Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?

Detalhes bibliográficos
Autor(a) principal: Serranito, Laura
Data de Publicação: 2022
Outros Autores: Reis-Pina, Paulo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932
Resumo: The aim of this case is to clarify the need to maintain the terminally ill oncological patients who have had a thrombotic event in the course of their underlying disease under antithrombotic therapy. This case addresses a 63-year-old man with stage IV gastric antrum adenocarcinoma, completely bed-ridden and anticoagulated with subcutaneous enoxaparin for more than a year, following deep venous thrombosis of the left lower limb. After reviewing the literature, it was found that, for end-of-life patients, anticoagulation seems to have little benefit as the main objective is not the extension of life itself, but rather the preservation of the best quality of life through practices that are well established in the relief of suffering.
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spelling Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?Profilaxia Farmacológica do Tromboembolismo Venoso em Doentes Terminais: Uma Necessidade ou um Desperdício?Anticoagulants/therapeutic useEnoxaparinFibrinolytic AgentsPalliative CareVenous Thromboembolism/prevention & controlThe aim of this case is to clarify the need to maintain the terminally ill oncological patients who have had a thrombotic event in the course of their underlying disease under antithrombotic therapy. This case addresses a 63-year-old man with stage IV gastric antrum adenocarcinoma, completely bed-ridden and anticoagulated with subcutaneous enoxaparin for more than a year, following deep venous thrombosis of the left lower limb. After reviewing the literature, it was found that, for end-of-life patients, anticoagulation seems to have little benefit as the main objective is not the extension of life itself, but rather the preservation of the best quality of life through practices that are well established in the relief of suffering.O presente caso pretende clarificar qual a verdadeira necessidade de manter sob terapêutica anti-trombótica os doentes oncológicos terminais que tiveram um evento trombótico no decorrer da evolução da sua doença de base. O caso em questão aborda um doente de 63 anos com uma neoplasia do antro gástrico em estadio IV, totalmente acamado, hipocoagulado com enoxaparina subcutânea há mais de um ano, no seguimento de uma trombose venosa profunda no membro inferior esquerdo. Após revisão da literatura, constatou-se que em doentes em fim de vida, a anticoagulação parece ter pouco benefício, visto que o principal objetivo não é o prolongamento da vida, mas sim a preservação da melhor qualidade de vida possível através de práticas cuja evidência no alívio do sofrimento está bem documentada.Ordem dos Médicos2022-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932oai:ojs.www.actamedicaportuguesa.com:article/12932Acta Médica Portuguesa; Vol. 35 No. 2 (2022): February; 147-149Acta Médica Portuguesa; Vol. 35 N.º 2 (2022): Fevereiro; 147-1491646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/6258https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/11907https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/11948https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/12412https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/12900Direitos de Autor (c) 2021 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessSerranito, LauraReis-Pina, Paulo2022-12-20T11:06:44Zoai:ojs.www.actamedicaportuguesa.com:article/12932Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:15.220199Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?
Profilaxia Farmacológica do Tromboembolismo Venoso em Doentes Terminais: Uma Necessidade ou um Desperdício?
title Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?
spellingShingle Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?
Serranito, Laura
Anticoagulants/therapeutic use
Enoxaparin
Fibrinolytic Agents
Palliative Care
Venous Thromboembolism/prevention & control
title_short Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?
title_full Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?
title_fullStr Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?
title_full_unstemmed Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?
title_sort Pharmacological Prophylaxis of Venous Thromboembolism in Terminally Ill Patients: A Need or Futility?
author Serranito, Laura
author_facet Serranito, Laura
Reis-Pina, Paulo
author_role author
author2 Reis-Pina, Paulo
author2_role author
dc.contributor.author.fl_str_mv Serranito, Laura
Reis-Pina, Paulo
dc.subject.por.fl_str_mv Anticoagulants/therapeutic use
Enoxaparin
Fibrinolytic Agents
Palliative Care
Venous Thromboembolism/prevention & control
topic Anticoagulants/therapeutic use
Enoxaparin
Fibrinolytic Agents
Palliative Care
Venous Thromboembolism/prevention & control
description The aim of this case is to clarify the need to maintain the terminally ill oncological patients who have had a thrombotic event in the course of their underlying disease under antithrombotic therapy. This case addresses a 63-year-old man with stage IV gastric antrum adenocarcinoma, completely bed-ridden and anticoagulated with subcutaneous enoxaparin for more than a year, following deep venous thrombosis of the left lower limb. After reviewing the literature, it was found that, for end-of-life patients, anticoagulation seems to have little benefit as the main objective is not the extension of life itself, but rather the preservation of the best quality of life through practices that are well established in the relief of suffering.
publishDate 2022
dc.date.none.fl_str_mv 2022-02-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932
oai:ojs.www.actamedicaportuguesa.com:article/12932
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/12932
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/6258
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/11907
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/11948
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/12412
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12932/12900
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2021 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2021 Acta Médica Portuguesa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/vnd.openxmlformats-officedocument.wordprocessingml.document
application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 35 No. 2 (2022): February; 147-149
Acta Médica Portuguesa; Vol. 35 N.º 2 (2022): Fevereiro; 147-149
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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