A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depression

Detalhes bibliográficos
Autor(a) principal: Silva dos Santos, Amílcar
Data de Publicação: 2021
Outros Autores: Sales, Miguel, Sebastião, Ana M, Gusmão, Ricardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/47559
Resumo: Copyright © 2021 Silva-dos-Santos, Sales, Sebastião and Gusmão. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
id RCAP_1fd2b8a7a7d8572ebd4d3a10494342ac
oai_identifier_str oai:repositorio.ul.pt:10451/47559
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depressionParkinson's diseaseDeep brain stimulationDepressionEtiopathogenesisMental kindling-like mechanismTreatment-resistant depressionCopyright © 2021 Silva-dos-Santos, Sales, Sebastião and Gusmão. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.In this opinion article, we humbly propose a new viewpoint on the etiopathogenesis of depression. We base the model on our interpretation of selected recent neurophysiological findings, mainly regarding Deep Brain Stimulation (DBS) to treat Parkinson’s Disease and also DBS to treat Treatment-Resistant Depression (TRD). We coin the idea a mental kindling-like mechanism. However, future clinical research, possibly complemented with human laboratory research or animal experiments, will be needed to test the validity of our proposed model. On the current manuscript framework, following the first and introductory section, we will set the stage by presenting selected studies and insights mainly from DBS to treat TRD and PD, on the second and middle section. Finally, we will discuss the proposed viewpoint on the third and last section of the present work.FrontiersRepositório da Universidade de LisboaSilva dos Santos, AmílcarSales, MiguelSebastião, Ana MGusmão, Ricardo2021-04-27T11:08:34Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/47559engFront Psychiatry. 2021 Apr 9;12:60733910.3389/fpsyt.2021.6073391664-0640info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:50:34Zoai:repositorio.ul.pt:10451/47559Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:59:34.814154Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depression
title A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depression
spellingShingle A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depression
Silva dos Santos, Amílcar
Parkinson's disease
Deep brain stimulation
Depression
Etiopathogenesis
Mental kindling-like mechanism
Treatment-resistant depression
title_short A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depression
title_full A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depression
title_fullStr A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depression
title_full_unstemmed A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depression
title_sort A new viewpoint on the etiopathogenesis of depression : insights from the neurophysiology of deep brain stimulation in Parkinson's Disease and treatment-resistant depression
author Silva dos Santos, Amílcar
author_facet Silva dos Santos, Amílcar
Sales, Miguel
Sebastião, Ana M
Gusmão, Ricardo
author_role author
author2 Sales, Miguel
Sebastião, Ana M
Gusmão, Ricardo
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Silva dos Santos, Amílcar
Sales, Miguel
Sebastião, Ana M
Gusmão, Ricardo
dc.subject.por.fl_str_mv Parkinson's disease
Deep brain stimulation
Depression
Etiopathogenesis
Mental kindling-like mechanism
Treatment-resistant depression
topic Parkinson's disease
Deep brain stimulation
Depression
Etiopathogenesis
Mental kindling-like mechanism
Treatment-resistant depression
description Copyright © 2021 Silva-dos-Santos, Sales, Sebastião and Gusmão. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
publishDate 2021
dc.date.none.fl_str_mv 2021-04-27T11:08:34Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/47559
url http://hdl.handle.net/10451/47559
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Front Psychiatry. 2021 Apr 9;12:607339
10.3389/fpsyt.2021.607339
1664-0640
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers
publisher.none.fl_str_mv Frontiers
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799134541984563200

Registros relacionados