Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287 |
Resumo: | Introduction: Biliary complications occur in 10-30% of liver transplants. The aim of this study was to compare the incidence of these complications in liver transplants when the T-tube was or was not used during the biliary anastomosis.Material and Methods: Analysis of 2 groups of patients undergoing liver transplantation between 2008 and 2012. Patients were divided considering if the T-tube was used (G1) or if it was not (G2). We sought explanatory models of the occurrence of biliary complications by logistic regression, including the variables identified in the univariate analysis.Results: We reviewed 506 consecutive patients who underwent a first liver transplant (G1 = 363, G2 = 143). The overall incidence of biliary complications was 24.7% (95% CI 21.1 to 28.6): 27.0% in G1 and 18.9% in G2 (p = 0.057). The incidences of stenosis and biliary fistula tended to be higher in G1: 19.6% (95% CI 15.7 to 23.8) vs 15.4% (95% CI 10.1 to 22.0) (p = 0.275) and 6.6% (95% CI 4.4 to 9.5) vs 2.8% (95% CI 0.9 to 6.6) (p = 0.091). We did not find statistically significant differences in the rates of endoscopic retrograde cholangiopancreatography, reoperation and retransplantation. There were two deaths in G1. There was no association between the occurrence of biliary complications and the diameters of the biliary tract nor the time of cold ischemia. The explanatory model, adjusted to the recipient and the donor age’s and to the initial diagnosis, identifies the use of the T-tube as increasing the possibility of the occurrence of biliary complications (AdjOR 1.71, 95% CI 1.04 to 2.80; p = 0.034).Discussion and Conclusion: The use of the T-tube should be a decision taken on a case-based intraoperative judgment of experienced surgeons |
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Biliary Anastomosis in Liver Transplantation: With or Without T-Tube?Anastomose Biliar no Transplante Hepático: Com ou Sem Tubo em T?AnastomosisSurgicalLiver Transplantation/methodsAnastomose CirúrgicaTransplante de Fígado/métodosIntroduction: Biliary complications occur in 10-30% of liver transplants. The aim of this study was to compare the incidence of these complications in liver transplants when the T-tube was or was not used during the biliary anastomosis.Material and Methods: Analysis of 2 groups of patients undergoing liver transplantation between 2008 and 2012. Patients were divided considering if the T-tube was used (G1) or if it was not (G2). We sought explanatory models of the occurrence of biliary complications by logistic regression, including the variables identified in the univariate analysis.Results: We reviewed 506 consecutive patients who underwent a first liver transplant (G1 = 363, G2 = 143). The overall incidence of biliary complications was 24.7% (95% CI 21.1 to 28.6): 27.0% in G1 and 18.9% in G2 (p = 0.057). The incidences of stenosis and biliary fistula tended to be higher in G1: 19.6% (95% CI 15.7 to 23.8) vs 15.4% (95% CI 10.1 to 22.0) (p = 0.275) and 6.6% (95% CI 4.4 to 9.5) vs 2.8% (95% CI 0.9 to 6.6) (p = 0.091). We did not find statistically significant differences in the rates of endoscopic retrograde cholangiopancreatography, reoperation and retransplantation. There were two deaths in G1. There was no association between the occurrence of biliary complications and the diameters of the biliary tract nor the time of cold ischemia. The explanatory model, adjusted to the recipient and the donor age’s and to the initial diagnosis, identifies the use of the T-tube as increasing the possibility of the occurrence of biliary complications (AdjOR 1.71, 95% CI 1.04 to 2.80; p = 0.034).Discussion and Conclusion: The use of the T-tube should be a decision taken on a case-based intraoperative judgment of experienced surgeonsIntrodução: Complicações biliares ocorrem em 10% - 30% dos transplantes hepáticos. O objetivo deste trabalho é comparar as incidências dessas complicações nos transplantes hepáticos em que foi ou não utilizado tubo em T na anastomose biliar.Material e Métodos: Análise de dois grupos de doentes submetidos a transplante hepático entre 2008 e 2012. Consideraram-se os doentes em que o tubo em T foi utilizado (G1) e em que não o foi (G2). Procuraram-se depois modelos explicativos da ocorrência de complicações biliares por regressão logística, incluindo as variáveis identificadas na análise univariável.Resultados: Estudaram-se 506 doentes consecutivos submetidos a um primeiro transplante hepático (G1 = 363; G2 = 143). A incidência global de complicações biliares foi 24,7% (IC 95% 21,1 - 28,6): 27,0% no G1 e 18,9% no G2 (p = 0,057). As incidências de estenose e de fístula biliar foram tendencialmente mais elevadas em G1: 19,6% (IC 95% 15,7-23,8) vs 15,4% (IC 95% 10,1 - 22,0) (p = 0,275) e 6,6% (IC 95% 4,4 - 9,5) vs 2,8% (IC 95% 0,9 - 6,6) (p = 0,091). Não se encontraram diferenças estatisticamente significativas nas taxas de colangiopancreatografia retrógrada endoscópica, reoperação e retransplante. Verificaram-se dois óbitos no G1. Não se encontrou associação entre a ocorrência de complicações biliares e os diâmetros das vias biliares ou o tempo de isquemia fria. O modelo explicativo ajustado à idade do recetor e do dador, e ao diagnóstico de base identifica o uso do tubo em T como aumentando a possibilidade da ocorrência de complicações biliares (AdjOR 1,71; IC 95% 1,04 - 2,80; p = 0,034).Discussão e Conclusão: A utilização do tubo em T deve ser uma decisão tomada caso a caso e baseada no julgamento intra-operatório de cirurgiões experientes.Ordem dos Médicos2017-02-27info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/mswordapplication/mswordapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287oai:ojs.www.actamedicaportuguesa.com:article/7287Acta Médica Portuguesa; Vol. 30 No. 2 (2017): February; 122-126Acta Médica Portuguesa; Vol. 30 N.º 2 (2017): Fevereiro; 122-1261646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/4939https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/5131https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/8706https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/8913https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/9026Direitos de Autor (c) 2017 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessCarmelino, JanineRodrigues, SusanaMarques, Hugo PintoRibeiro, VascoVirella, DanielAlves, MartaMartins, AméricoBarroso, Eduardo2022-12-20T11:05:08Zoai:ojs.www.actamedicaportuguesa.com:article/7287Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:25.948653Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Biliary Anastomosis in Liver Transplantation: With or Without T-Tube? Anastomose Biliar no Transplante Hepático: Com ou Sem Tubo em T? |
title |
Biliary Anastomosis in Liver Transplantation: With or Without T-Tube? |
spellingShingle |
Biliary Anastomosis in Liver Transplantation: With or Without T-Tube? Carmelino, Janine Anastomosis Surgical Liver Transplantation/methods Anastomose Cirúrgica Transplante de Fígado/métodos |
title_short |
Biliary Anastomosis in Liver Transplantation: With or Without T-Tube? |
title_full |
Biliary Anastomosis in Liver Transplantation: With or Without T-Tube? |
title_fullStr |
Biliary Anastomosis in Liver Transplantation: With or Without T-Tube? |
title_full_unstemmed |
Biliary Anastomosis in Liver Transplantation: With or Without T-Tube? |
title_sort |
Biliary Anastomosis in Liver Transplantation: With or Without T-Tube? |
author |
Carmelino, Janine |
author_facet |
Carmelino, Janine Rodrigues, Susana Marques, Hugo Pinto Ribeiro, Vasco Virella, Daniel Alves, Marta Martins, Américo Barroso, Eduardo |
author_role |
author |
author2 |
Rodrigues, Susana Marques, Hugo Pinto Ribeiro, Vasco Virella, Daniel Alves, Marta Martins, Américo Barroso, Eduardo |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Carmelino, Janine Rodrigues, Susana Marques, Hugo Pinto Ribeiro, Vasco Virella, Daniel Alves, Marta Martins, Américo Barroso, Eduardo |
dc.subject.por.fl_str_mv |
Anastomosis Surgical Liver Transplantation/methods Anastomose Cirúrgica Transplante de Fígado/métodos |
topic |
Anastomosis Surgical Liver Transplantation/methods Anastomose Cirúrgica Transplante de Fígado/métodos |
description |
Introduction: Biliary complications occur in 10-30% of liver transplants. The aim of this study was to compare the incidence of these complications in liver transplants when the T-tube was or was not used during the biliary anastomosis.Material and Methods: Analysis of 2 groups of patients undergoing liver transplantation between 2008 and 2012. Patients were divided considering if the T-tube was used (G1) or if it was not (G2). We sought explanatory models of the occurrence of biliary complications by logistic regression, including the variables identified in the univariate analysis.Results: We reviewed 506 consecutive patients who underwent a first liver transplant (G1 = 363, G2 = 143). The overall incidence of biliary complications was 24.7% (95% CI 21.1 to 28.6): 27.0% in G1 and 18.9% in G2 (p = 0.057). The incidences of stenosis and biliary fistula tended to be higher in G1: 19.6% (95% CI 15.7 to 23.8) vs 15.4% (95% CI 10.1 to 22.0) (p = 0.275) and 6.6% (95% CI 4.4 to 9.5) vs 2.8% (95% CI 0.9 to 6.6) (p = 0.091). We did not find statistically significant differences in the rates of endoscopic retrograde cholangiopancreatography, reoperation and retransplantation. There were two deaths in G1. There was no association between the occurrence of biliary complications and the diameters of the biliary tract nor the time of cold ischemia. The explanatory model, adjusted to the recipient and the donor age’s and to the initial diagnosis, identifies the use of the T-tube as increasing the possibility of the occurrence of biliary complications (AdjOR 1.71, 95% CI 1.04 to 2.80; p = 0.034).Discussion and Conclusion: The use of the T-tube should be a decision taken on a case-based intraoperative judgment of experienced surgeons |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-02-27 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287 oai:ojs.www.actamedicaportuguesa.com:article/7287 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/7287 |
dc.language.iso.fl_str_mv |
por eng |
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por eng |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/4939 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/5131 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/8706 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/8913 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7287/9026 |
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Direitos de Autor (c) 2017 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
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Direitos de Autor (c) 2017 Acta Médica Portuguesa |
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openAccess |
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application/pdf application/pdf application/msword application/msword application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
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Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 30 No. 2 (2017): February; 122-126 Acta Médica Portuguesa; Vol. 30 N.º 2 (2017): Fevereiro; 122-126 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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