Editorial: Disease-on-a-chip: from point-of-care to personalized medicine

• Autor(a) principal: Cruz, Andrea
• Data de Publicação: 2023
• Outros Autores: Fernandes, Elisabete, Rodrigues, Raquel Oliveira, Catarino, Susana Oliveira, Pinho, Diana
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://hdl.handle.net/1822/88653
• topic: Lab-on-chip; Microfluidic devices; Miniaturization; Organ-on-chip; Detection systems; Drug-device; Digital pills; Ciências Médicas::Biotecnologia Médica; Saúde de qualidade

[Excerpt] Introduction Miniaturization has played a pivotal role in driving innovation in microfluidic devices, particularly in their application across advanced technologies, such as Lab-on-chip platforms, Point-of-care systems, Organ-, Body- and Disease-on-a-chip technology. The personalized nature inherent in these systems, coupled with physiologically relevant readouts, opens novel avenues for individualized disease diagnostics, Figure 1. Additionally, they offer personalized strategies for assessing treatment efficacy and safety. Furthermore, the advancement in micro- and nano-microfluidic fabrication allows parallel analysis of large samples sets and the evaluation of different parameters such as biological molecules, cells or drugs.[...]