Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquor
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/1822/42838 |
Resumo: | "Available online 15 October 2016" |
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Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquorFood wasteHyaluronic acidPolysaccharideSubmerged cultureStreptococcus zooepidemicusBiorefineryScience & Technology"Available online 15 October 2016"Agro-industrial by-products are being explored as alternative low-cost nutrients to produce hyaluronic acid (HA) by Streptococcus zooepidemicus. In this study, we formulated three culture media containing corn steep liquor (CSL) and sugarcane molasses (M), to produce microbial HA using batch bioreactor conditions (pH 6.7, 500 rpm and 1 vvm aeration). Final HA concentrations of 3.48 g L1 were produced in culture medium containing corn steep liquor (10% v/v) and glucose, being comparable (3.60 g L1) to the control medium containing tryptone and glucose. The use of molasses (10% v/v) as carbon source produced a marked inhibition of S. zooepidemicus growth and HA production due to a low sugar consumption. The HA produced in CSL culture media had a high molecular weight of 3.8 × 103 kDa, greater than HA produced in tryptone-containing medium (3.0 × 103 kDa). This is the first report achieving HA productions comparable to synthetic a medium in a batch bioreactor using CSL as the main nitrogen source. However, further optimization of culture conditions must be carried out towards using this agricultural by-product for the sustainable industrial production of HA.This research was financially supported by projects: MAT2010-21509-C03-01 (Ministerio de Economía y Competitividad, Spain) and FP7 Project BiValBi. Biotechnologies to Valorise the regional food Biodiversity in Latin America (PIRSES-GA-2013-611493)Elsevier B.V.Universidade do MinhoAmado, Isabel R.Vázquez, José A.Pastrana, LorenzoTeixeira, J. A.20172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/42838engAmado, I. R.; Vázquez, José A.; Pastrana, Lorenzo; Teixeira, J. A., Microbial production of hyaluronic acid from agro-industrial by-products: Molasses and corn steep liquor. Biochemical Engineering Journal, 117, Part A, 181-187, 20171369-703X1369-703X10.1016/j.bej.2016.09.017http://www.elsevier.com/locate/issn/1369703Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:17:54Zoai:repositorium.sdum.uminho.pt:1822/42838Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:10:36.443365Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquor |
| title |
Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquor |
| spellingShingle |
Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquor Amado, Isabel R. Food waste Hyaluronic acid Polysaccharide Submerged culture Streptococcus zooepidemicus Biorefinery Science & Technology |
| title_short |
Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquor |
| title_full |
Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquor |
| title_fullStr |
Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquor |
| title_full_unstemmed |
Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquor |
| title_sort |
Microbial production of hyaluronic acid from agro-industrial by-products: molasses and corn steep liquor |
| author |
Amado, Isabel R. |
| author_facet |
Amado, Isabel R. Vázquez, José A. Pastrana, Lorenzo Teixeira, J. A. |
| author_role |
author |
| author2 |
Vázquez, José A. Pastrana, Lorenzo Teixeira, J. A. |
| author2_role |
author author author |
| dc.contributor.none.fl_str_mv |
Universidade do Minho |
| dc.contributor.author.fl_str_mv |
Amado, Isabel R. Vázquez, José A. Pastrana, Lorenzo Teixeira, J. A. |
| dc.subject.por.fl_str_mv |
Food waste Hyaluronic acid Polysaccharide Submerged culture Streptococcus zooepidemicus Biorefinery Science & Technology |
| topic |
Food waste Hyaluronic acid Polysaccharide Submerged culture Streptococcus zooepidemicus Biorefinery Science & Technology |
| description |
"Available online 15 October 2016" |
| publishDate |
2017 |
| dc.date.none.fl_str_mv |
2017 2017-01-01T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/42838 |
| url |
http://hdl.handle.net/1822/42838 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Amado, I. R.; Vázquez, José A.; Pastrana, Lorenzo; Teixeira, J. A., Microbial production of hyaluronic acid from agro-industrial by-products: Molasses and corn steep liquor. Biochemical Engineering Journal, 117, Part A, 181-187, 2017 1369-703X 1369-703X 10.1016/j.bej.2016.09.017 http://www.elsevier.com/locate/issn/1369703X |
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info:eu-repo/semantics/openAccess |
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openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Elsevier B.V. |
| publisher.none.fl_str_mv |
Elsevier B.V. |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799132535942283264 |