Effect of caffeine and cognitive tests on cerebral hemodynamic in young students from the Dr. Lopes Dias Superior Health School

• Autor(a) principal: Pires, Marizete
• Data de Publicação: 2022
• Outros Autores: Nunes, Gil, Rodrigues, Francisco, Coelho, Patrícia, Pires, Joana
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://doi.org/10.25758/set.489
• topic: Cafeína; Triplex scan transcraniano; Testes cognitivos; Artérias cerebrais; Caffeine; Transcranial color-coded duplex sonography; Cerebral arteries; Cognitive tests

Introduction – Caffeine induces physiological changes, such as increased blood pressure, which is reflected in cerebral hemodynamics. Objectives – Evaluate the effect of caffeine on changes in the flow of the cerebral arteries studied, as well as relate their effect with cognitive tests. Methods – Observational, prospective study in 35 students, aged between 18 and 25, at Escola Superior de Saude Dr. Lopes Dias. The volunteers were divided into two groups, with group 1 having a normal coffee and group 2 being a white brand decaffeinated, without added sugar. The procedure was divided into two phases, pre- and post-stimulant. Data were collected through the transcranial color-coded duplex sonography and the MoCa cognitive test, after free and informed consent. On the course of study was assured the principles of the Declaration of Helsinki. The following non-parametric tests were used to correlate the variables: Wilcoxon, Spearman, and Mann-Whitney. Results – Compared to baseline, in the caffeine condition there was an increase in flow variations in the middle cerebral arteries (p=0.0001), the same happened with the MoCa Test score (p=0.0001). Discussion – In the analysis of the flow of the main cerebral arteries and when performing cognitive tests, there is a significant increase in the flow under the effect of the caffeine, although this is more noticeable in the middle cerebral artery. Conclusion – The middle cerebral artery is the artery most susceptible to modifications, however, these are independent of the beverage with caffeine used, the same happens when performing the MoCa Test.