Apert syndrome and repercussions in Dental Medicine
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10284/8582 |
Resumo: | Apert’s syndrome is a craniosynostosis syndrome caused by mutations in the gene coding for the fibroblast growthfactor receptor 2 (FGFR2), characterized by craniosynostosis, midface hypoplasia and syndactyly of the hands and feet. It has several oral manifestations, such as ogival palate, maxillary transverse and sagittal hypoplasia, dental crowding, eruptive delay and ectopic position of the teeth. The diagnosis of Apert’s syndrome is established in a proband with classic clinical characteristics, and genetic tests can also be performed. Patients with this syndrome often require craniofacial team care and dental, orthodontic and orthognathic surgical management because of their esthetic and functional problems such as Class III malocclusion and midface hypoplasia. The aim of this study is to present a literature review on oral manifestations of Apert’s syndrome and their impact on dental medicine. |
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Apert syndrome and repercussions in Dental MedicineApert syndromeCraniosynostosisOral abnormalitiesApert’s syndrome is a craniosynostosis syndrome caused by mutations in the gene coding for the fibroblast growthfactor receptor 2 (FGFR2), characterized by craniosynostosis, midface hypoplasia and syndactyly of the hands and feet. It has several oral manifestations, such as ogival palate, maxillary transverse and sagittal hypoplasia, dental crowding, eruptive delay and ectopic position of the teeth. The diagnosis of Apert’s syndrome is established in a proband with classic clinical characteristics, and genetic tests can also be performed. Patients with this syndrome often require craniofacial team care and dental, orthodontic and orthognathic surgical management because of their esthetic and functional problems such as Class III malocclusion and midface hypoplasia. The aim of this study is to present a literature review on oral manifestations of Apert’s syndrome and their impact on dental medicine.Repositório Institucional da Universidade Fernando PessoaPaula, Lígia deCardoso, Inês Lopes2020-03-02T10:42:12Z2020-02-28T15:54:58Z2020-01-10T00:00:00Z2020-01-10T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10284/8582engcv-prod-878045info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-06T02:07:57Zoai:bdigital.ufp.pt:10284/8582Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:45:27.751148Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Apert syndrome and repercussions in Dental Medicine |
title |
Apert syndrome and repercussions in Dental Medicine |
spellingShingle |
Apert syndrome and repercussions in Dental Medicine Paula, Lígia de Apert syndrome Craniosynostosis Oral abnormalities |
title_short |
Apert syndrome and repercussions in Dental Medicine |
title_full |
Apert syndrome and repercussions in Dental Medicine |
title_fullStr |
Apert syndrome and repercussions in Dental Medicine |
title_full_unstemmed |
Apert syndrome and repercussions in Dental Medicine |
title_sort |
Apert syndrome and repercussions in Dental Medicine |
author |
Paula, Lígia de |
author_facet |
Paula, Lígia de Cardoso, Inês Lopes |
author_role |
author |
author2 |
Cardoso, Inês Lopes |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Repositório Institucional da Universidade Fernando Pessoa |
dc.contributor.author.fl_str_mv |
Paula, Lígia de Cardoso, Inês Lopes |
dc.subject.por.fl_str_mv |
Apert syndrome Craniosynostosis Oral abnormalities |
topic |
Apert syndrome Craniosynostosis Oral abnormalities |
description |
Apert’s syndrome is a craniosynostosis syndrome caused by mutations in the gene coding for the fibroblast growthfactor receptor 2 (FGFR2), characterized by craniosynostosis, midface hypoplasia and syndactyly of the hands and feet. It has several oral manifestations, such as ogival palate, maxillary transverse and sagittal hypoplasia, dental crowding, eruptive delay and ectopic position of the teeth. The diagnosis of Apert’s syndrome is established in a proband with classic clinical characteristics, and genetic tests can also be performed. Patients with this syndrome often require craniofacial team care and dental, orthodontic and orthognathic surgical management because of their esthetic and functional problems such as Class III malocclusion and midface hypoplasia. The aim of this study is to present a literature review on oral manifestations of Apert’s syndrome and their impact on dental medicine. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-03-02T10:42:12Z 2020-02-28T15:54:58Z 2020-01-10T00:00:00Z 2020-01-10T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10284/8582 |
url |
http://hdl.handle.net/10284/8582 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
cv-prod-878045 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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