Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of wounds
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.22/18298 |
Resumo: | Wounds affect one’s quality of life and should be managed on a patient-specific approach, based on the particular healing phase and wound condition. During wound healing, exudate is produced as a natural response towards healing. However, excessive production can be detrimental, representing a challenge for wound management. The design and development of new healing devices and therapeutics with improved performance is a constant demand from the healthcare services. Aerogels can combine high porosity and low density with the adequate fluid interaction and drug loading capacity, to establish hemostasis and promote the healing and regeneration of exudative and chronic wounds. Bio-based aerogels, i.e., those produced from natural polymers, are particularly attractive since they encompass their intrinsic chemical properties and the physical features of their nanostructure. In this work, the emerging research on aerogels for wound treatment is reviewed for the first time. The current scenario and the opportunities provided by aerogels in the form of films, membranes and particles are identified to face current unmet demands in fluid managing and wound healing and regeneration. |
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Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of woundsAerogelsBiopolymerExudateWound healingWounds affect one’s quality of life and should be managed on a patient-specific approach, based on the particular healing phase and wound condition. During wound healing, exudate is produced as a natural response towards healing. However, excessive production can be detrimental, representing a challenge for wound management. The design and development of new healing devices and therapeutics with improved performance is a constant demand from the healthcare services. Aerogels can combine high porosity and low density with the adequate fluid interaction and drug loading capacity, to establish hemostasis and promote the healing and regeneration of exudative and chronic wounds. Bio-based aerogels, i.e., those produced from natural polymers, are particularly attractive since they encompass their intrinsic chemical properties and the physical features of their nanostructure. In this work, the emerging research on aerogels for wound treatment is reviewed for the first time. The current scenario and the opportunities provided by aerogels in the form of films, membranes and particles are identified to face current unmet demands in fluid managing and wound healing and regeneration.MDPIRepositório Científico do Instituto Politécnico do PortoG. Bernardes, BeatrizDel Gaudio, PasqualeAlves, PauloCosta, RaquelA. Garcia-Gonzalez, CarlosLeite Oliveira, Ana2021-09-02T14:41:12Z2021-06-232021-06-23T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/18298engBernardes, B. G., Del Gaudio, P., Alves, P., Costa, R., García-Gonzaléz, C. A., & Oliveira, A. L. (2021). Bioaerogels: Promising Nanostructured Materials in Fluid Management, Healing and Regeneration of Wounds. Molecules, 26(13), 3834. https://www.mdpi.com/1420-3049/26/13/38341420-304910.3390/molecules26133834info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-10T01:49:17Zoai:recipp.ipp.pt:10400.22/18298Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:37:58.144294Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of wounds |
title |
Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of wounds |
spellingShingle |
Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of wounds G. Bernardes, Beatriz Aerogels Biopolymer Exudate Wound healing |
title_short |
Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of wounds |
title_full |
Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of wounds |
title_fullStr |
Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of wounds |
title_full_unstemmed |
Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of wounds |
title_sort |
Bioaerogels: promising nanostructured materials in fluid management, healing and regeneration of wounds |
author |
G. Bernardes, Beatriz |
author_facet |
G. Bernardes, Beatriz Del Gaudio, Pasquale Alves, Paulo Costa, Raquel A. Garcia-Gonzalez, Carlos Leite Oliveira, Ana |
author_role |
author |
author2 |
Del Gaudio, Pasquale Alves, Paulo Costa, Raquel A. Garcia-Gonzalez, Carlos Leite Oliveira, Ana |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Politécnico do Porto |
dc.contributor.author.fl_str_mv |
G. Bernardes, Beatriz Del Gaudio, Pasquale Alves, Paulo Costa, Raquel A. Garcia-Gonzalez, Carlos Leite Oliveira, Ana |
dc.subject.por.fl_str_mv |
Aerogels Biopolymer Exudate Wound healing |
topic |
Aerogels Biopolymer Exudate Wound healing |
description |
Wounds affect one’s quality of life and should be managed on a patient-specific approach, based on the particular healing phase and wound condition. During wound healing, exudate is produced as a natural response towards healing. However, excessive production can be detrimental, representing a challenge for wound management. The design and development of new healing devices and therapeutics with improved performance is a constant demand from the healthcare services. Aerogels can combine high porosity and low density with the adequate fluid interaction and drug loading capacity, to establish hemostasis and promote the healing and regeneration of exudative and chronic wounds. Bio-based aerogels, i.e., those produced from natural polymers, are particularly attractive since they encompass their intrinsic chemical properties and the physical features of their nanostructure. In this work, the emerging research on aerogels for wound treatment is reviewed for the first time. The current scenario and the opportunities provided by aerogels in the form of films, membranes and particles are identified to face current unmet demands in fluid managing and wound healing and regeneration. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-09-02T14:41:12Z 2021-06-23 2021-06-23T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.22/18298 |
url |
http://hdl.handle.net/10400.22/18298 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Bernardes, B. G., Del Gaudio, P., Alves, P., Costa, R., García-Gonzaléz, C. A., & Oliveira, A. L. (2021). Bioaerogels: Promising Nanostructured Materials in Fluid Management, Healing and Regeneration of Wounds. Molecules, 26(13), 3834. https://www.mdpi.com/1420-3049/26/13/3834 1420-3049 10.3390/molecules26133834 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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