Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
DOI: | 10.24915/aup.35.1-2.47 |
Texto Completo: | https://doi.org/10.24915/aup.35.1-2.47 |
Resumo: | Introduction: Urinary tract infection (UTI) is one of the most frequent infections at community level, presenting higher costs for society and health system. The publication of epidemiological evaluation studies of etiological agents responsible for UTI and its antimicrobial resistance profile is an added value for the elaboration of decision criteria for antibiotic- empirical therapy, serving as well to alert the health professionals for the benefits of a correct antimicrobial prescription. Material and Methods: Cross-sectional epidemiological study, based on the urine cultures performed to external users of the Clinical Pathology Service of Horta Hospital EPER in the year 2016. On the urine cultures considered positive, parameters such as age, sex, type of bacteria and antimicrobial susceptibility profile were study. All records with insufficient data for analysis, as well as all requests for duplicate urine cultures from the same patient within a period of less than 7 days, were excluded from the study. All the data used were provided by the Clinical Pathology Service of the Horta Hospital EPER. Results: Higher prevalence of positive urine cultures in women compared to men. In women, a bi-modal trend with the first peak occurring in the age group of 30 to 39 years, the second (highest) peak in the 70-79 age group. In men, the tendency to increase occurs beginning from the age group of 50 to 59; the frequency of bacteria isolated between sexes were different. The prevalence of Escherichia coli (major responsible for UTI) in women is higher than in men. The second and third most frequent bacteria were Klebsiella p. Pneumoniae and Proteus mirabilis respectively, with higher frequency in man than in woman in both cases; Major frequency of ESBL occurred in man; the study of antimicrobial profile in Escherichia coli strains showed high sensitivity to fosfomycin (>95%) and nitrofurantoin (>95%). Trimethoprim/ sulfamethoxazole and fluoroquinolones showed high resistance (close to 20%). Amoxicillin and amoxicillin/clavulanic acid with much higher resistance when compared to fosfomycin and nitrofurantoin. Excluding cephalothin, there were some heterogeneity in the cephalosporin group, but with sensitivities always higher than 80%. Conclusion: This type of studies helps to determine the guidelines for an empirical antibiotic therapy. |
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Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016Infeções do Trato Urinário da Comunidade da Ilha do Faial, Determinadas no Hospital da Horta EPER - 2016Urinary Tract Infections/microbiologyUrinary Tract Infections/drug theraphyDrug Resistance, BacterialAzoresAnti-Bacterial AgentsAçoresAntibacterianosFarmacorresistência BacterianaInfeções Urinárias/microbiologiaInfeções Urinárias/ tratamentoIntroduction: Urinary tract infection (UTI) is one of the most frequent infections at community level, presenting higher costs for society and health system. The publication of epidemiological evaluation studies of etiological agents responsible for UTI and its antimicrobial resistance profile is an added value for the elaboration of decision criteria for antibiotic- empirical therapy, serving as well to alert the health professionals for the benefits of a correct antimicrobial prescription. Material and Methods: Cross-sectional epidemiological study, based on the urine cultures performed to external users of the Clinical Pathology Service of Horta Hospital EPER in the year 2016. On the urine cultures considered positive, parameters such as age, sex, type of bacteria and antimicrobial susceptibility profile were study. All records with insufficient data for analysis, as well as all requests for duplicate urine cultures from the same patient within a period of less than 7 days, were excluded from the study. All the data used were provided by the Clinical Pathology Service of the Horta Hospital EPER. Results: Higher prevalence of positive urine cultures in women compared to men. In women, a bi-modal trend with the first peak occurring in the age group of 30 to 39 years, the second (highest) peak in the 70-79 age group. In men, the tendency to increase occurs beginning from the age group of 50 to 59; the frequency of bacteria isolated between sexes were different. The prevalence of Escherichia coli (major responsible for UTI) in women is higher than in men. The second and third most frequent bacteria were Klebsiella p. Pneumoniae and Proteus mirabilis respectively, with higher frequency in man than in woman in both cases; Major frequency of ESBL occurred in man; the study of antimicrobial profile in Escherichia coli strains showed high sensitivity to fosfomycin (>95%) and nitrofurantoin (>95%). Trimethoprim/ sulfamethoxazole and fluoroquinolones showed high resistance (close to 20%). Amoxicillin and amoxicillin/clavulanic acid with much higher resistance when compared to fosfomycin and nitrofurantoin. Excluding cephalothin, there were some heterogeneity in the cephalosporin group, but with sensitivities always higher than 80%. Conclusion: This type of studies helps to determine the guidelines for an empirical antibiotic therapy.Introdução: A infeção do trato urinário (ITU) é uma das infeções mais frequentes a nível comunitário, apresentando custos mais elevados para a sociedade e para o sistema de saúde. A publicação de estudos de avaliação epidemiológica dos agentes etiológicos responsáveis pela ITU e o seu perfil de resistências antimicrobianas constitui uma mais-valia para a elaboração de critérios de decisão para antibiótico-terapia empírica, bem como para alertar os responsáveis na área da saúde no que respeita aos benefícios de uma prescrição correta dos antimicrobianos. Material e Métodos: Estudo epidemiológico do tipo transversal, baseado nas uroculturas realizadas aos utentes externos do serviço de Patologia Clínica do Hospital da Horta EPER no ano de 2016. Sobre as uroculturas consideradas positivas foram analisados parâmetros como a idade, sexo, tipo de bactéria e perfil de suscetibilidade a antimicrobianos. Foram excluídos do estudo todos os registos com dados insuficientes para análise, bem como todos os pedidos de uroculturas em duplicado e do mesmo paciente num prazo inferior a 7 dias. Todos os dados utilizados foram disponibilizados pelo Serviço de Patologia Clínica do Hospital da Horta EPER. Resultados: Maior prevalência de uroculturas positivas nas mulheres comparativamente com os homens. Nas mulheres tendência bi-modal com primeiro pico a ocorrer na faixa etária dos 30 aos 39 anos, o segundo pico (mais elevado) na faixa dos 70 aos 79 anos. Nos homens, a tendência de aumento ocorre a partir da faixa etária dos 50 aos 59; a frequência das bactérias isoladas entre sexos é diferente. Predomínio da Escherichia coli como principal causadora de ITU, na mulher é mais alta do que no homem. A segunda e terceira bactéria mais frequentes foram a Klebsiella p. pneumoniae e Proteus mirabilis respetivamente, com maior frequência no homem do que na mulher em ambos os casos; maior frequência de beta lactamases de espectro estendido ocorre no homem; o estudo do perfil antimicrobiano nas estirpes de Escherichia coli apresentou elevada sensibilidade à fosfomicina (> 95%) e nitrofurantoína (> 95%). O timetroprim/sulfametoxazol e as fluoroquinolonas apresentaram resistências elevadas, (próxima dos 20%). A amoxicilina e amoxicilina/ácido clavulânico com resistências muito mais elevadas quando comparadas com a fosfomicina e nitrofurantoína. Excluindo a cefalotina, no grupo das cefalosporinas existe alguma heterogeneidade, mas com sensibilidades sempre superiores a 80%. Conclusão: Este tipo de estudos permite ajudar a determinar as linhas orientadoras para uma elaboração de antibiótico-terapia empírica.Associação Portuguesa de Urologia2018-07-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.24915/aup.35.1-2.47oai:oai.actaurologicaportuguesa.com:article/47Acta Urológica Portuguesa; Vol. 35 No. 1-2 (2018): January-March; April-June; 20-27Acta Urológica Portuguesa; v. 35 n. 1-2 (2018): janeiro-março; abril-junho; 20-272387-04192341-4022reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttp://www.actaurologicaportuguesa.com/index.php/aup/article/view/47https://doi.org/10.24915/aup.35.1-2.47http://www.actaurologicaportuguesa.com/index.php/aup/article/view/47/32Copyright (c) 2018 Portuguese Association of Urologyinfo:eu-repo/semantics/openAccessBorges de Sousa, Rui Pedro2022-09-21T09:04:46Zoai:oai.actaurologicaportuguesa.com:article/47Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:55:53.078291Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 Infeções do Trato Urinário da Comunidade da Ilha do Faial, Determinadas no Hospital da Horta EPER - 2016 |
title |
Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 |
spellingShingle |
Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 Borges de Sousa, Rui Pedro Urinary Tract Infections/microbiology Urinary Tract Infections/drug theraphy Drug Resistance, Bacterial Azores Anti-Bacterial Agents Açores Antibacterianos Farmacorresistência Bacteriana Infeções Urinárias/microbiologia Infeções Urinárias/ tratamento Borges de Sousa, Rui Pedro Urinary Tract Infections/microbiology Urinary Tract Infections/drug theraphy Drug Resistance, Bacterial Azores Anti-Bacterial Agents Açores Antibacterianos Farmacorresistência Bacteriana Infeções Urinárias/microbiologia Infeções Urinárias/ tratamento |
title_short |
Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 |
title_full |
Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 |
title_fullStr |
Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 |
title_full_unstemmed |
Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 |
title_sort |
Urinary Tract Infections of Faial Island Community, Determined in Hospital da Horta EPER - 2016 |
author |
Borges de Sousa, Rui Pedro |
author_facet |
Borges de Sousa, Rui Pedro Borges de Sousa, Rui Pedro |
author_role |
author |
dc.contributor.author.fl_str_mv |
Borges de Sousa, Rui Pedro |
dc.subject.por.fl_str_mv |
Urinary Tract Infections/microbiology Urinary Tract Infections/drug theraphy Drug Resistance, Bacterial Azores Anti-Bacterial Agents Açores Antibacterianos Farmacorresistência Bacteriana Infeções Urinárias/microbiologia Infeções Urinárias/ tratamento |
topic |
Urinary Tract Infections/microbiology Urinary Tract Infections/drug theraphy Drug Resistance, Bacterial Azores Anti-Bacterial Agents Açores Antibacterianos Farmacorresistência Bacteriana Infeções Urinárias/microbiologia Infeções Urinárias/ tratamento |
description |
Introduction: Urinary tract infection (UTI) is one of the most frequent infections at community level, presenting higher costs for society and health system. The publication of epidemiological evaluation studies of etiological agents responsible for UTI and its antimicrobial resistance profile is an added value for the elaboration of decision criteria for antibiotic- empirical therapy, serving as well to alert the health professionals for the benefits of a correct antimicrobial prescription. Material and Methods: Cross-sectional epidemiological study, based on the urine cultures performed to external users of the Clinical Pathology Service of Horta Hospital EPER in the year 2016. On the urine cultures considered positive, parameters such as age, sex, type of bacteria and antimicrobial susceptibility profile were study. All records with insufficient data for analysis, as well as all requests for duplicate urine cultures from the same patient within a period of less than 7 days, were excluded from the study. All the data used were provided by the Clinical Pathology Service of the Horta Hospital EPER. Results: Higher prevalence of positive urine cultures in women compared to men. In women, a bi-modal trend with the first peak occurring in the age group of 30 to 39 years, the second (highest) peak in the 70-79 age group. In men, the tendency to increase occurs beginning from the age group of 50 to 59; the frequency of bacteria isolated between sexes were different. The prevalence of Escherichia coli (major responsible for UTI) in women is higher than in men. The second and third most frequent bacteria were Klebsiella p. Pneumoniae and Proteus mirabilis respectively, with higher frequency in man than in woman in both cases; Major frequency of ESBL occurred in man; the study of antimicrobial profile in Escherichia coli strains showed high sensitivity to fosfomycin (>95%) and nitrofurantoin (>95%). Trimethoprim/ sulfamethoxazole and fluoroquinolones showed high resistance (close to 20%). Amoxicillin and amoxicillin/clavulanic acid with much higher resistance when compared to fosfomycin and nitrofurantoin. Excluding cephalothin, there were some heterogeneity in the cephalosporin group, but with sensitivities always higher than 80%. Conclusion: This type of studies helps to determine the guidelines for an empirical antibiotic therapy. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-07-24T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
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https://doi.org/10.24915/aup.35.1-2.47 oai:oai.actaurologicaportuguesa.com:article/47 |
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https://doi.org/10.24915/aup.35.1-2.47 |
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oai:oai.actaurologicaportuguesa.com:article/47 |
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por |
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http://www.actaurologicaportuguesa.com/index.php/aup/article/view/47 https://doi.org/10.24915/aup.35.1-2.47 http://www.actaurologicaportuguesa.com/index.php/aup/article/view/47/32 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Portuguese Association of Urology info:eu-repo/semantics/openAccess |
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Copyright (c) 2018 Portuguese Association of Urology |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Associação Portuguesa de Urologia |
publisher.none.fl_str_mv |
Associação Portuguesa de Urologia |
dc.source.none.fl_str_mv |
Acta Urológica Portuguesa; Vol. 35 No. 1-2 (2018): January-March; April-June; 20-27 Acta Urológica Portuguesa; v. 35 n. 1-2 (2018): janeiro-março; abril-junho; 20-27 2387-0419 2341-4022 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1822183306328801280 |
dc.identifier.doi.none.fl_str_mv |
10.24915/aup.35.1-2.47 |