Main Determinants of PON1 Activity in Hemodialysis Patients

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Sandra
Data de Publicação: 2012
Outros Autores: do Sameiro Faria, Maria, Mascarenhas-Melo, Filipa, Freitas, Isabel, Mendonca, Maria Isabel, Nascimento, Henrique, Rocha-Pereira, Petronila, Miranda, Vasco, Mendonça, Denisa, Quintanilha, Alexandre, Belo, Luís, Costa, Elísio, Reis, Flávio, Santos-Silva, Alice
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/35487
Resumo: Cardiovascular diseases are the major cause of morbidity and mortality in hemodialysis (HD) patients. These patients present reduced paraoxonase 1 (PON1) activity that depends on genetic and non-genetic factors; however, how these factors influence PON1 activity in HD patients is poorly clarified. Our aim was to evaluate the influence of two polymorphisms and non-genetic factors on PON1 activity in HD patients.
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spelling Main Determinants of PON1 Activity in Hemodialysis PatientsAdiponectinAgedAged, 80 and overAnemiaAryldialkylphosphataseBiomarkersC-Reactive ProteinEnzyme ActivationErythropoietinFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsInflammationInterleukin-6Kidney Failure, ChronicLipidsMaleMiddle AgedPolymorphism, GeneticPrognosisRisk FactorsRenal DialysisMadeira IslandPortugalCardiovascular diseases are the major cause of morbidity and mortality in hemodialysis (HD) patients. These patients present reduced paraoxonase 1 (PON1) activity that depends on genetic and non-genetic factors; however, how these factors influence PON1 activity in HD patients is poorly clarified. Our aim was to evaluate the influence of two polymorphisms and non-genetic factors on PON1 activity in HD patients.KargerRepositório ComumRibeiro, Sandrado Sameiro Faria, MariaMascarenhas-Melo, FilipaFreitas, IsabelMendonca, Maria IsabelNascimento, HenriqueRocha-Pereira, PetronilaMiranda, VascoMendonça, DenisaQuintanilha, AlexandreBelo, LuísCosta, ElísioReis, FlávioSantos-Silva, Alice2021-02-15T15:31:43Z20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/35487engAm J Nephrol 2012;36:317–32310.1159/000342235info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-10T02:17:31Zoai:comum.rcaap.pt:10400.26/35487Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:34:31.480530Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Main Determinants of PON1 Activity in Hemodialysis Patients
title Main Determinants of PON1 Activity in Hemodialysis Patients
spellingShingle Main Determinants of PON1 Activity in Hemodialysis Patients
Ribeiro, Sandra
Adiponectin
Aged
Aged, 80 and over
Anemia
Aryldialkylphosphatase
Biomarkers
C-Reactive Protein
Enzyme Activation
Erythropoietin
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Inflammation
Interleukin-6
Kidney Failure, Chronic
Lipids
Male
Middle Aged
Polymorphism, Genetic
Prognosis
Risk Factors
Renal Dialysis
Madeira Island
Portugal
title_short Main Determinants of PON1 Activity in Hemodialysis Patients
title_full Main Determinants of PON1 Activity in Hemodialysis Patients
title_fullStr Main Determinants of PON1 Activity in Hemodialysis Patients
title_full_unstemmed Main Determinants of PON1 Activity in Hemodialysis Patients
title_sort Main Determinants of PON1 Activity in Hemodialysis Patients
author Ribeiro, Sandra
author_facet Ribeiro, Sandra
do Sameiro Faria, Maria
Mascarenhas-Melo, Filipa
Freitas, Isabel
Mendonca, Maria Isabel
Nascimento, Henrique
Rocha-Pereira, Petronila
Miranda, Vasco
Mendonça, Denisa
Quintanilha, Alexandre
Belo, Luís
Costa, Elísio
Reis, Flávio
Santos-Silva, Alice
author_role author
author2 do Sameiro Faria, Maria
Mascarenhas-Melo, Filipa
Freitas, Isabel
Mendonca, Maria Isabel
Nascimento, Henrique
Rocha-Pereira, Petronila
Miranda, Vasco
Mendonça, Denisa
Quintanilha, Alexandre
Belo, Luís
Costa, Elísio
Reis, Flávio
Santos-Silva, Alice
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Ribeiro, Sandra
do Sameiro Faria, Maria
Mascarenhas-Melo, Filipa
Freitas, Isabel
Mendonca, Maria Isabel
Nascimento, Henrique
Rocha-Pereira, Petronila
Miranda, Vasco
Mendonça, Denisa
Quintanilha, Alexandre
Belo, Luís
Costa, Elísio
Reis, Flávio
Santos-Silva, Alice
dc.subject.por.fl_str_mv Adiponectin
Aged
Aged, 80 and over
Anemia
Aryldialkylphosphatase
Biomarkers
C-Reactive Protein
Enzyme Activation
Erythropoietin
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Inflammation
Interleukin-6
Kidney Failure, Chronic
Lipids
Male
Middle Aged
Polymorphism, Genetic
Prognosis
Risk Factors
Renal Dialysis
Madeira Island
Portugal
topic Adiponectin
Aged
Aged, 80 and over
Anemia
Aryldialkylphosphatase
Biomarkers
C-Reactive Protein
Enzyme Activation
Erythropoietin
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Inflammation
Interleukin-6
Kidney Failure, Chronic
Lipids
Male
Middle Aged
Polymorphism, Genetic
Prognosis
Risk Factors
Renal Dialysis
Madeira Island
Portugal
description Cardiovascular diseases are the major cause of morbidity and mortality in hemodialysis (HD) patients. These patients present reduced paraoxonase 1 (PON1) activity that depends on genetic and non-genetic factors; however, how these factors influence PON1 activity in HD patients is poorly clarified. Our aim was to evaluate the influence of two polymorphisms and non-genetic factors on PON1 activity in HD patients.
publishDate 2012
dc.date.none.fl_str_mv 2012
2012-01-01T00:00:00Z
2021-02-15T15:31:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/35487
url http://hdl.handle.net/10400.26/35487
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Am J Nephrol 2012;36:317–323
10.1159/000342235
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Karger
publisher.none.fl_str_mv Karger
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799134907127037952

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