Executive functions and insight in OCD : a comparative study

Detalhes bibliográficos
Autor(a) principal: Manarte, Lucas
Data de Publicação: 2021
Outros Autores: Andrade, António R., Rosário, Linete do, Sampaio, Daniel, Figueira, Maria Luísa, Morgado, Pedro, Sahakian, Barbara J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/48013
Resumo: © The Author(s). 2021. This article is licensed under a Creative Commons Attribution 4.0 International License.
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spelling Executive functions and insight in OCD : a comparative studyExecutive functionsInsightObsessive-compulsive disorderTrail-making testVerbal memoryWisconsin card sorting Test© The Author(s). 2021. This article is licensed under a Creative Commons Attribution 4.0 International License.Background: Around 25 to 30% of patients with obsessive-compulsive disorder (OCD) do not respond to treatment. These patients have the longest duration of disease and the worst prognosis. Following years of research on this topic, insight has emerged as a potential explanation for this therapeutic resistance. Therefore, it has become important to characterize OCD patients with poor insight. Few studies have focused on the neuropsychological and cognitive characteristics of these patients. Methods: To help fill this gap, we divided 57 patients into two groups, one with good insight and the other with poor insight, assessed their neuropsychological functions-through a Rey's figure test, a California verbal learning test, a Toulouse-Piéron test and a Wisconsin Card Sorting Test (WCST)-and compared the results with those of a paired control group. Results: The statistical analysis, with a significance level of 95%, revealed differences in the executive function tests, and particularly in the WCST (p ≤ 0.001) and trail-making-test (TMT A/B) (p = 0.002). Conclusions: These differences suggest that the neuropsychological profile of poor-insight patients is different from their good-insight counterparts, emphasize the role played by the executive functions in insight and highlights the need for more accurate neurocognitive research and treatment.The second author wishes to acknowledge the support of the Foundation for Science and Technology (FCT), through IDMEC, under LAETA, project UIDB/50022/2020.Springer NatureRepositório da Universidade de LisboaManarte, LucasAndrade, António R.Rosário, Linete doSampaio, DanielFigueira, Maria LuísaMorgado, PedroSahakian, Barbara J.2021-05-19T14:32:53Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/48013engBMC Psychiatry. 2021 Apr 29;21(1):21610.1186/s12888-021-03227-w1471-244Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:51:11Zoai:repositorio.ul.pt:10451/48013Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:59:56.497133Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Executive functions and insight in OCD : a comparative study
title Executive functions and insight in OCD : a comparative study
spellingShingle Executive functions and insight in OCD : a comparative study
Manarte, Lucas
Executive functions
Insight
Obsessive-compulsive disorder
Trail-making test
Verbal memory
Wisconsin card sorting Test
title_short Executive functions and insight in OCD : a comparative study
title_full Executive functions and insight in OCD : a comparative study
title_fullStr Executive functions and insight in OCD : a comparative study
title_full_unstemmed Executive functions and insight in OCD : a comparative study
title_sort Executive functions and insight in OCD : a comparative study
author Manarte, Lucas
author_facet Manarte, Lucas
Andrade, António R.
Rosário, Linete do
Sampaio, Daniel
Figueira, Maria Luísa
Morgado, Pedro
Sahakian, Barbara J.
author_role author
author2 Andrade, António R.
Rosário, Linete do
Sampaio, Daniel
Figueira, Maria Luísa
Morgado, Pedro
Sahakian, Barbara J.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Manarte, Lucas
Andrade, António R.
Rosário, Linete do
Sampaio, Daniel
Figueira, Maria Luísa
Morgado, Pedro
Sahakian, Barbara J.
dc.subject.por.fl_str_mv Executive functions
Insight
Obsessive-compulsive disorder
Trail-making test
Verbal memory
Wisconsin card sorting Test
topic Executive functions
Insight
Obsessive-compulsive disorder
Trail-making test
Verbal memory
Wisconsin card sorting Test
description © The Author(s). 2021. This article is licensed under a Creative Commons Attribution 4.0 International License.
publishDate 2021
dc.date.none.fl_str_mv 2021-05-19T14:32:53Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/48013
url http://hdl.handle.net/10451/48013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv BMC Psychiatry. 2021 Apr 29;21(1):216
10.1186/s12888-021-03227-w
1471-244X
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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