The effect of platelet rich fibrin in oral surgery: a literature review

Detalhes bibliográficos
Autor(a) principal: Pedro, Beatriz Mancebo Vieira
Data de Publicação: 2017
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/29500
Resumo: Tese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2017
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spelling The effect of platelet rich fibrin in oral surgery: a literature reviewCirurgia oralTeses de mestrado - 2017Domínio/Área Científica::Ciências Médicas::Medicina ClínicaTese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2017To summarize the relevant literature regarding the clinical efficacy of Platelet Rich Fibrin (PRF) in oral surgery and its applications in clinical practice. Introduction: One of the challenges facing clinical research is the development of bioactive surgical additives regulating inflammation and increasing healing. Platelet Rich Fibrin is a second-generation platelet concentrate developed by Dr. Joseph Choukroun, in 2001. The combined properties of fibrin, platelets, leucocytes, growth factors and cytokines makes Platelet Rich Fibrin a healing biomaterial with tremendous potential for bone and soft tissue regeneration (Dohan, D., et al., 2006). Materials and Methods: The research was based on articles published from March 2006 until April 10th 2017 on the databases Cochrane Library and Medline (PubMed), with the combination of the key-words: Platelet Rich Fibrin, Platelet Concentrates, Oral Surgery, Healing and Tissue Regeneration. The included studies were: Meta-analysis, Systematic Reviews and Randomized Control Trials, which were extended afterwards to include Controlled Clinical Trials, Reviews, Cohorts, Case Reports and In vitro studies. Inclusion criteria consisted of articles published in the last 10 years and available in English. Articles were also retrieved after analyzing the reference list of articles previously obtained. Results: The search yielded 1455 articles, of which 86 were selected for inclusion, and 93 additional articles were obtained from the reference lists of other articles, making a total of 179 articles. Discussion and Conclusion: The scientific literature demonstrated safe and promising results related to the use of Platelet Rich Fibrin, defending that it has several advantages and possible indications to be used both in medicine and dentistry. Although many authors advocate positive results, further research with well-designed randomized controlled trials and with long-term follow-up, is necessary to clarify clinical outcomes.Caramês, João, 1962-Francisco, HelenaRepositório da Universidade de LisboaPedro, Beatriz Mancebo Vieira2017-10-31T13:16:23Z201720172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10451/29500TID:201737205enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:21:37Zoai:repositorio.ul.pt:10451/29500Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:45:22.732495Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The effect of platelet rich fibrin in oral surgery: a literature review
title The effect of platelet rich fibrin in oral surgery: a literature review
spellingShingle The effect of platelet rich fibrin in oral surgery: a literature review
Pedro, Beatriz Mancebo Vieira
Cirurgia oral
Teses de mestrado - 2017
Domínio/Área Científica::Ciências Médicas::Medicina Clínica
title_short The effect of platelet rich fibrin in oral surgery: a literature review
title_full The effect of platelet rich fibrin in oral surgery: a literature review
title_fullStr The effect of platelet rich fibrin in oral surgery: a literature review
title_full_unstemmed The effect of platelet rich fibrin in oral surgery: a literature review
title_sort The effect of platelet rich fibrin in oral surgery: a literature review
author Pedro, Beatriz Mancebo Vieira
author_facet Pedro, Beatriz Mancebo Vieira
author_role author
dc.contributor.none.fl_str_mv Caramês, João, 1962-
Francisco, Helena
Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Pedro, Beatriz Mancebo Vieira
dc.subject.por.fl_str_mv Cirurgia oral
Teses de mestrado - 2017
Domínio/Área Científica::Ciências Médicas::Medicina Clínica
topic Cirurgia oral
Teses de mestrado - 2017
Domínio/Área Científica::Ciências Médicas::Medicina Clínica
description Tese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2017
publishDate 2017
dc.date.none.fl_str_mv 2017-10-31T13:16:23Z
2017
2017
2017-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/29500
TID:201737205
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identifier_str_mv TID:201737205
dc.language.iso.fl_str_mv eng
language eng
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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