An Extreme Case of Liver Adenomatosis

Detalhes bibliográficos
Autor(a) principal: Chálim Rebelo, Carolina
Data de Publicação: 2022
Outros Autores: Moura, Diogo Bernardo, Flor de Lima, Margarida, Dutra, Eduardo, Amaral, Rui, Pereira, José Renato, Duarte, Maria Antónia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/134688
Resumo: Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
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spelling An Extreme Case of Liver AdenomatosisAre They All the Same?Hepatocellular adenomaInflammatory subtypeLiver adenomatosisLiver nodulesHepatologyGastroenterologyPublisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Hepatocellular adenoma (HCA) is a rare and benign liver tumor that affects predominantly young and middle-aged women, especially between 30–40 years old. Liver adenomatosis (LA) is defined as the presence of 10 or more HCA. There are authors that report eight different subtypes of HCA, that correlates with clinical and histopathological features, being the inflammatory subtype the most common. We present a case of a 32-year-old Caucasian woman with a history of self-limited episodes of right abdominal pain and an abdominal ultrasound with multiple hypoechogenic liver nodules, suspected of metastasis. She was taking combined oral contraceptive for 6 years. Magnetic Resonance Imaging (MRI) disclosed around 40 nodules, suggestive of HCA. Liver biopsy confirmed HCA, inflammatory subtype. Oral contraceptive was stopped and control MRI 6 months later disclosed reduction of nodules’ dimensions. Management of patients with LA should be based on the size of the largest tumor, as clinical presentation and risk of bleeding or malignancy do not differ between patients with single or multiple HCAs. However, even with biopsy, there is a risk of missampling, raising concern about the real risk of bleeding and malignant potential in patients with different subtypes coexisting in the same liver.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNChálim Rebelo, CarolinaMoura, Diogo BernardoFlor de Lima, MargaridaDutra, EduardoAmaral, RuiPereira, José RenatoDuarte, Maria Antónia2022-03-16T23:23:27Z2022-032022-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9application/pdfhttp://hdl.handle.net/10362/134688engPURE: 42090366https://doi.org/10.3390/gastroent13010008info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:13:09Zoai:run.unl.pt:10362/134688Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:48:12.087155Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv An Extreme Case of Liver Adenomatosis
Are They All the Same?
title An Extreme Case of Liver Adenomatosis
spellingShingle An Extreme Case of Liver Adenomatosis
Chálim Rebelo, Carolina
Hepatocellular adenoma
Inflammatory subtype
Liver adenomatosis
Liver nodules
Hepatology
Gastroenterology
title_short An Extreme Case of Liver Adenomatosis
title_full An Extreme Case of Liver Adenomatosis
title_fullStr An Extreme Case of Liver Adenomatosis
title_full_unstemmed An Extreme Case of Liver Adenomatosis
title_sort An Extreme Case of Liver Adenomatosis
author Chálim Rebelo, Carolina
author_facet Chálim Rebelo, Carolina
Moura, Diogo Bernardo
Flor de Lima, Margarida
Dutra, Eduardo
Amaral, Rui
Pereira, José Renato
Duarte, Maria Antónia
author_role author
author2 Moura, Diogo Bernardo
Flor de Lima, Margarida
Dutra, Eduardo
Amaral, Rui
Pereira, José Renato
Duarte, Maria Antónia
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Chálim Rebelo, Carolina
Moura, Diogo Bernardo
Flor de Lima, Margarida
Dutra, Eduardo
Amaral, Rui
Pereira, José Renato
Duarte, Maria Antónia
dc.subject.por.fl_str_mv Hepatocellular adenoma
Inflammatory subtype
Liver adenomatosis
Liver nodules
Hepatology
Gastroenterology
topic Hepatocellular adenoma
Inflammatory subtype
Liver adenomatosis
Liver nodules
Hepatology
Gastroenterology
description Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-16T23:23:27Z
2022-03
2022-03-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/134688
url http://hdl.handle.net/10362/134688
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv PURE: 42090366
https://doi.org/10.3390/gastroent13010008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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