Coupled variability in primary sensory areas and the hippocampus during spontaneous activity

Detalhes bibliográficos
Autor(a) principal: Vasconcelos, Nivaldo A. P. de
Data de Publicação: 2017
Outros Autores: Cunha, Carina Isabel Soares, Rodrigues, Ana João, Ribeiro, Sidarta, Sousa, Nuno
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/49089
Resumo: The cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time. The structural features of spiking activity in sensory cortices have been characterized during spontaneous and evoked activity. However, the coordination among cortical and sub-cortical neurons during spontaneous activity across different states remains poorly characterized. We addressed this issue by studying the temporal coupling of spiking variability recorded from primary sensory cortices and hippocampus of anesthetized or freely behaving rats. During spontaneous activity, spiking variability was highly correlated across primary cortical sensory areas at both small and large spatial scales, whereas the cortico-hippocampal correlation was modest. This general pattern of spiking variability was observed under urethane anesthesia, as well as during waking, slow-wave sleep and rapid-eye-movement sleep, and was unchanged by novel stimulation. These results support the notion that primary sensory areas are strongly coupled during spontaneous activity.
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spelling Coupled variability in primary sensory areas and the hippocampus during spontaneous activityCiências Médicas::Medicina BásicaScience & TechnologyThe cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time. The structural features of spiking activity in sensory cortices have been characterized during spontaneous and evoked activity. However, the coordination among cortical and sub-cortical neurons during spontaneous activity across different states remains poorly characterized. We addressed this issue by studying the temporal coupling of spiking variability recorded from primary sensory cortices and hippocampus of anesthetized or freely behaving rats. During spontaneous activity, spiking variability was highly correlated across primary cortical sensory areas at both small and large spatial scales, whereas the cortico-hippocampal correlation was modest. This general pattern of spiking variability was observed under urethane anesthesia, as well as during waking, slow-wave sleep and rapid-eye-movement sleep, and was unchanged by novel stimulation. These results support the notion that primary sensory areas are strongly coupled during spontaneous activity.project NORTE-01-0145-FEDER-000013, supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER). NAPV was supported by Centro Universitario do Rio Grande do Norte, Champalimaud Foundation, and Brazilian National Council for Scientific and Technological Development (CNPq, Grant 249991/2013-6), CC-S (SFRH/BD/51992/2012). AJR (IF/00883/2013). SR by UFRN, CNPq (Research Productivity Grant 308775/2015-5), and S. Paulo Research Foundation FAPESP - Center for Neuromathematics (Grant 2013/07699-0)info:eu-repo/semantics/publishedVersionNature Publishing GroupUniversidade do MinhoVasconcelos, Nivaldo A. P. deCunha, Carina Isabel SoaresRodrigues, Ana JoãoRibeiro, SidartaSousa, Nuno2017-04-102017-04-10T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/49089engDe Vasconcelos, N. A., Soares-Cunha, C., Rodrigues, A. J., Ribeiro, S., & Sousa, N. (2017). Coupled variability in primary sensory areas and the hippocampus during spontaneous activity. Scientific Reports, 72045-232210.1038/srep4607728393914https://www.nature.com/articles/srep46077info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:01:20Zoai:repositorium.sdum.uminho.pt:1822/49089Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:51:15.325327Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Coupled variability in primary sensory areas and the hippocampus during spontaneous activity
title Coupled variability in primary sensory areas and the hippocampus during spontaneous activity
spellingShingle Coupled variability in primary sensory areas and the hippocampus during spontaneous activity
Vasconcelos, Nivaldo A. P. de
Ciências Médicas::Medicina Básica
Science & Technology
title_short Coupled variability in primary sensory areas and the hippocampus during spontaneous activity
title_full Coupled variability in primary sensory areas and the hippocampus during spontaneous activity
title_fullStr Coupled variability in primary sensory areas and the hippocampus during spontaneous activity
title_full_unstemmed Coupled variability in primary sensory areas and the hippocampus during spontaneous activity
title_sort Coupled variability in primary sensory areas and the hippocampus during spontaneous activity
author Vasconcelos, Nivaldo A. P. de
author_facet Vasconcelos, Nivaldo A. P. de
Cunha, Carina Isabel Soares
Rodrigues, Ana João
Ribeiro, Sidarta
Sousa, Nuno
author_role author
author2 Cunha, Carina Isabel Soares
Rodrigues, Ana João
Ribeiro, Sidarta
Sousa, Nuno
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Vasconcelos, Nivaldo A. P. de
Cunha, Carina Isabel Soares
Rodrigues, Ana João
Ribeiro, Sidarta
Sousa, Nuno
dc.subject.por.fl_str_mv Ciências Médicas::Medicina Básica
Science & Technology
topic Ciências Médicas::Medicina Básica
Science & Technology
description The cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time. The structural features of spiking activity in sensory cortices have been characterized during spontaneous and evoked activity. However, the coordination among cortical and sub-cortical neurons during spontaneous activity across different states remains poorly characterized. We addressed this issue by studying the temporal coupling of spiking variability recorded from primary sensory cortices and hippocampus of anesthetized or freely behaving rats. During spontaneous activity, spiking variability was highly correlated across primary cortical sensory areas at both small and large spatial scales, whereas the cortico-hippocampal correlation was modest. This general pattern of spiking variability was observed under urethane anesthesia, as well as during waking, slow-wave sleep and rapid-eye-movement sleep, and was unchanged by novel stimulation. These results support the notion that primary sensory areas are strongly coupled during spontaneous activity.
publishDate 2017
dc.date.none.fl_str_mv 2017-04-10
2017-04-10T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/49089
url http://hdl.handle.net/1822/49089
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv De Vasconcelos, N. A., Soares-Cunha, C., Rodrigues, A. J., Ribeiro, S., & Sousa, N. (2017). Coupled variability in primary sensory areas and the hippocampus during spontaneous activity. Scientific Reports, 7
2045-2322
10.1038/srep46077
28393914
https://www.nature.com/articles/srep46077
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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