Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKD
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.24/1765 |
Resumo: | There is a growing consensus that patients with chronic kidney disease (CKD) should engage in regular exercise, but there is a lack of formal guidelines. In this report, we determined whether combined aerobic and resistance exercise would elicit superior physiological gains, in particular muscular strength, compared with aerobic training alone in nondialysis CKD. Nondialysis patients with CKD stages 3b-5 were randomly allocated to aerobic exercise {AE, n = 21; 9 men; median age 63 [interquartile range (IQR) 58-71] yr; median estimated glomerular filtration rate (eGFR) 24 (IQR 20-30) ml·min-1·1.73 m-2} or combined exercise [CE, n = 20, 9 men, median age 63 (IQR 51-69) yr, median eGFR 27 (IQR 22-32) ml·min-1·1.73 m-2], preceded by a 6-wk run-in control period. Patients then underwent 12 wk of supervised AE (treadmill, rowing, or cycling exercise) or CE training (as AE plus leg extension and leg press exercise) performed three times per week. Outcome assessments of knee extensor muscle strength, quadriceps muscle volume, exercise capacity, and central hemodynamics were performed at baseline, following the 6-wk control period, and at the end of the intervention. AE and CE resulted in significant increases in knee extensor strength of 16 ± 19% (mean ± SD; P = 0.001) and 48 ± 37% ( P < 0.001), respectively, which were greater after CE ( P = 0.02). AE and CE resulted in 5 ± 7% ( P = 0.04) and 9 ± 7% ( P < 0.001) increases in quadriceps volume, respectively ( P < 0.001), which were greater after CE ( P = 0.01). Both AE and CE increased distance walked in the incremental shuttle walk test [28 ± 44 m ( P = 0.01) and 32 ± 45 m ( P = 0.01), respectively]. In nondialysis CKD, the addition of resistance exercise to aerobic exercise confers greater increases in muscle mass and strength than aerobic exercise alone. |
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Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKDAgedCardiorespiratory FitnessEnglandExercise TestExercise TherapyExercise ToleranceFemaleGlomerular Filtration RateHealth StatusHumansKidneyMagnetic Resonance ImagingMaleMiddle AgedQuadriceps MuscleRenal Insufficiency, ChronicSeverity of Illness IndexTime FactorsTreatment OutcomeMuscle StrengthResistance TrainingThere is a growing consensus that patients with chronic kidney disease (CKD) should engage in regular exercise, but there is a lack of formal guidelines. In this report, we determined whether combined aerobic and resistance exercise would elicit superior physiological gains, in particular muscular strength, compared with aerobic training alone in nondialysis CKD. Nondialysis patients with CKD stages 3b-5 were randomly allocated to aerobic exercise {AE, n = 21; 9 men; median age 63 [interquartile range (IQR) 58-71] yr; median estimated glomerular filtration rate (eGFR) 24 (IQR 20-30) ml·min-1·1.73 m-2} or combined exercise [CE, n = 20, 9 men, median age 63 (IQR 51-69) yr, median eGFR 27 (IQR 22-32) ml·min-1·1.73 m-2], preceded by a 6-wk run-in control period. Patients then underwent 12 wk of supervised AE (treadmill, rowing, or cycling exercise) or CE training (as AE plus leg extension and leg press exercise) performed three times per week. Outcome assessments of knee extensor muscle strength, quadriceps muscle volume, exercise capacity, and central hemodynamics were performed at baseline, following the 6-wk control period, and at the end of the intervention. AE and CE resulted in significant increases in knee extensor strength of 16 ± 19% (mean ± SD; P = 0.001) and 48 ± 37% ( P < 0.001), respectively, which were greater after CE ( P = 0.02). AE and CE resulted in 5 ± 7% ( P = 0.04) and 9 ± 7% ( P < 0.001) increases in quadriceps volume, respectively ( P < 0.001), which were greater after CE ( P = 0.01). Both AE and CE increased distance walked in the incremental shuttle walk test [28 ± 44 m ( P = 0.01) and 32 ± 45 m ( P = 0.01), respectively]. In nondialysis CKD, the addition of resistance exercise to aerobic exercise confers greater increases in muscle mass and strength than aerobic exercise alone.Repositório Científico da UMAIAWatson, Emma L.Gould, Douglas W.Wilkinson, Thomas J.Xenophontos, SoterisClarke, Amy L.Vogt, Barbara PerezViana, João L.Smith, Alice C.2021-04-28T14:31:46Z2018-01-01T00:00:00Z2018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://hdl.handle.net/10400.24/1765eng10.1152/ajprenal.00012.2018info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-26T16:01:07Zoai:repositorio.umaia.pt:10400.24/1765Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:10:07.481615Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKD |
title |
Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKD |
spellingShingle |
Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKD Watson, Emma L. Aged Cardiorespiratory Fitness England Exercise Test Exercise Therapy Exercise Tolerance Female Glomerular Filtration Rate Health Status Humans Kidney Magnetic Resonance Imaging Male Middle Aged Quadriceps Muscle Renal Insufficiency, Chronic Severity of Illness Index Time Factors Treatment Outcome Muscle Strength Resistance Training |
title_short |
Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKD |
title_full |
Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKD |
title_fullStr |
Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKD |
title_full_unstemmed |
Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKD |
title_sort |
Twelve-week combined resistance and aerobic training confers greater benefits than aerobic training alone in nondialysis CKD |
author |
Watson, Emma L. |
author_facet |
Watson, Emma L. Gould, Douglas W. Wilkinson, Thomas J. Xenophontos, Soteris Clarke, Amy L. Vogt, Barbara Perez Viana, João L. Smith, Alice C. |
author_role |
author |
author2 |
Gould, Douglas W. Wilkinson, Thomas J. Xenophontos, Soteris Clarke, Amy L. Vogt, Barbara Perez Viana, João L. Smith, Alice C. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico da UMAIA |
dc.contributor.author.fl_str_mv |
Watson, Emma L. Gould, Douglas W. Wilkinson, Thomas J. Xenophontos, Soteris Clarke, Amy L. Vogt, Barbara Perez Viana, João L. Smith, Alice C. |
dc.subject.por.fl_str_mv |
Aged Cardiorespiratory Fitness England Exercise Test Exercise Therapy Exercise Tolerance Female Glomerular Filtration Rate Health Status Humans Kidney Magnetic Resonance Imaging Male Middle Aged Quadriceps Muscle Renal Insufficiency, Chronic Severity of Illness Index Time Factors Treatment Outcome Muscle Strength Resistance Training |
topic |
Aged Cardiorespiratory Fitness England Exercise Test Exercise Therapy Exercise Tolerance Female Glomerular Filtration Rate Health Status Humans Kidney Magnetic Resonance Imaging Male Middle Aged Quadriceps Muscle Renal Insufficiency, Chronic Severity of Illness Index Time Factors Treatment Outcome Muscle Strength Resistance Training |
description |
There is a growing consensus that patients with chronic kidney disease (CKD) should engage in regular exercise, but there is a lack of formal guidelines. In this report, we determined whether combined aerobic and resistance exercise would elicit superior physiological gains, in particular muscular strength, compared with aerobic training alone in nondialysis CKD. Nondialysis patients with CKD stages 3b-5 were randomly allocated to aerobic exercise {AE, n = 21; 9 men; median age 63 [interquartile range (IQR) 58-71] yr; median estimated glomerular filtration rate (eGFR) 24 (IQR 20-30) ml·min-1·1.73 m-2} or combined exercise [CE, n = 20, 9 men, median age 63 (IQR 51-69) yr, median eGFR 27 (IQR 22-32) ml·min-1·1.73 m-2], preceded by a 6-wk run-in control period. Patients then underwent 12 wk of supervised AE (treadmill, rowing, or cycling exercise) or CE training (as AE plus leg extension and leg press exercise) performed three times per week. Outcome assessments of knee extensor muscle strength, quadriceps muscle volume, exercise capacity, and central hemodynamics were performed at baseline, following the 6-wk control period, and at the end of the intervention. AE and CE resulted in significant increases in knee extensor strength of 16 ± 19% (mean ± SD; P = 0.001) and 48 ± 37% ( P < 0.001), respectively, which were greater after CE ( P = 0.02). AE and CE resulted in 5 ± 7% ( P = 0.04) and 9 ± 7% ( P < 0.001) increases in quadriceps volume, respectively ( P < 0.001), which were greater after CE ( P = 0.01). Both AE and CE increased distance walked in the incremental shuttle walk test [28 ± 44 m ( P = 0.01) and 32 ± 45 m ( P = 0.01), respectively]. In nondialysis CKD, the addition of resistance exercise to aerobic exercise confers greater increases in muscle mass and strength than aerobic exercise alone. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01T00:00:00Z 2018-01-01T00:00:00Z 2021-04-28T14:31:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.24/1765 |
url |
http://hdl.handle.net/10400.24/1765 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1152/ajprenal.00012.2018 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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