Poly(methylene blue) modified electrode sensor for haemoglobin

Detalhes bibliográficos
Autor(a) principal: Brett, Christopher M. A.
Data de Publicação: 1999
Outros Autores: Inzelt, György, Kertesz, Vilmos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/5267
https://doi.org/10.1016/S0003-2670(98)00808-3
Resumo: Poly(methylene blue) modified electrodes have been prepared by potential cycling from aqueous electrolyte solution containing methylene blue on glassy carbon substrates. They have been used successfully for the determination of haemoglobin via its electrooxidation at fixed potential using the batch injection analysis technique in which whole blood samples diluted with phosphate or acetate buffer are injected directly over the modified electrode immersed in inert electrolyte. Electrode response is fast, stable, and reproducible. For blood from healthy donors, a good linear correlation was found between the results from the electrochemical injection method and the conventional clinical spectrophotometric measurement after cyanidation. The blood from potentially ill donors showed deviations from the linear correlation suggesting that this may be a good method for detecting haematological problems.
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spelling Poly(methylene blue) modified electrode sensor for haemoglobinPoly(methylene blue)Modified electrodesHaemoglobinElectrochemical sensorBatch injection analysisPoly(methylene blue) modified electrodes have been prepared by potential cycling from aqueous electrolyte solution containing methylene blue on glassy carbon substrates. They have been used successfully for the determination of haemoglobin via its electrooxidation at fixed potential using the batch injection analysis technique in which whole blood samples diluted with phosphate or acetate buffer are injected directly over the modified electrode immersed in inert electrolyte. Electrode response is fast, stable, and reproducible. For blood from healthy donors, a good linear correlation was found between the results from the electrochemical injection method and the conventional clinical spectrophotometric measurement after cyanidation. The blood from potentially ill donors showed deviations from the linear correlation suggesting that this may be a good method for detecting haematological problems.http://www.sciencedirect.com/science/article/B6TF4-3W3N6Y2-F/1/af468a9610cd9500c6eb9e2e3c93f4341999info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/5267http://hdl.handle.net/10316/5267https://doi.org/10.1016/S0003-2670(98)00808-3engAnalytica Chimica Acta. 385:1-3 (1999) 119-123Brett, Christopher M. A.Inzelt, GyörgyKertesz, Vilmosinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-11-06T16:59:26Zoai:estudogeral.uc.pt:10316/5267Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:01:23.686690Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Poly(methylene blue) modified electrode sensor for haemoglobin
title Poly(methylene blue) modified electrode sensor for haemoglobin
spellingShingle Poly(methylene blue) modified electrode sensor for haemoglobin
Brett, Christopher M. A.
Poly(methylene blue)
Modified electrodes
Haemoglobin
Electrochemical sensor
Batch injection analysis
title_short Poly(methylene blue) modified electrode sensor for haemoglobin
title_full Poly(methylene blue) modified electrode sensor for haemoglobin
title_fullStr Poly(methylene blue) modified electrode sensor for haemoglobin
title_full_unstemmed Poly(methylene blue) modified electrode sensor for haemoglobin
title_sort Poly(methylene blue) modified electrode sensor for haemoglobin
author Brett, Christopher M. A.
author_facet Brett, Christopher M. A.
Inzelt, György
Kertesz, Vilmos
author_role author
author2 Inzelt, György
Kertesz, Vilmos
author2_role author
author
dc.contributor.author.fl_str_mv Brett, Christopher M. A.
Inzelt, György
Kertesz, Vilmos
dc.subject.por.fl_str_mv Poly(methylene blue)
Modified electrodes
Haemoglobin
Electrochemical sensor
Batch injection analysis
topic Poly(methylene blue)
Modified electrodes
Haemoglobin
Electrochemical sensor
Batch injection analysis
description Poly(methylene blue) modified electrodes have been prepared by potential cycling from aqueous electrolyte solution containing methylene blue on glassy carbon substrates. They have been used successfully for the determination of haemoglobin via its electrooxidation at fixed potential using the batch injection analysis technique in which whole blood samples diluted with phosphate or acetate buffer are injected directly over the modified electrode immersed in inert electrolyte. Electrode response is fast, stable, and reproducible. For blood from healthy donors, a good linear correlation was found between the results from the electrochemical injection method and the conventional clinical spectrophotometric measurement after cyanidation. The blood from potentially ill donors showed deviations from the linear correlation suggesting that this may be a good method for detecting haematological problems.
publishDate 1999
dc.date.none.fl_str_mv 1999
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/5267
http://hdl.handle.net/10316/5267
https://doi.org/10.1016/S0003-2670(98)00808-3
url http://hdl.handle.net/10316/5267
https://doi.org/10.1016/S0003-2670(98)00808-3
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Analytica Chimica Acta. 385:1-3 (1999) 119-123
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