Thrombus aspiration in patients with ST-elevation myocardial infarction
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.1186/s12872-018-0794-4 |
Resumo: | Background: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. Methods: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). Conclusions: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI. |
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Thrombus aspiration in patients with ST-elevation myocardial infarctionResults of a national registry of interventional cardiologyAngioplastyMortalityPortugalPrimary PCIThrombectomyThrombus aspirationCardiology and Cardiovascular MedicineBackground: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. Methods: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). Conclusions: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNPereira, HélderCaldeira, DanielTeles, Rui CampanteCosta, Marcoda Silva, Pedro Canasda Gama Ribeiro, VascoBrandão, VítorMartins, DinisMatias, FernandoPereira-Machado, FranciscoBaptista, JoséAbreu, Pedro Farto e.Santos, RicardoDrummond, Antóniode Carvalho, Henrique CyrneCalisto, JoãoSilva, João CarlosPipa, João LuísMarques, JorgeSousa, PaulinoFernandes, RenatoFerreira, Rui CruzRamos, SousaOliveira, Eduardo Infantede Sousa Almeida, Manuel2019-02-26T23:14:04Z2018-04-242018-04-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.1186/s12872-018-0794-4eng1471-2261PURE: 11734698http://www.scopus.com/inward/record.url?scp=85046009523&partnerID=8YFLogxKhttps://doi.org/10.1186/s12872-018-0794-4info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:29:20Zoai:run.unl.pt:10362/61748Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:33:40.897307Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Thrombus aspiration in patients with ST-elevation myocardial infarction Results of a national registry of interventional cardiology |
title |
Thrombus aspiration in patients with ST-elevation myocardial infarction |
spellingShingle |
Thrombus aspiration in patients with ST-elevation myocardial infarction Pereira, Hélder Angioplasty Mortality Portugal Primary PCI Thrombectomy Thrombus aspiration Cardiology and Cardiovascular Medicine |
title_short |
Thrombus aspiration in patients with ST-elevation myocardial infarction |
title_full |
Thrombus aspiration in patients with ST-elevation myocardial infarction |
title_fullStr |
Thrombus aspiration in patients with ST-elevation myocardial infarction |
title_full_unstemmed |
Thrombus aspiration in patients with ST-elevation myocardial infarction |
title_sort |
Thrombus aspiration in patients with ST-elevation myocardial infarction |
author |
Pereira, Hélder |
author_facet |
Pereira, Hélder Caldeira, Daniel Teles, Rui Campante Costa, Marco da Silva, Pedro Canas da Gama Ribeiro, Vasco Brandão, Vítor Martins, Dinis Matias, Fernando Pereira-Machado, Francisco Baptista, José Abreu, Pedro Farto e. Santos, Ricardo Drummond, António de Carvalho, Henrique Cyrne Calisto, João Silva, João Carlos Pipa, João Luís Marques, Jorge Sousa, Paulino Fernandes, Renato Ferreira, Rui Cruz Ramos, Sousa Oliveira, Eduardo Infante de Sousa Almeida, Manuel |
author_role |
author |
author2 |
Caldeira, Daniel Teles, Rui Campante Costa, Marco da Silva, Pedro Canas da Gama Ribeiro, Vasco Brandão, Vítor Martins, Dinis Matias, Fernando Pereira-Machado, Francisco Baptista, José Abreu, Pedro Farto e. Santos, Ricardo Drummond, António de Carvalho, Henrique Cyrne Calisto, João Silva, João Carlos Pipa, João Luís Marques, Jorge Sousa, Paulino Fernandes, Renato Ferreira, Rui Cruz Ramos, Sousa Oliveira, Eduardo Infante de Sousa Almeida, Manuel |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
dc.contributor.author.fl_str_mv |
Pereira, Hélder Caldeira, Daniel Teles, Rui Campante Costa, Marco da Silva, Pedro Canas da Gama Ribeiro, Vasco Brandão, Vítor Martins, Dinis Matias, Fernando Pereira-Machado, Francisco Baptista, José Abreu, Pedro Farto e. Santos, Ricardo Drummond, António de Carvalho, Henrique Cyrne Calisto, João Silva, João Carlos Pipa, João Luís Marques, Jorge Sousa, Paulino Fernandes, Renato Ferreira, Rui Cruz Ramos, Sousa Oliveira, Eduardo Infante de Sousa Almeida, Manuel |
dc.subject.por.fl_str_mv |
Angioplasty Mortality Portugal Primary PCI Thrombectomy Thrombus aspiration Cardiology and Cardiovascular Medicine |
topic |
Angioplasty Mortality Portugal Primary PCI Thrombectomy Thrombus aspiration Cardiology and Cardiovascular Medicine |
description |
Background: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. Methods: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). Conclusions: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-04-24 2018-04-24T00:00:00Z 2019-02-26T23:14:04Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.1186/s12872-018-0794-4 |
url |
https://doi.org/10.1186/s12872-018-0794-4 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1471-2261 PURE: 11734698 http://www.scopus.com/inward/record.url?scp=85046009523&partnerID=8YFLogxK https://doi.org/10.1186/s12872-018-0794-4 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.source.none.fl_str_mv |
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