Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/6660 |
Resumo: | This study examined the phytochemical profiles (mainly phenolics, carotenoids, and organosulfur compounds) and biological effects of hydroalcoholic extracts of Allium flavum (AF), a species of the Allium genus commonly known as small yellow onion. Unsupervised and supervised statistical approaches revealed clear differences between extracts prepared with samples collected from different areas of Romania. Overall, the AFFF (AF flowers collected from Faget) extract was the best source of polyphenols, also showing the highest antioxidant capacity evaluated through both in vitro DPPH, FRAP, and TEAC anti-radical scavenging assays and cell-based OxHLIA and TBARS assays. All the tested extracts exhibited & alpha;-glucosidase inhibition potential, while only the AFFF extract exhibited anti-lipase inhibitory activity. The phenolic subclasses annotated were positively correlated with the assessed antioxidant and enzyme inhibitory activities. Our findings suggested that A. flavum has bioactive properties worth exploring further, being a potential edible flower with health-promoting implications. |
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Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of RomaniaAllium flavumCarotenoidsEnzyme inhibitionFunctional componentsMetabolomicsPolyphenolsSulfur compoundsThis study examined the phytochemical profiles (mainly phenolics, carotenoids, and organosulfur compounds) and biological effects of hydroalcoholic extracts of Allium flavum (AF), a species of the Allium genus commonly known as small yellow onion. Unsupervised and supervised statistical approaches revealed clear differences between extracts prepared with samples collected from different areas of Romania. Overall, the AFFF (AF flowers collected from Faget) extract was the best source of polyphenols, also showing the highest antioxidant capacity evaluated through both in vitro DPPH, FRAP, and TEAC anti-radical scavenging assays and cell-based OxHLIA and TBARS assays. All the tested extracts exhibited & alpha;-glucosidase inhibition potential, while only the AFFF extract exhibited anti-lipase inhibitory activity. The phenolic subclasses annotated were positively correlated with the assessed antioxidant and enzyme inhibitory activities. Our findings suggested that A. flavum has bioactive properties worth exploring further, being a potential edible flower with health-promoting implications.This work was supported by a grant from the Romanian Ministry of Education and Research, CCCDI—UEFISCDI, project number PN-III-P2- 2.1-PED-2019-5360, within PNCDI III. To Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES (PIDDAC) to CIMO (UIDB/00690/2020 and UIDP/00690/ 2020) and SusTEC (LA/P/0007/2020) and for the contracts of J. Pinela (CEECIND/01011/2018) and L. Barros (CEEC Institutional).ElsevierBiblioteca Digital do IPBMoldovan, CadmielFrumuzachi, OlegBabotă, MihaiPinela, JoséBarros, LillianRocchetti, GabrieleLopez, VictorLucini, LuigiCrisan, GianinaMocan, Andrei2012-02-27T11:47:12Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/6660engMoldovan, Cadmiel; Frumuzachi, Oleg; Babotă, Mihai; Pinela, José; Barros, Lillian; Rocchetti, Gabriele; Lopez, Victor; Lucini, Luigi; Crisan, Gianina; Mocan, Andrei (2023). Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania. Food Chemistry. eISSN 1873-7072. 426, p. 1-80308-814610.1016/j.foodchem.2023.1365031873-7072info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-13T01:18:00Zoai:bibliotecadigital.ipb.pt:10198/6660Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:42:16.986101Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania |
title |
Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania |
spellingShingle |
Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania Moldovan, Cadmiel Allium flavum Carotenoids Enzyme inhibition Functional components Metabolomics Polyphenols Sulfur compounds |
title_short |
Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania |
title_full |
Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania |
title_fullStr |
Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania |
title_full_unstemmed |
Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania |
title_sort |
Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania |
author |
Moldovan, Cadmiel |
author_facet |
Moldovan, Cadmiel Frumuzachi, Oleg Babotă, Mihai Pinela, José Barros, Lillian Rocchetti, Gabriele Lopez, Victor Lucini, Luigi Crisan, Gianina Mocan, Andrei |
author_role |
author |
author2 |
Frumuzachi, Oleg Babotă, Mihai Pinela, José Barros, Lillian Rocchetti, Gabriele Lopez, Victor Lucini, Luigi Crisan, Gianina Mocan, Andrei |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Moldovan, Cadmiel Frumuzachi, Oleg Babotă, Mihai Pinela, José Barros, Lillian Rocchetti, Gabriele Lopez, Victor Lucini, Luigi Crisan, Gianina Mocan, Andrei |
dc.subject.por.fl_str_mv |
Allium flavum Carotenoids Enzyme inhibition Functional components Metabolomics Polyphenols Sulfur compounds |
topic |
Allium flavum Carotenoids Enzyme inhibition Functional components Metabolomics Polyphenols Sulfur compounds |
description |
This study examined the phytochemical profiles (mainly phenolics, carotenoids, and organosulfur compounds) and biological effects of hydroalcoholic extracts of Allium flavum (AF), a species of the Allium genus commonly known as small yellow onion. Unsupervised and supervised statistical approaches revealed clear differences between extracts prepared with samples collected from different areas of Romania. Overall, the AFFF (AF flowers collected from Faget) extract was the best source of polyphenols, also showing the highest antioxidant capacity evaluated through both in vitro DPPH, FRAP, and TEAC anti-radical scavenging assays and cell-based OxHLIA and TBARS assays. All the tested extracts exhibited & alpha;-glucosidase inhibition potential, while only the AFFF extract exhibited anti-lipase inhibitory activity. The phenolic subclasses annotated were positively correlated with the assessed antioxidant and enzyme inhibitory activities. Our findings suggested that A. flavum has bioactive properties worth exploring further, being a potential edible flower with health-promoting implications. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-02-27T11:47:12Z 2023 2023-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/6660 |
url |
http://hdl.handle.net/10198/6660 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Moldovan, Cadmiel; Frumuzachi, Oleg; Babotă, Mihai; Pinela, José; Barros, Lillian; Rocchetti, Gabriele; Lopez, Victor; Lucini, Luigi; Crisan, Gianina; Mocan, Andrei (2023). Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania. Food Chemistry. eISSN 1873-7072. 426, p. 1-8 0308-8146 10.1016/j.foodchem.2023.136503 1873-7072 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799136324196761600 |