Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)

Detalhes bibliográficos
Autor(a) principal: Diogo Gonçalo Silva Freitas
Data de Publicação: 2020
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/128852
Resumo: Laser and Vaginal Brachytherapy showed a maximum 93% and 100% Cure Rate (CR), respectively, with a significant Persistence Rate (PR) up to 100% and 0-59% Recurrence Rate (RR). Laser has few complications and is indicated for sexually active women. Brachytherapy, due to toxicity, should be reserved for high-grade and refractory lesions. Imiquimod and 5-Flouorouracil revealed a 25-82% CR, 26-75% PR, 6-94% RR and are indicated in multifocal lesions. Expectant management has 44-60% CR with PR and RR up to 50%. In contrast to low-grade lesions, high-grade lesions require treatment which should be selected depending on its characteristics and the patient's.
id RCAP_1479d10ac2be095c5f6f0a7c350b72fa
oai_identifier_str oai:repositorio-aberto.up.pt:10216/128852
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)Ciências médicas e da saúdeMedical and Health sciencesLaser and Vaginal Brachytherapy showed a maximum 93% and 100% Cure Rate (CR), respectively, with a significant Persistence Rate (PR) up to 100% and 0-59% Recurrence Rate (RR). Laser has few complications and is indicated for sexually active women. Brachytherapy, due to toxicity, should be reserved for high-grade and refractory lesions. Imiquimod and 5-Flouorouracil revealed a 25-82% CR, 26-75% PR, 6-94% RR and are indicated in multifocal lesions. Expectant management has 44-60% CR with PR and RR up to 50%. In contrast to low-grade lesions, high-grade lesions require treatment which should be selected depending on its characteristics and the patient's.2020-05-292020-05-29T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://hdl.handle.net/10216/128852TID:202613305engDiogo Gonçalo Silva Freitasinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T14:59:45Zoai:repositorio-aberto.up.pt:10216/128852Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:13:15.574039Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)
title Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)
spellingShingle Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)
Diogo Gonçalo Silva Freitas
Ciências médicas e da saúde
Medical and Health sciences
title_short Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)
title_full Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)
title_fullStr Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)
title_full_unstemmed Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)
title_sort Non-invasive treatment modalities for Vaginal Intraepithelial Neoplasia (VaIN)
author Diogo Gonçalo Silva Freitas
author_facet Diogo Gonçalo Silva Freitas
author_role author
dc.contributor.author.fl_str_mv Diogo Gonçalo Silva Freitas
dc.subject.por.fl_str_mv Ciências médicas e da saúde
Medical and Health sciences
topic Ciências médicas e da saúde
Medical and Health sciences
description Laser and Vaginal Brachytherapy showed a maximum 93% and 100% Cure Rate (CR), respectively, with a significant Persistence Rate (PR) up to 100% and 0-59% Recurrence Rate (RR). Laser has few complications and is indicated for sexually active women. Brachytherapy, due to toxicity, should be reserved for high-grade and refractory lesions. Imiquimod and 5-Flouorouracil revealed a 25-82% CR, 26-75% PR, 6-94% RR and are indicated in multifocal lesions. Expectant management has 44-60% CR with PR and RR up to 50%. In contrast to low-grade lesions, high-grade lesions require treatment which should be selected depending on its characteristics and the patient's.
publishDate 2020
dc.date.none.fl_str_mv 2020-05-29
2020-05-29T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10216/128852
TID:202613305
url https://hdl.handle.net/10216/128852
identifier_str_mv TID:202613305
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799136054343630848

Registros relacionados