Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group

Detalhes bibliográficos
Autor(a) principal: Chevalley, Thierry
Data de Publicação: 2022
Outros Autores: Brandi, Maria Luisa, Cashman, Kevin D., Cavalier, Etienne, Harvey, Nicholas C., Maggi, Stefania, Cooper, Cyrus, Al-Daghri, Nasser, Bock, Oliver, Bruyère, Olivier, Rosa, Mário Miguel, Cortet, Bernard, Cruz-Jentoft, Alfonso J., Cherubini, Antonio, Dawson-Hughes, Bess, Fielding, Roger, Fuggle, Nicholas, Halbout, Philippe, Kanis, John A., Kaufman, Jean-Marc, Lamy, Olivier, Laslop, Andrea, Yerro, Maria Concepción Prieto, Radermecker, Régis, Thiyagarajan, Jotheeswaran Amuthavalli, Thomas, Thierry, Veronese, Nicola, de Wit, Marten, Reginster, Jean-Yves, Rizzoli, René
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/57228
Resumo: © The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
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spelling Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working groupFallsFragility fractureOsteoarthritisVitamin D© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Vitamin D is a key component for optimal growth and for calcium-phosphate homeostasis. Skin photosynthesis is the main source of vitamin D. Limited sun exposure and insufficient dietary vitamin D supply justify vitamin D supplementation in certain age groups. In older adults, recommended doses for vitamin D supplementation vary between 200 and 2000 IU/day, to achieve a goal of circulating 25-hydroxyvitamin D (calcifediol) of at least 50 nmol/L. The target level depends on the population being supplemented, the assessed system, and the outcome. Several recent large randomized trials with oral vitamin D regimens varying between 2000 and 100,000 IU/month and mostly conducted in vitamin D-replete and healthy individuals have failed to detect any efficacy of these approaches for the prevention of fracture and falls. Considering the well-recognized major musculoskeletal disorders associated with severe vitamin D deficiency and taking into account a possible biphasic effects of vitamin D on fracture and fall risks, an European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group convened, carefully reviewed, and analyzed the meta-analyses of randomized controlled trials on the effects of vitamin D on fracture risk, falls or osteoarthritis, and came to the conclusion that 1000 IU daily should be recommended in patients at increased risk of vitamin D deficiency. The group also addressed the identification of patients possibly benefitting from a vitamin D loading dose to achieve early 25-hydroxyvitamin D therapeutic level or from calcifediol administration.Open access funding provided by University of GenevaSpringer NatureRepositório da Universidade de LisboaChevalley, ThierryBrandi, Maria LuisaCashman, Kevin D.Cavalier, EtienneHarvey, Nicholas C.Maggi, StefaniaCooper, CyrusAl-Daghri, NasserBock, OliverBruyère, OlivierRosa, Mário MiguelCortet, BernardCruz-Jentoft, Alfonso J.Cherubini, AntonioDawson-Hughes, BessFielding, RogerFuggle, NicholasHalbout, PhilippeKanis, John A.Kaufman, Jean-MarcLamy, OlivierLaslop, AndreaYerro, Maria Concepción PrietoRadermecker, RégisThiyagarajan, Jotheeswaran AmuthavalliThomas, ThierryVeronese, Nicolade Wit, MartenReginster, Jean-YvesRizzoli, René2023-04-21T14:07:24Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/57228engAging Clin Exp Res. 2022 Nov;34(11):2603-26231594-066710.1007/s40520-022-02279-61720-8319info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:05:19Zoai:repositorio.ul.pt:10451/57228Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:07:39.477934Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
title Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
spellingShingle Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
Chevalley, Thierry
Falls
Fragility fracture
Osteoarthritis
Vitamin D
title_short Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
title_full Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
title_fullStr Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
title_full_unstemmed Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
title_sort Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
author Chevalley, Thierry
author_facet Chevalley, Thierry
Brandi, Maria Luisa
Cashman, Kevin D.
Cavalier, Etienne
Harvey, Nicholas C.
Maggi, Stefania
Cooper, Cyrus
Al-Daghri, Nasser
Bock, Oliver
Bruyère, Olivier
Rosa, Mário Miguel
Cortet, Bernard
Cruz-Jentoft, Alfonso J.
Cherubini, Antonio
Dawson-Hughes, Bess
Fielding, Roger
Fuggle, Nicholas
Halbout, Philippe
Kanis, John A.
Kaufman, Jean-Marc
Lamy, Olivier
Laslop, Andrea
Yerro, Maria Concepción Prieto
Radermecker, Régis
Thiyagarajan, Jotheeswaran Amuthavalli
Thomas, Thierry
Veronese, Nicola
de Wit, Marten
Reginster, Jean-Yves
Rizzoli, René
author_role author
author2 Brandi, Maria Luisa
Cashman, Kevin D.
Cavalier, Etienne
Harvey, Nicholas C.
Maggi, Stefania
Cooper, Cyrus
Al-Daghri, Nasser
Bock, Oliver
Bruyère, Olivier
Rosa, Mário Miguel
Cortet, Bernard
Cruz-Jentoft, Alfonso J.
Cherubini, Antonio
Dawson-Hughes, Bess
Fielding, Roger
Fuggle, Nicholas
Halbout, Philippe
Kanis, John A.
Kaufman, Jean-Marc
Lamy, Olivier
Laslop, Andrea
Yerro, Maria Concepción Prieto
Radermecker, Régis
Thiyagarajan, Jotheeswaran Amuthavalli
Thomas, Thierry
Veronese, Nicola
de Wit, Marten
Reginster, Jean-Yves
Rizzoli, René
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Chevalley, Thierry
Brandi, Maria Luisa
Cashman, Kevin D.
Cavalier, Etienne
Harvey, Nicholas C.
Maggi, Stefania
Cooper, Cyrus
Al-Daghri, Nasser
Bock, Oliver
Bruyère, Olivier
Rosa, Mário Miguel
Cortet, Bernard
Cruz-Jentoft, Alfonso J.
Cherubini, Antonio
Dawson-Hughes, Bess
Fielding, Roger
Fuggle, Nicholas
Halbout, Philippe
Kanis, John A.
Kaufman, Jean-Marc
Lamy, Olivier
Laslop, Andrea
Yerro, Maria Concepción Prieto
Radermecker, Régis
Thiyagarajan, Jotheeswaran Amuthavalli
Thomas, Thierry
Veronese, Nicola
de Wit, Marten
Reginster, Jean-Yves
Rizzoli, René
dc.subject.por.fl_str_mv Falls
Fragility fracture
Osteoarthritis
Vitamin D
topic Falls
Fragility fracture
Osteoarthritis
Vitamin D
description © The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-01-01T00:00:00Z
2023-04-21T14:07:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/57228
url http://hdl.handle.net/10451/57228
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Aging Clin Exp Res. 2022 Nov;34(11):2603-2623
1594-0667
10.1007/s40520-022-02279-6
1720-8319
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dc.publisher.none.fl_str_mv Springer Nature
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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