RE) and 20/125 for the left eye (LE). Fundoscopy revealed mottled atrophic changes of the macular retinal pigment epi- thelium (RPE) in both eyes. Fluorescein angiography revealed an annular pattern of RPE atrophy in both eyes. Full-field electretinography (ERG) was normal. Conclusions: Based on our patient ́s history and on previous reports, efavirenz seems to be the culprit in this case. Our report provides evidence in support of routine ophthalmological evalua- tion of patients on efavirenz.
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spelling Bull ́s Eye Maculopathy in a patient treated with efavirenzComunicações Curtas e Imagens em OftalmologiaObjective: To report a case of retinal toxicity associated with efavirenz in an adult. Methods: We describe a case of gradual-onset blurry vision in both eyes in a 37-year-old HIV caucasian woman, on antiretroviral therapy (ART), including efavirenz. Results: The patient presented with a best corrected visual acuity of 20/100 for the right eye (RE) and 20/125 for the left eye (LE). Fundoscopy revealed mottled atrophic changes of the macular retinal pigment epi- thelium (RPE) in both eyes. Fluorescein angiography revealed an annular pattern of RPE atrophy in both eyes. Full-field electretinography (ERG) was normal. Conclusions: Based on our patient ́s history and on previous reports, efavirenz seems to be the culprit in this case. Our report provides evidence in support of routine ophthalmological evalua- tion of patients on efavirenz.Ajnet2015-12-25T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporthttps://doi.org/10.48560/rspo.6860por1646-69501646-6950Vaz Pereira, CristinaFranco, MónicaGuerra Pinto, RitaBarrão, SandraPrior Filipe, Helenainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-22T17:05:52Zoai:ojs.revistas.rcaap.pt:article/6860Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:01:33.707060Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bull ́s Eye Maculopathy in a patient treated with efavirenz
title Bull ́s Eye Maculopathy in a patient treated with efavirenz
spellingShingle Bull ́s Eye Maculopathy in a patient treated with efavirenz
Vaz Pereira, Cristina
Comunicações Curtas e Imagens em Oftalmologia
title_short Bull ́s Eye Maculopathy in a patient treated with efavirenz
title_full Bull ́s Eye Maculopathy in a patient treated with efavirenz
title_fullStr Bull ́s Eye Maculopathy in a patient treated with efavirenz
title_full_unstemmed Bull ́s Eye Maculopathy in a patient treated with efavirenz
title_sort Bull ́s Eye Maculopathy in a patient treated with efavirenz
author Vaz Pereira, Cristina
author_facet Vaz Pereira, Cristina
Franco, Mónica
Guerra Pinto, Rita
Barrão, Sandra
Prior Filipe, Helena
author_role author
author2 Franco, Mónica
Guerra Pinto, Rita
Barrão, Sandra
Prior Filipe, Helena
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Vaz Pereira, Cristina
Franco, Mónica
Guerra Pinto, Rita
Barrão, Sandra
Prior Filipe, Helena
dc.subject.por.fl_str_mv Comunicações Curtas e Imagens em Oftalmologia
topic Comunicações Curtas e Imagens em Oftalmologia
description Objective: To report a case of retinal toxicity associated with efavirenz in an adult. Methods: We describe a case of gradual-onset blurry vision in both eyes in a 37-year-old HIV caucasian woman, on antiretroviral therapy (ART), including efavirenz. Results: The patient presented with a best corrected visual acuity of 20/100 for the right eye (RE) and 20/125 for the left eye (LE). Fundoscopy revealed mottled atrophic changes of the macular retinal pigment epi- thelium (RPE) in both eyes. Fluorescein angiography revealed an annular pattern of RPE atrophy in both eyes. Full-field electretinography (ERG) was normal. Conclusions: Based on our patient ́s history and on previous reports, efavirenz seems to be the culprit in this case. Our report provides evidence in support of routine ophthalmological evalua- tion of patients on efavirenz.
publishDate 2015
dc.date.none.fl_str_mv 2015-12-25T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
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status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.48560/rspo.6860
url https://doi.org/10.48560/rspo.6860
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv 1646-6950
1646-6950
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instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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