Cation-mediated gelation of the fucose-rich polysaccharide FucoPol
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/93177 |
Resumo: | FCT/MEC (UID/Multi/04378/2019). PEst-OE/AGR/UI0245/2014. POCI-01-0145-FEDER-007728 and POCI-01-0145-FEDER - 007265. SFRH/BD/140829/2018. SFRH/BPD/124612/2016. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Cation-mediated gelation of the fucose-rich polysaccharide FucoPolpreparation and characterization of hydrogel beads and their cytotoxicity assessmentcytotoxicityFucoPolhydrogel beadsAnalytical ChemistryChemical Engineering(all)Polymers and PlasticsFCT/MEC (UID/Multi/04378/2019). PEst-OE/AGR/UI0245/2014. POCI-01-0145-FEDER-007728 and POCI-01-0145-FEDER - 007265. SFRH/BD/140829/2018. SFRH/BPD/124612/2016.This study describes for the first time the iron- and copper-mediated gelation of FucoPol, fucose-rich bacterial polysaccharide. The ability of FucoPol to gel in the presence of metal cations, including iron(III) and copper(II), was used for the preparation of hydrogel beads. Iron mediated the formation of stable and not cytotoxic gel beads, while copper resulted in fragile and cytotoxic ones. Copper-mediated beads coated with an iron-mediated gel layer were more stable and had reduced cytotoxicity. The resulting polymeric structures had differing morphology, physical properties and cytotoxicity, which support their use in several applications, including biomedicine, agriculture and bioremediation.UCIBIO - Applied Molecular Biosciences UnitDQ - Departamento de QuímicaDCV - Departamento de Ciências da VidaRUNFialho, LetíciaAraújo, DianaAlves, Vitor D.Roma-Rodrigues, CatarinaBaptista, Pedro V.Fernandes, Alexandra R.Freitas, FilomenaReis, Maria A. M.2022-10-24T00:32:48Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/93177eng0091-4037PURE: 15668277https://doi.org/10.1080/00914037.2019.1695205info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-22T17:43:39Zoai:run.unl.pt:10362/93177Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-22T17:43:39Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Cation-mediated gelation of the fucose-rich polysaccharide FucoPol preparation and characterization of hydrogel beads and their cytotoxicity assessment |
title |
Cation-mediated gelation of the fucose-rich polysaccharide FucoPol |
spellingShingle |
Cation-mediated gelation of the fucose-rich polysaccharide FucoPol Fialho, Letícia cytotoxicity FucoPol hydrogel beads Analytical Chemistry Chemical Engineering(all) Polymers and Plastics |
title_short |
Cation-mediated gelation of the fucose-rich polysaccharide FucoPol |
title_full |
Cation-mediated gelation of the fucose-rich polysaccharide FucoPol |
title_fullStr |
Cation-mediated gelation of the fucose-rich polysaccharide FucoPol |
title_full_unstemmed |
Cation-mediated gelation of the fucose-rich polysaccharide FucoPol |
title_sort |
Cation-mediated gelation of the fucose-rich polysaccharide FucoPol |
author |
Fialho, Letícia |
author_facet |
Fialho, Letícia Araújo, Diana Alves, Vitor D. Roma-Rodrigues, Catarina Baptista, Pedro V. Fernandes, Alexandra R. Freitas, Filomena Reis, Maria A. M. |
author_role |
author |
author2 |
Araújo, Diana Alves, Vitor D. Roma-Rodrigues, Catarina Baptista, Pedro V. Fernandes, Alexandra R. Freitas, Filomena Reis, Maria A. M. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
UCIBIO - Applied Molecular Biosciences Unit DQ - Departamento de Química DCV - Departamento de Ciências da Vida RUN |
dc.contributor.author.fl_str_mv |
Fialho, Letícia Araújo, Diana Alves, Vitor D. Roma-Rodrigues, Catarina Baptista, Pedro V. Fernandes, Alexandra R. Freitas, Filomena Reis, Maria A. M. |
dc.subject.por.fl_str_mv |
cytotoxicity FucoPol hydrogel beads Analytical Chemistry Chemical Engineering(all) Polymers and Plastics |
topic |
cytotoxicity FucoPol hydrogel beads Analytical Chemistry Chemical Engineering(all) Polymers and Plastics |
description |
FCT/MEC (UID/Multi/04378/2019). PEst-OE/AGR/UI0245/2014. POCI-01-0145-FEDER-007728 and POCI-01-0145-FEDER - 007265. SFRH/BD/140829/2018. SFRH/BPD/124612/2016. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021 2021-01-01T00:00:00Z 2022-10-24T00:32:48Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/93177 |
url |
http://hdl.handle.net/10362/93177 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0091-4037 PURE: 15668277 https://doi.org/10.1080/00914037.2019.1695205 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
_version_ |
1817545727826460672 |