A Difficult Diagnosis of Plasmodium ovale Malaria

Detalhes bibliográficos
Autor(a) principal: Santos-Reis, Ana
Data de Publicação: 2022
Outros Autores: Nina, Jaime
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814
Resumo: Malaria is a major cause of suffering, disease, and death worldwide and is considered the most important of all human parasitic diseases. Malaria is still endemic in most tropical and sub-tropical areas and globalization has contributed to an increase of imported cases around the world. We report a Plasmodium ovale infection in a traveler with recent return from a long land trip across West Africa. He declared adherence to mefloquine chemoprophylaxis only at the start of the trip. Initially, he was seen at two different hospitals and in both he was screened for malaria by microscopy and rapid diagnostic test, but his diagnosis was not confirmed. The traveler was then diagnosed at our hospital with a malaria infection by Plasmodium ovale. Complete blood count showed mild anemia, but leukocytes and platelets were already normal. Symptoms resolved in 24 hours after treatment started. Microscopy of stained blood films remains the gold standard for malaria diagnosis, which is critically dependent on trained eyes. In non-endemic regions with few cases during the year, training programs in malaria microscopy are crucial. The aim is to prevent the reintroduction of malaria in Europe, reduce individual morbidity and suffering, and thus contribute towards reduction in deaths caused by this disease.
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spelling A Difficult Diagnosis of Plasmodium ovale MalariaUm Diagnóstico Difícil de Malária por Plasmodium ovaleEuropeMalaria/diagnosisMalaria/therapyPlasmodium ovalePortugalTravelEuropaMalaria/diagnósticoMalaria/tratamentoPlasmodium ovalePortugalViagemMalaria is a major cause of suffering, disease, and death worldwide and is considered the most important of all human parasitic diseases. Malaria is still endemic in most tropical and sub-tropical areas and globalization has contributed to an increase of imported cases around the world. We report a Plasmodium ovale infection in a traveler with recent return from a long land trip across West Africa. He declared adherence to mefloquine chemoprophylaxis only at the start of the trip. Initially, he was seen at two different hospitals and in both he was screened for malaria by microscopy and rapid diagnostic test, but his diagnosis was not confirmed. The traveler was then diagnosed at our hospital with a malaria infection by Plasmodium ovale. Complete blood count showed mild anemia, but leukocytes and platelets were already normal. Symptoms resolved in 24 hours after treatment started. Microscopy of stained blood films remains the gold standard for malaria diagnosis, which is critically dependent on trained eyes. In non-endemic regions with few cases during the year, training programs in malaria microscopy are crucial. The aim is to prevent the reintroduction of malaria in Europe, reduce individual morbidity and suffering, and thus contribute towards reduction in deaths caused by this disease.A malária é uma das principais causas de sofrimento, doença e morte no mundo e é considerada a mais importante doença parasitária em humanos. A malária ainda é endémica na maioria das áreas tropicais e sub-tropicais e a globalização tem contribuído para o aumento de casos em todo o mundo. Relatamos um caso de infeção por Plasmodium ovale num viajante com regresso recente de uma viagem por terra por vários países de África Ocidental. O viajante aderiu à profilaxia com mefloquina apenas no início da viagem. Já em Portugal, sentindo-se doente, febril, dirigiu-se a dois hospitais, onde realizou despiste para malária por microscopia e teste rápido, que foram descritos como negativos. Posteriormente, o viajante dirigiu-se ao nosso serviço onde foi diagnosticada uma infeção de malária por Plasmodium ovale. Os achados analíticos revelaram uma contagem de leucócitos normal, anemia moderada e, uma contagem de plaquetas já normal. Os sintomas terminaram com apenas 24 horas de tratamento. O método de referência do diagnóstico de malária continua a ser a microscopia, que é altamente dependente da experiência do pessoal do laboratório. Em regiões não endémicas com poucos casos durante o ano, é essencial promover e manter programas de capacitação em microscopia para prevenir a reintrodução da malária na Europa, diminuir a morbilidade e o sofrimento, e contribuir assim, para a redução do número de mortes pela doença.Ordem dos Médicos2022-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814oai:ojs.www.actamedicaportuguesa.com:article/15814Acta Médica Portuguesa; Vol. 35 No. 6 (2022): June; 484-487Acta Médica Portuguesa; Vol. 35 N.º 6 (2022): Junho; 484-4871646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814/6350Direitos de Autor (c) 2021 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessSantos-Reis, AnaNina, Jaime2022-12-20T11:07:38Zoai:ojs.www.actamedicaportuguesa.com:article/15814Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:41.014819Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A Difficult Diagnosis of Plasmodium ovale Malaria
Um Diagnóstico Difícil de Malária por Plasmodium ovale
title A Difficult Diagnosis of Plasmodium ovale Malaria
spellingShingle A Difficult Diagnosis of Plasmodium ovale Malaria
Santos-Reis, Ana
Europe
Malaria/diagnosis
Malaria/therapy
Plasmodium ovale
Portugal
Travel
Europa
Malaria/diagnóstico
Malaria/tratamento
Plasmodium ovale
Portugal
Viagem
title_short A Difficult Diagnosis of Plasmodium ovale Malaria
title_full A Difficult Diagnosis of Plasmodium ovale Malaria
title_fullStr A Difficult Diagnosis of Plasmodium ovale Malaria
title_full_unstemmed A Difficult Diagnosis of Plasmodium ovale Malaria
title_sort A Difficult Diagnosis of Plasmodium ovale Malaria
author Santos-Reis, Ana
author_facet Santos-Reis, Ana
Nina, Jaime
author_role author
author2 Nina, Jaime
author2_role author
dc.contributor.author.fl_str_mv Santos-Reis, Ana
Nina, Jaime
dc.subject.por.fl_str_mv Europe
Malaria/diagnosis
Malaria/therapy
Plasmodium ovale
Portugal
Travel
Europa
Malaria/diagnóstico
Malaria/tratamento
Plasmodium ovale
Portugal
Viagem
topic Europe
Malaria/diagnosis
Malaria/therapy
Plasmodium ovale
Portugal
Travel
Europa
Malaria/diagnóstico
Malaria/tratamento
Plasmodium ovale
Portugal
Viagem
description Malaria is a major cause of suffering, disease, and death worldwide and is considered the most important of all human parasitic diseases. Malaria is still endemic in most tropical and sub-tropical areas and globalization has contributed to an increase of imported cases around the world. We report a Plasmodium ovale infection in a traveler with recent return from a long land trip across West Africa. He declared adherence to mefloquine chemoprophylaxis only at the start of the trip. Initially, he was seen at two different hospitals and in both he was screened for malaria by microscopy and rapid diagnostic test, but his diagnosis was not confirmed. The traveler was then diagnosed at our hospital with a malaria infection by Plasmodium ovale. Complete blood count showed mild anemia, but leukocytes and platelets were already normal. Symptoms resolved in 24 hours after treatment started. Microscopy of stained blood films remains the gold standard for malaria diagnosis, which is critically dependent on trained eyes. In non-endemic regions with few cases during the year, training programs in malaria microscopy are crucial. The aim is to prevent the reintroduction of malaria in Europe, reduce individual morbidity and suffering, and thus contribute towards reduction in deaths caused by this disease.
publishDate 2022
dc.date.none.fl_str_mv 2022-06-01
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814
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dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814/6350
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2021 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2021 Acta Médica Portuguesa
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 35 No. 6 (2022): June; 484-487
Acta Médica Portuguesa; Vol. 35 N.º 6 (2022): Junho; 484-487
1646-0758
0870-399X
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