Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?

Detalhes bibliográficos
Autor(a) principal: Carmelino, Janine
Data de Publicação: 2017
Outros Autores: Rodrigues, Susana, Marques, Hugo Pinto, Ribeiro, Vasco, Virella, Daniel, Alves, Marta, Martins, Américo, Barroso, Eduardo
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287
Resumo: Introduction: Biliary complications occur in 10-30% of liver transplants. The aim of this study was to compare the incidence of these complications in liver transplants when the T-tube was or was not used during the biliary anastomosis.Material and Methods: Analysis of 2 groups of patients undergoing liver transplantation between 2008 and 2012. Patients were divided considering if the T-tube was used (G1) or if it was not (G2). We sought explanatory models of the occurrence of biliary complications by logistic regression, including the variables identified in the univariate analysis.Results: We reviewed 506 consecutive patients who underwent a first liver transplant (G1 = 363, G2 = 143). The overall incidence of biliary complications was 24.7% (95% CI 21.1 to 28.6): 27.0% in G1 and 18.9% in G2 (p = 0.057). The incidences of stenosis and biliary fistula tended to be higher in G1: 19.6% (95% CI 15.7 to 23.8) vs 15.4% (95% CI 10.1 to 22.0) (p = 0.275) and 6.6% (95% CI 4.4 to 9.5) vs 2.8% (95% CI 0.9 to 6.6) (p = 0.091). We did not find statistically significant differences in the rates of endoscopic retrograde cholangiopancreatography, reoperation and retransplantation. There were two deaths in G1. There was no association between the occurrence of biliary complications and the diameters of the biliary tract nor the time of cold ischemia. The explanatory model, adjusted to the recipient and the donor age’s and to the initial diagnosis, identifies the use of the T-tube as increasing the possibility of the occurrence of biliary complications (AdjOR 1.71, 95% CI 1.04 to 2.80; p = 0.034).Discussion and Conclusion: The use of the T-tube should be a decision taken on a case-based intraoperative judgment of experienced surgeons
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spelling Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?Anastomose Biliar no Transplante Hepático: Com ou Sem Tubo em T?AnastomosisSurgicalLiver Transplantation/methodsAnastomose CirúrgicaTransplante de Fígado/métodosIntroduction: Biliary complications occur in 10-30% of liver transplants. The aim of this study was to compare the incidence of these complications in liver transplants when the T-tube was or was not used during the biliary anastomosis.Material and Methods: Analysis of 2 groups of patients undergoing liver transplantation between 2008 and 2012. Patients were divided considering if the T-tube was used (G1) or if it was not (G2). We sought explanatory models of the occurrence of biliary complications by logistic regression, including the variables identified in the univariate analysis.Results: We reviewed 506 consecutive patients who underwent a first liver transplant (G1 = 363, G2 = 143). The overall incidence of biliary complications was 24.7% (95% CI 21.1 to 28.6): 27.0% in G1 and 18.9% in G2 (p = 0.057). The incidences of stenosis and biliary fistula tended to be higher in G1: 19.6% (95% CI 15.7 to 23.8) vs 15.4% (95% CI 10.1 to 22.0) (p = 0.275) and 6.6% (95% CI 4.4 to 9.5) vs 2.8% (95% CI 0.9 to 6.6) (p = 0.091). We did not find statistically significant differences in the rates of endoscopic retrograde cholangiopancreatography, reoperation and retransplantation. There were two deaths in G1. There was no association between the occurrence of biliary complications and the diameters of the biliary tract nor the time of cold ischemia. The explanatory model, adjusted to the recipient and the donor age’s and to the initial diagnosis, identifies the use of the T-tube as increasing the possibility of the occurrence of biliary complications (AdjOR 1.71, 95% CI 1.04 to 2.80; p = 0.034).Discussion and Conclusion: The use of the T-tube should be a decision taken on a case-based intraoperative judgment of experienced surgeonsIntrodução: Complicações biliares ocorrem em 10% - 30% dos transplantes hepáticos. O objetivo deste trabalho é comparar as incidências dessas complicações nos transplantes hepáticos em que foi ou não utilizado tubo em T na anastomose biliar.Material e Métodos: Análise de dois grupos de doentes submetidos a transplante hepático entre 2008 e 2012. Consideraram-se os doentes em que o tubo em T foi utilizado (G1) e em que não o foi (G2). Procuraram-se depois modelos explicativos da ocorrência de complicações biliares por regressão logística, incluindo as variáveis identificadas na análise univariável.Resultados: Estudaram-se 506 doentes consecutivos submetidos a um primeiro transplante hepático (G1 = 363; G2 = 143). A incidência global de complicações biliares foi 24,7% (IC 95% 21,1 - 28,6): 27,0% no G1 e 18,9% no G2 (p = 0,057). As incidências de estenose e de fístula biliar foram tendencialmente mais elevadas em G1: 19,6% (IC 95% 15,7-23,8) vs 15,4% (IC 95% 10,1 - 22,0) (p = 0,275) e 6,6% (IC 95% 4,4 - 9,5) vs 2,8% (IC 95% 0,9 - 6,6) (p = 0,091). Não se encontraram diferenças estatisticamente significativas nas taxas de colangiopancreatografia retrógrada endoscópica, reoperação e retransplante. Verificaram-se dois óbitos no G1. Não se encontrou associação entre a ocorrência de complicações biliares e os diâmetros das vias biliares ou o tempo de isquemia fria. O modelo explicativo ajustado à idade do recetor e do dador, e ao diagnóstico de base identifica o uso do tubo em T como aumentando a possibilidade da ocorrência de complicações biliares (AdjOR 1,71; IC 95% 1,04 - 2,80; p = 0,034).Discussão e Conclusão: A utilização do tubo em T deve ser uma decisão tomada caso a caso e baseada no julgamento intra-operatório de cirurgiões experientes.Ordem dos Médicos2017-02-27info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/mswordapplication/mswordapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287oai:ojs.www.actamedicaportuguesa.com:article/7287Acta Médica Portuguesa; Vol. 30 No. 2 (2017): February; 122-126Acta Médica Portuguesa; Vol. 30 N.º 2 (2017): Fevereiro; 122-1261646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/4939https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/5131https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/8706https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/8913https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/9026Direitos de Autor (c) 2017 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessCarmelino, JanineRodrigues, SusanaMarques, Hugo PintoRibeiro, VascoVirella, DanielAlves, MartaMartins, AméricoBarroso, Eduardo2022-12-20T11:05:08Zoai:ojs.www.actamedicaportuguesa.com:article/7287Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:25.948653Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?
Anastomose Biliar no Transplante Hepático: Com ou Sem Tubo em T?
title Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?
spellingShingle Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?
Carmelino, Janine
Anastomosis
Surgical
Liver Transplantation/methods
Anastomose Cirúrgica
Transplante de Fígado/métodos
title_short Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?
title_full Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?
title_fullStr Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?
title_full_unstemmed Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?
title_sort Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?
author Carmelino, Janine
author_facet Carmelino, Janine
Rodrigues, Susana
Marques, Hugo Pinto
Ribeiro, Vasco
Virella, Daniel
Alves, Marta
Martins, Américo
Barroso, Eduardo
author_role author
author2 Rodrigues, Susana
Marques, Hugo Pinto
Ribeiro, Vasco
Virella, Daniel
Alves, Marta
Martins, Américo
Barroso, Eduardo
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Carmelino, Janine
Rodrigues, Susana
Marques, Hugo Pinto
Ribeiro, Vasco
Virella, Daniel
Alves, Marta
Martins, Américo
Barroso, Eduardo
dc.subject.por.fl_str_mv Anastomosis
Surgical
Liver Transplantation/methods
Anastomose Cirúrgica
Transplante de Fígado/métodos
topic Anastomosis
Surgical
Liver Transplantation/methods
Anastomose Cirúrgica
Transplante de Fígado/métodos
description Introduction: Biliary complications occur in 10-30% of liver transplants. The aim of this study was to compare the incidence of these complications in liver transplants when the T-tube was or was not used during the biliary anastomosis.Material and Methods: Analysis of 2 groups of patients undergoing liver transplantation between 2008 and 2012. Patients were divided considering if the T-tube was used (G1) or if it was not (G2). We sought explanatory models of the occurrence of biliary complications by logistic regression, including the variables identified in the univariate analysis.Results: We reviewed 506 consecutive patients who underwent a first liver transplant (G1 = 363, G2 = 143). The overall incidence of biliary complications was 24.7% (95% CI 21.1 to 28.6): 27.0% in G1 and 18.9% in G2 (p = 0.057). The incidences of stenosis and biliary fistula tended to be higher in G1: 19.6% (95% CI 15.7 to 23.8) vs 15.4% (95% CI 10.1 to 22.0) (p = 0.275) and 6.6% (95% CI 4.4 to 9.5) vs 2.8% (95% CI 0.9 to 6.6) (p = 0.091). We did not find statistically significant differences in the rates of endoscopic retrograde cholangiopancreatography, reoperation and retransplantation. There were two deaths in G1. There was no association between the occurrence of biliary complications and the diameters of the biliary tract nor the time of cold ischemia. The explanatory model, adjusted to the recipient and the donor age’s and to the initial diagnosis, identifies the use of the T-tube as increasing the possibility of the occurrence of biliary complications (AdjOR 1.71, 95% CI 1.04 to 2.80; p = 0.034).Discussion and Conclusion: The use of the T-tube should be a decision taken on a case-based intraoperative judgment of experienced surgeons
publishDate 2017
dc.date.none.fl_str_mv 2017-02-27
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dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/4939
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/5131
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/8706
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/8913
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/9026
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2017 Acta Médica Portuguesa
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 30 No. 2 (2017): February; 122-126
Acta Médica Portuguesa; Vol. 30 N.º 2 (2017): Fevereiro; 122-126
1646-0758
0870-399X
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