A Difficult Diagnosis of Plasmodium ovale Malaria
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814 |
Resumo: | Malaria is a major cause of suffering, disease, and death worldwide and is considered the most important of all human parasitic diseases. Malaria is still endemic in most tropical and sub-tropical areas and globalization has contributed to an increase of imported cases around the world. We report a Plasmodium ovale infection in a traveler with recent return from a long land trip across West Africa. He declared adherence to mefloquine chemoprophylaxis only at the start of the trip. Initially, he was seen at two different hospitals and in both he was screened for malaria by microscopy and rapid diagnostic test, but his diagnosis was not confirmed. The traveler was then diagnosed at our hospital with a malaria infection by Plasmodium ovale. Complete blood count showed mild anemia, but leukocytes and platelets were already normal. Symptoms resolved in 24 hours after treatment started. Microscopy of stained blood films remains the gold standard for malaria diagnosis, which is critically dependent on trained eyes. In non-endemic regions with few cases during the year, training programs in malaria microscopy are crucial. The aim is to prevent the reintroduction of malaria in Europe, reduce individual morbidity and suffering, and thus contribute towards reduction in deaths caused by this disease. |
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A Difficult Diagnosis of Plasmodium ovale MalariaUm Diagnóstico Difícil de Malária por Plasmodium ovaleEuropeMalaria/diagnosisMalaria/therapyPlasmodium ovalePortugalTravelEuropaMalaria/diagnósticoMalaria/tratamentoPlasmodium ovalePortugalViagemMalaria is a major cause of suffering, disease, and death worldwide and is considered the most important of all human parasitic diseases. Malaria is still endemic in most tropical and sub-tropical areas and globalization has contributed to an increase of imported cases around the world. We report a Plasmodium ovale infection in a traveler with recent return from a long land trip across West Africa. He declared adherence to mefloquine chemoprophylaxis only at the start of the trip. Initially, he was seen at two different hospitals and in both he was screened for malaria by microscopy and rapid diagnostic test, but his diagnosis was not confirmed. The traveler was then diagnosed at our hospital with a malaria infection by Plasmodium ovale. Complete blood count showed mild anemia, but leukocytes and platelets were already normal. Symptoms resolved in 24 hours after treatment started. Microscopy of stained blood films remains the gold standard for malaria diagnosis, which is critically dependent on trained eyes. In non-endemic regions with few cases during the year, training programs in malaria microscopy are crucial. The aim is to prevent the reintroduction of malaria in Europe, reduce individual morbidity and suffering, and thus contribute towards reduction in deaths caused by this disease.A malária é uma das principais causas de sofrimento, doença e morte no mundo e é considerada a mais importante doença parasitária em humanos. A malária ainda é endémica na maioria das áreas tropicais e sub-tropicais e a globalização tem contribuído para o aumento de casos em todo o mundo. Relatamos um caso de infeção por Plasmodium ovale num viajante com regresso recente de uma viagem por terra por vários países de África Ocidental. O viajante aderiu à profilaxia com mefloquina apenas no início da viagem. Já em Portugal, sentindo-se doente, febril, dirigiu-se a dois hospitais, onde realizou despiste para malária por microscopia e teste rápido, que foram descritos como negativos. Posteriormente, o viajante dirigiu-se ao nosso serviço onde foi diagnosticada uma infeção de malária por Plasmodium ovale. Os achados analíticos revelaram uma contagem de leucócitos normal, anemia moderada e, uma contagem de plaquetas já normal. Os sintomas terminaram com apenas 24 horas de tratamento. O método de referência do diagnóstico de malária continua a ser a microscopia, que é altamente dependente da experiência do pessoal do laboratório. Em regiões não endémicas com poucos casos durante o ano, é essencial promover e manter programas de capacitação em microscopia para prevenir a reintrodução da malária na Europa, diminuir a morbilidade e o sofrimento, e contribuir assim, para a redução do número de mortes pela doença.Ordem dos Médicos2022-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814oai:ojs.www.actamedicaportuguesa.com:article/15814Acta Médica Portuguesa; Vol. 35 No. 6 (2022): June; 484-487Acta Médica Portuguesa; Vol. 35 N.º 6 (2022): Junho; 484-4871646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814/6350Direitos de Autor (c) 2021 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessSantos-Reis, AnaNina, Jaime2022-12-20T11:07:38Zoai:ojs.www.actamedicaportuguesa.com:article/15814Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:41.014819Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A Difficult Diagnosis of Plasmodium ovale Malaria Um Diagnóstico Difícil de Malária por Plasmodium ovale |
title |
A Difficult Diagnosis of Plasmodium ovale Malaria |
spellingShingle |
A Difficult Diagnosis of Plasmodium ovale Malaria Santos-Reis, Ana Europe Malaria/diagnosis Malaria/therapy Plasmodium ovale Portugal Travel Europa Malaria/diagnóstico Malaria/tratamento Plasmodium ovale Portugal Viagem |
title_short |
A Difficult Diagnosis of Plasmodium ovale Malaria |
title_full |
A Difficult Diagnosis of Plasmodium ovale Malaria |
title_fullStr |
A Difficult Diagnosis of Plasmodium ovale Malaria |
title_full_unstemmed |
A Difficult Diagnosis of Plasmodium ovale Malaria |
title_sort |
A Difficult Diagnosis of Plasmodium ovale Malaria |
author |
Santos-Reis, Ana |
author_facet |
Santos-Reis, Ana Nina, Jaime |
author_role |
author |
author2 |
Nina, Jaime |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Santos-Reis, Ana Nina, Jaime |
dc.subject.por.fl_str_mv |
Europe Malaria/diagnosis Malaria/therapy Plasmodium ovale Portugal Travel Europa Malaria/diagnóstico Malaria/tratamento Plasmodium ovale Portugal Viagem |
topic |
Europe Malaria/diagnosis Malaria/therapy Plasmodium ovale Portugal Travel Europa Malaria/diagnóstico Malaria/tratamento Plasmodium ovale Portugal Viagem |
description |
Malaria is a major cause of suffering, disease, and death worldwide and is considered the most important of all human parasitic diseases. Malaria is still endemic in most tropical and sub-tropical areas and globalization has contributed to an increase of imported cases around the world. We report a Plasmodium ovale infection in a traveler with recent return from a long land trip across West Africa. He declared adherence to mefloquine chemoprophylaxis only at the start of the trip. Initially, he was seen at two different hospitals and in both he was screened for malaria by microscopy and rapid diagnostic test, but his diagnosis was not confirmed. The traveler was then diagnosed at our hospital with a malaria infection by Plasmodium ovale. Complete blood count showed mild anemia, but leukocytes and platelets were already normal. Symptoms resolved in 24 hours after treatment started. Microscopy of stained blood films remains the gold standard for malaria diagnosis, which is critically dependent on trained eyes. In non-endemic regions with few cases during the year, training programs in malaria microscopy are crucial. The aim is to prevent the reintroduction of malaria in Europe, reduce individual morbidity and suffering, and thus contribute towards reduction in deaths caused by this disease. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-06-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814 oai:ojs.www.actamedicaportuguesa.com:article/15814 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/15814 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15814/6350 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2021 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
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Direitos de Autor (c) 2021 Acta Médica Portuguesa |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 35 No. 6 (2022): June; 484-487 Acta Médica Portuguesa; Vol. 35 N.º 6 (2022): Junho; 484-487 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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