Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania

Detalhes bibliográficos
Autor(a) principal: Moldovan, Cadmiel
Data de Publicação: 2012
Outros Autores: Frumuzachi, Oleg, Babotă, Mihai, Pinela, José, Barros, Lillian, Rocchetti, Gabriele, Lopez, Victor, Lucini, Luigi, Crisan, Gianina, Mocan, Andrei
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/6660
Resumo: This study examined the phytochemical profiles (mainly phenolics, carotenoids, and organosulfur compounds) and biological effects of hydroalcoholic extracts of Allium flavum (AF), a species of the Allium genus commonly known as small yellow onion. Unsupervised and supervised statistical approaches revealed clear differences between extracts prepared with samples collected from different areas of Romania. Overall, the AFFF (AF flowers collected from Faget) extract was the best source of polyphenols, also showing the highest antioxidant capacity evaluated through both in vitro DPPH, FRAP, and TEAC anti-radical scavenging assays and cell-based OxHLIA and TBARS assays. All the tested extracts exhibited & alpha;-glucosidase inhibition potential, while only the AFFF extract exhibited anti-lipase inhibitory activity. The phenolic subclasses annotated were positively correlated with the assessed antioxidant and enzyme inhibitory activities. Our findings suggested that A. flavum has bioactive properties worth exploring further, being a potential edible flower with health-promoting implications.
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spelling Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of RomaniaAllium flavumCarotenoidsEnzyme inhibitionFunctional componentsMetabolomicsPolyphenolsSulfur compoundsThis study examined the phytochemical profiles (mainly phenolics, carotenoids, and organosulfur compounds) and biological effects of hydroalcoholic extracts of Allium flavum (AF), a species of the Allium genus commonly known as small yellow onion. Unsupervised and supervised statistical approaches revealed clear differences between extracts prepared with samples collected from different areas of Romania. Overall, the AFFF (AF flowers collected from Faget) extract was the best source of polyphenols, also showing the highest antioxidant capacity evaluated through both in vitro DPPH, FRAP, and TEAC anti-radical scavenging assays and cell-based OxHLIA and TBARS assays. All the tested extracts exhibited & alpha;-glucosidase inhibition potential, while only the AFFF extract exhibited anti-lipase inhibitory activity. The phenolic subclasses annotated were positively correlated with the assessed antioxidant and enzyme inhibitory activities. Our findings suggested that A. flavum has bioactive properties worth exploring further, being a potential edible flower with health-promoting implications.This work was supported by a grant from the Romanian Ministry of Education and Research, CCCDI—UEFISCDI, project number PN-III-P2- 2.1-PED-2019-5360, within PNCDI III. To Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES (PIDDAC) to CIMO (UIDB/00690/2020 and UIDP/00690/ 2020) and SusTEC (LA/P/0007/2020) and for the contracts of J. Pinela (CEECIND/01011/2018) and L. Barros (CEEC Institutional).ElsevierBiblioteca Digital do IPBMoldovan, CadmielFrumuzachi, OlegBabotă, MihaiPinela, JoséBarros, LillianRocchetti, GabrieleLopez, VictorLucini, LuigiCrisan, GianinaMocan, Andrei2012-02-27T11:47:12Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/6660engMoldovan, Cadmiel; Frumuzachi, Oleg; Babotă, Mihai; Pinela, José; Barros, Lillian; Rocchetti, Gabriele; Lopez, Victor; Lucini, Luigi; Crisan, Gianina; Mocan, Andrei (2023). Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania. Food Chemistry. eISSN 1873-7072. 426, p. 1-80308-814610.1016/j.foodchem.2023.1365031873-7072info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-13T01:18:00Zoai:bibliotecadigital.ipb.pt:10198/6660Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:42:16.986101Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania
title Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania
spellingShingle Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania
Moldovan, Cadmiel
Allium flavum
Carotenoids
Enzyme inhibition
Functional components
Metabolomics
Polyphenols
Sulfur compounds
title_short Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania
title_full Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania
title_fullStr Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania
title_full_unstemmed Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania
title_sort Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania
author Moldovan, Cadmiel
author_facet Moldovan, Cadmiel
Frumuzachi, Oleg
Babotă, Mihai
Pinela, José
Barros, Lillian
Rocchetti, Gabriele
Lopez, Victor
Lucini, Luigi
Crisan, Gianina
Mocan, Andrei
author_role author
author2 Frumuzachi, Oleg
Babotă, Mihai
Pinela, José
Barros, Lillian
Rocchetti, Gabriele
Lopez, Victor
Lucini, Luigi
Crisan, Gianina
Mocan, Andrei
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Moldovan, Cadmiel
Frumuzachi, Oleg
Babotă, Mihai
Pinela, José
Barros, Lillian
Rocchetti, Gabriele
Lopez, Victor
Lucini, Luigi
Crisan, Gianina
Mocan, Andrei
dc.subject.por.fl_str_mv Allium flavum
Carotenoids
Enzyme inhibition
Functional components
Metabolomics
Polyphenols
Sulfur compounds
topic Allium flavum
Carotenoids
Enzyme inhibition
Functional components
Metabolomics
Polyphenols
Sulfur compounds
description This study examined the phytochemical profiles (mainly phenolics, carotenoids, and organosulfur compounds) and biological effects of hydroalcoholic extracts of Allium flavum (AF), a species of the Allium genus commonly known as small yellow onion. Unsupervised and supervised statistical approaches revealed clear differences between extracts prepared with samples collected from different areas of Romania. Overall, the AFFF (AF flowers collected from Faget) extract was the best source of polyphenols, also showing the highest antioxidant capacity evaluated through both in vitro DPPH, FRAP, and TEAC anti-radical scavenging assays and cell-based OxHLIA and TBARS assays. All the tested extracts exhibited & alpha;-glucosidase inhibition potential, while only the AFFF extract exhibited anti-lipase inhibitory activity. The phenolic subclasses annotated were positively correlated with the assessed antioxidant and enzyme inhibitory activities. Our findings suggested that A. flavum has bioactive properties worth exploring further, being a potential edible flower with health-promoting implications.
publishDate 2012
dc.date.none.fl_str_mv 2012-02-27T11:47:12Z
2023
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/6660
url http://hdl.handle.net/10198/6660
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Moldovan, Cadmiel; Frumuzachi, Oleg; Babotă, Mihai; Pinela, José; Barros, Lillian; Rocchetti, Gabriele; Lopez, Victor; Lucini, Luigi; Crisan, Gianina; Mocan, Andrei (2023). Untargeted phytochemical profiling and biological activity of small yellow onion (Allium flavum L.) from different regions of Romania. Food Chemistry. eISSN 1873-7072. 426, p. 1-8
0308-8146
10.1016/j.foodchem.2023.136503
1873-7072
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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