Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide Registry
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/3350 |
Resumo: | BACKGROUND: In previous guidelines, intra-aortic balloon pump (IABP) use was strongly recommended in the treatment of cardiogenic shock in the context of acute myocardial infarction. The recent IABP-SHOCK II trial demonstrated no benefit in short- and medium-term mortality with the use of IABP. It was our objective to evaluate in a real life nationwide population of patients with acute myocardial infarction the impact of IABP in short- and medium-term mortality. METHODS: We included patients admitted with acute myocardial infarction in Killip class IV in the first 24 hours, all submitted to urgent coronary angiography. Our study objective was the occurrence of hospital and six-month all-cause mortality. RESULTS: From the 33,300 patients included in the registry, 4.2% presented with Killip class IV in the first 24 hours and 646 (43.6%) were submitted to urgent coronary angiography. IABP was implanted in 19.8% of these patients. The IABP group was younger, had higher admission heart rate, more multivessel disease and more left main disease. There were 260 hospital deaths (40.2%), similar between groups (46.1% vs. 38.8%, p=0.132). IABP use was associated with a deleterious effect in patients with previous MI and beneficial effect in patients with mechanical complications. IABP use had a neutral effect on mortality (hazard ratio 1.14, 95% confidence interval 0.84-1.56). This was further confirmed in a propensity score matching analysis. CONCLUSIONS: In a real life population of patients with acute myocardial infarction, the use of IABP for the treatment of cardiogenic shock was associated with a neutral effect. |
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Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide RegistryAgedAged, 80 and overCoronary AngiographyFemaleHumansIntra-Aortic Balloon PumpingMaleMiddle AgedMyocardial InfarctionPortugalPropensity ScoreRegistriesShock, CardiogenicHSM CARBACKGROUND: In previous guidelines, intra-aortic balloon pump (IABP) use was strongly recommended in the treatment of cardiogenic shock in the context of acute myocardial infarction. The recent IABP-SHOCK II trial demonstrated no benefit in short- and medium-term mortality with the use of IABP. It was our objective to evaluate in a real life nationwide population of patients with acute myocardial infarction the impact of IABP in short- and medium-term mortality. METHODS: We included patients admitted with acute myocardial infarction in Killip class IV in the first 24 hours, all submitted to urgent coronary angiography. Our study objective was the occurrence of hospital and six-month all-cause mortality. RESULTS: From the 33,300 patients included in the registry, 4.2% presented with Killip class IV in the first 24 hours and 646 (43.6%) were submitted to urgent coronary angiography. IABP was implanted in 19.8% of these patients. The IABP group was younger, had higher admission heart rate, more multivessel disease and more left main disease. There were 260 hospital deaths (40.2%), similar between groups (46.1% vs. 38.8%, p=0.132). IABP use was associated with a deleterious effect in patients with previous MI and beneficial effect in patients with mechanical complications. IABP use had a neutral effect on mortality (hazard ratio 1.14, 95% confidence interval 0.84-1.56). This was further confirmed in a propensity score matching analysis. CONCLUSIONS: In a real life population of patients with acute myocardial infarction, the use of IABP for the treatment of cardiogenic shock was associated with a neutral effect.SAGE PublicationsRepositório do Centro Hospitalar Universitário de Lisboa Central, EPETimóteo, ATNogueira, MAguiar Rosa, SBelo, ACruz Ferreira, R2019-11-11T16:26:21Z2016-112016-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/3350engEur Heart J Acute Cardiovasc Care. 2016 Nov;5(7):23-31.10.1177/2048872615606600info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:42:31Zoai:repositorio.chlc.min-saude.pt:10400.17/3350Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:20:39.967719Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide Registry |
title |
Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide Registry |
spellingShingle |
Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide Registry Timóteo, AT Aged Aged, 80 and over Coronary Angiography Female Humans Intra-Aortic Balloon Pumping Male Middle Aged Myocardial Infarction Portugal Propensity Score Registries Shock, Cardiogenic HSM CAR |
title_short |
Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide Registry |
title_full |
Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide Registry |
title_fullStr |
Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide Registry |
title_full_unstemmed |
Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide Registry |
title_sort |
Role of Intra-Aortic Balloon Pump Counterpulsation in the Treatment of Acute Myocardial Infarction Complicated by Cardiogenic Shock: Evidence from the Portuguese Nationwide Registry |
author |
Timóteo, AT |
author_facet |
Timóteo, AT Nogueira, M Aguiar Rosa, S Belo, A Cruz Ferreira, R |
author_role |
author |
author2 |
Nogueira, M Aguiar Rosa, S Belo, A Cruz Ferreira, R |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Timóteo, AT Nogueira, M Aguiar Rosa, S Belo, A Cruz Ferreira, R |
dc.subject.por.fl_str_mv |
Aged Aged, 80 and over Coronary Angiography Female Humans Intra-Aortic Balloon Pumping Male Middle Aged Myocardial Infarction Portugal Propensity Score Registries Shock, Cardiogenic HSM CAR |
topic |
Aged Aged, 80 and over Coronary Angiography Female Humans Intra-Aortic Balloon Pumping Male Middle Aged Myocardial Infarction Portugal Propensity Score Registries Shock, Cardiogenic HSM CAR |
description |
BACKGROUND: In previous guidelines, intra-aortic balloon pump (IABP) use was strongly recommended in the treatment of cardiogenic shock in the context of acute myocardial infarction. The recent IABP-SHOCK II trial demonstrated no benefit in short- and medium-term mortality with the use of IABP. It was our objective to evaluate in a real life nationwide population of patients with acute myocardial infarction the impact of IABP in short- and medium-term mortality. METHODS: We included patients admitted with acute myocardial infarction in Killip class IV in the first 24 hours, all submitted to urgent coronary angiography. Our study objective was the occurrence of hospital and six-month all-cause mortality. RESULTS: From the 33,300 patients included in the registry, 4.2% presented with Killip class IV in the first 24 hours and 646 (43.6%) were submitted to urgent coronary angiography. IABP was implanted in 19.8% of these patients. The IABP group was younger, had higher admission heart rate, more multivessel disease and more left main disease. There were 260 hospital deaths (40.2%), similar between groups (46.1% vs. 38.8%, p=0.132). IABP use was associated with a deleterious effect in patients with previous MI and beneficial effect in patients with mechanical complications. IABP use had a neutral effect on mortality (hazard ratio 1.14, 95% confidence interval 0.84-1.56). This was further confirmed in a propensity score matching analysis. CONCLUSIONS: In a real life population of patients with acute myocardial infarction, the use of IABP for the treatment of cardiogenic shock was associated with a neutral effect. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-11 2016-11-01T00:00:00Z 2019-11-11T16:26:21Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/3350 |
url |
http://hdl.handle.net/10400.17/3350 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Eur Heart J Acute Cardiovasc Care. 2016 Nov;5(7):23-31. 10.1177/2048872615606600 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
SAGE Publications |
publisher.none.fl_str_mv |
SAGE Publications |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799131302678495232 |