Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine

Detalhes bibliográficos
Autor(a) principal: Ladeira, Bruno M.
Data de Publicação: 2022
Outros Autores: Custódio, Catarina A., Mano, João F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10773/34428
Resumo: The fabrication of scaffolds that accurately recreate the architecture of living tissues is a major challenge in the field of tissue engineering and regenerative medicine. Core-shell microcapsules hold great potential in this regard, as they can recreate the hierarchical structure of biological systems. The independent modulation of the composition of both core and shell layers allows the design of compartmentalized platforms tailored to the recreation of specific cell niches. Emergent technologies such as superhydrophobic surfaces, microfluidics, electrospray, and layer-by-layer assembly have been successful in producing core-shell microcapsules for the encapsulation of cells and bioactive factors. This review provides an overview of available materials and techniques used in the generation of core-shell microcapsules, while also highlighting some of their potential applications in the design of innovative and effective tissue engineering and regenerative medicine strategies.
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spelling Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicineMicroencapsulationMicrocapsulesCore-shell structuresTissue EngineeringRegenerative medicineThe fabrication of scaffolds that accurately recreate the architecture of living tissues is a major challenge in the field of tissue engineering and regenerative medicine. Core-shell microcapsules hold great potential in this regard, as they can recreate the hierarchical structure of biological systems. The independent modulation of the composition of both core and shell layers allows the design of compartmentalized platforms tailored to the recreation of specific cell niches. Emergent technologies such as superhydrophobic surfaces, microfluidics, electrospray, and layer-by-layer assembly have been successful in producing core-shell microcapsules for the encapsulation of cells and bioactive factors. This review provides an overview of available materials and techniques used in the generation of core-shell microcapsules, while also highlighting some of their potential applications in the design of innovative and effective tissue engineering and regenerative medicine strategies.Royal Society of Chemistry2023-05-07T00:00:00Z2022-05-07T00:00:00Z2022-05-07info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/34428eng2047-484910.1039/d1bm01974kLadeira, Bruno M.Custódio, Catarina A.Mano, João F.info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T12:06:30Zoai:ria.ua.pt:10773/34428Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:05:45.682841Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine
title Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine
spellingShingle Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine
Ladeira, Bruno M.
Microencapsulation
Microcapsules
Core-shell structures
Tissue Engineering
Regenerative medicine
title_short Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine
title_full Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine
title_fullStr Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine
title_full_unstemmed Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine
title_sort Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine
author Ladeira, Bruno M.
author_facet Ladeira, Bruno M.
Custódio, Catarina A.
Mano, João F.
author_role author
author2 Custódio, Catarina A.
Mano, João F.
author2_role author
author
dc.contributor.author.fl_str_mv Ladeira, Bruno M.
Custódio, Catarina A.
Mano, João F.
dc.subject.por.fl_str_mv Microencapsulation
Microcapsules
Core-shell structures
Tissue Engineering
Regenerative medicine
topic Microencapsulation
Microcapsules
Core-shell structures
Tissue Engineering
Regenerative medicine
description The fabrication of scaffolds that accurately recreate the architecture of living tissues is a major challenge in the field of tissue engineering and regenerative medicine. Core-shell microcapsules hold great potential in this regard, as they can recreate the hierarchical structure of biological systems. The independent modulation of the composition of both core and shell layers allows the design of compartmentalized platforms tailored to the recreation of specific cell niches. Emergent technologies such as superhydrophobic surfaces, microfluidics, electrospray, and layer-by-layer assembly have been successful in producing core-shell microcapsules for the encapsulation of cells and bioactive factors. This review provides an overview of available materials and techniques used in the generation of core-shell microcapsules, while also highlighting some of their potential applications in the design of innovative and effective tissue engineering and regenerative medicine strategies.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-07T00:00:00Z
2022-05-07
2023-05-07T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/34428
url http://hdl.handle.net/10773/34428
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2047-4849
10.1039/d1bm01974k
dc.rights.driver.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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